PubMed

Insulin resistance, impaired early insulin response, and insulin propeptides as predictors of the development of type 2 diabetes: a population-based, 7-year follow-up study in 70-year-old men.

Zethelius B, Hales CN, Lithell HO, Berne C.

Diabetes Care. 2004 Jun;27(6):1433-8.PMID: 15161800 [PubMed - indexed for MEDLINE]Related articlesFree article

Proinsulin and acute insulin response independently predict Type 2 diabetes mellitus in men--report from 27 years of follow-up study.

Zethelius B, Byberg L, Hales CN, Lithell H, Berne C.

Diabetologia. 2003 Jan;46(1):20-6. Epub 2003 Jan 8.PMID: 12637978 [PubMed - indexed for MEDLINE]Related articles

Insulin sensitivity, proinsulin and insulin as predictors of coronary heart disease. A population-based 10-year, follow-up study in 70-year old men using the euglycaemic insulin clamp.

Zethelius B, Lithell H, Hales CN, Berne C.

Diabetologia. 2005 May;48(5):862-7. Epub 2005 Apr 1.PMID: 15803331 [PubMed - indexed for MEDLINE]Related articles

Fasting proinsulin concentrations predict the development of type 2 diabetes.

Wareham NJ, Byrne CD, Williams R, Day NE, Hales CN.

Diabetes Care. 1999 Feb;22(2):262-70.PMID: 10333943 [PubMed - indexed for MEDLINE]Related articlesFree article

Intact proinsulin, des 31,32 proinsulin, and specific insulin concentrations among nondiabetic and diabetic subjects in populations at varying risk of type 2 diabetes.

Nagi DK, Knowler WC, Mohamed-Ali V, Bennett PH, Yudkin JS.

Diabetes Care. 1998 Jan;21(1):127-33.PMID: 9538983 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased proinsulin levels and decreased acute insulin response independently predict the incidence of type 2 diabetes in the insulin resistance atherosclerosis study.

Hanley AJ, D'Agostino R Jr, Wagenknecht LE, Saad MF, Savage PJ, Bergman R, Haffner SM; Insluin Resistance Atrherosclerosis Study.

Diabetes. 2002 Apr;51(4):1263-70.PMID: 11916954 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin sensitivity measured by the euglycaemic insulin clamp and proinsulin levels as predictors of stroke in elderly men.

Wiberg B, Sundström J, Zethelius B, Lind L.

Diabetologia. 2009 Jan;52(1):90-6. Epub 2008 Oct 24.PMID: 18949454 [PubMed - indexed for MEDLINE]Related articles

Are specific serum insulin levels low in impaired glucose tolerance and type II diabetes?: measurement with a radioimmunoassay blind to proinsulin, in the population of Wadena, Minnesota.

Goetz FC, French LR, Thomas W, Gingerich RL, Clements JP.

Metabolism. 1995 Oct;44(10):1371-6.PMID: 7476300 [PubMed - indexed for MEDLINE]Related articles

Proinsulin is an independent predictor of coronary heart disease: Report from a 27-year follow-up study.

Zethelius B, Byberg L, Hales CN, Lithell H, Berne C.

Circulation. 2002 May 7;105(18):2153-8.PMID: 11994248 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin, proinsulin, proinsulin:insulin ratio, and the risk of developing type 2 diabetes mellitus in women.

Pradhan AD, Manson JE, Meigs JB, Rifai N, Buring JE, Liu S, Ridker PM.

Am J Med. 2003 Apr 15;114(6):438-44.PMID: 12727576 [PubMed - indexed for MEDLINE]Related articles

Fasting proinsulin and 2-h post-load glucose levels predict the conversion to NIDDM in subjects with impaired glucose tolerance: the Hoorn Study.

Nijpels G, Popp-Snijders C, Kostense PJ, Bouter LM, Heine RJ.

Diabetologia. 1996 Jan;39(1):113-8.PMID: 8720611 [PubMed - indexed for MEDLINE]Related articles

High incidence of glucose intolerance in Asian-Indian subjects with acute coronary syndrome.

Ramachandran A, Chamukuttan S, Immaneni S, Shanmugam RM, Vishnu N, Viswanathan V, Jaakko T.

Diabetes Care. 2005 Oct;28(10):2492-6.PMID: 16186285 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor-binding protein-1 in the prediction and development of type 2 diabetes in middle-aged Swedish men.

Lewitt MS, Hilding A, Ostenson CG, Efendic S, Brismar K, Hall K.

Diabetologia. 2008 Jul;51(7):1135-45. Epub 2008 May 22.PMID: 18496669 [PubMed - indexed for MEDLINE]Related articles

Contribution of abnormal insulin secretion and insulin resistance to the pathogenesis of type 2 diabetes in myotonic dystrophy.

Perseghin G, Caumo A, Arcelloni C, Benedini S, Lanzi R, Pagliato E, Sereni LP, Testolin G, Battezzati A, Comi G, Comola M, Luzi L.

Diabetes Care. 2003 Jul;26(7):2112-8.PMID: 12832322 [PubMed - indexed for MEDLINE]Related articlesFree article

Population-based incidence rates and risk factors for type 2 diabetes in white individuals: the Bruneck study.

Bonora E, Kiechl S, Willeit J, Oberhollenzer F, Egger G, Meigs JB, Bonadonna RC, Muggeo M; Bruneck study.

Diabetes. 2004 Jul;53(7):1782-9.PMID: 15220202 [PubMed - indexed for MEDLINE]Related articlesFree article

The impact of insulin resistance on proinsulin secretion in pregnancy: hyperproinsulinemia is not a feature of gestational diabetes.

Retnakaran R, Hanley AJ, Sermer M, Zinman B.

Diabetes Care. 2005 Nov;28(11):2710-5.PMID: 16249544 [PubMed - indexed for MEDLINE]Related articlesFree article

The relation of proinsulin and insulin to insulin sensitivity and acute insulin response in subjects with newly diagnosed type II diabetes: the Insulin Resistance Atherosclerosis Study.

Mykkänen L, Zaccaro DJ, Hales CN, Festa A, Haffner SM.

Diabetologia. 1999 Sep;42(9):1060-6.PMID: 10447516 [PubMed - indexed for MEDLINE]Related articles

Impaired insulin sensitivity, insulin secretion, and glucose effectiveness predict future development of impaired glucose tolerance and type 2 diabetes in pre-diabetic African Americans: implications for primary diabetes prevention.

Osei K, Rhinesmith S, Gaillard T, Schuster D.

Diabetes Care. 2004 Jun;27(6):1439-46.PMID: 15161801 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell dysfunction in subjects with impaired glucose tolerance and early type 2 diabetes: comparison of surrogate markers with first-phase insulin secretion from an intravenous glucose tolerance test.

Festa A, Williams K, Hanley AJ, Haffner SM.

Diabetes. 2008 Jun;57(6):1638-44. Epub 2008 Mar 10.PMID: 18332099 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperproinsulinemia is not a characteristic feature in the offspring of patients with different phenotypes of type II diabetes.

Vauhkonen IK, Niskanen LK, Mykkänen L, Haffner SM, Uusitupa MI, Laakso M.

Eur J Endocrinol. 2000 Aug;143(2):251-60.PMID: 10913945 [PubMed - indexed for MEDLINE]Related articlesFree article