PubMed

The Arg972 variant in insulin receptor substrate-1 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.

Sesti G, Marini MA, Cardellini M, Sciacqua A, Frontoni S, Andreozzi F, Irace C, Lauro D, Gnasso A, Federici M, Perticone F, Lauro R.

Diabetes Care. 2004 Jun;27(6):1394-8.PMID: 15161794 [PubMed - indexed for MEDLINE]Related articlesFree article

The E23K variant of KCNJ11 encoding the pancreatic beta-cell adenosine 5'-triphosphate-sensitive potassium channel subunit Kir6.2 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.

Sesti G, Laratta E, Cardellini M, Andreozzi F, Del Guerra S, Irace C, Gnasso A, Grupillo M, Lauro R, Hribal ML, Perticone F, Marchetti P.

J Clin Endocrinol Metab. 2006 Jun;91(6):2334-9. Epub 2006 Apr 4.PMID: 16595597 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction between the G1057D variant of IRS-2 and overweight in the pathogenesis of type 2 diabetes.

Mammarella S, Romano F, Di Valerio A, Creati B, Esposito DL, Palmirotta R, Capani F, Vitullo P, Volpe G, Battista P, Della Loggia F, Mariani-Costantini R, Cama A.

Hum Mol Genet. 2000 Oct 12;9(17):2517-21.PMID: 11030756 [PubMed - indexed for MEDLINE]Related articlesFree article

Amino acid polymorphism Gly 972 Arg in IRS-1 is not associated to lower clamp-derived insulin sensitivity in young healthy first degree relatives of patients with type 2 diabetes.

Koch M, Rett K, Volk A, Maerker E, Haist K, Deninger M, Renn W, Häring HU.

Exp Clin Endocrinol Diabetes. 1999;107(5):318-22.PMID: 10482045 [PubMed - indexed for MEDLINE]Related articles

Glutamic acid decarboxylase antibodies in non-insulin-dependent diabetes patients with secondary sulfonylurea failure in Thailand.

Rattarasarn C, Aguilar Diosdado M, Soonthornpun S.

Diabetes Res Clin Pract. 1997 Sep;37(3):193-7.PMID: 9306041 [PubMed - indexed for MEDLINE]Related articles

Secondary failure rates associated with metformin and sulfonylurea therapy for type 2 diabetes mellitus.

Eurich DT, Simpson SH, Majumdar SR, Johnson JA.

Pharmacotherapy. 2005 Jun;25(6):810-6.PMID: 15927899 [PubMed - indexed for MEDLINE]Related articles

Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: a multinational, randomized, open-label, two-period, crossover noninferiority trial.

Barnett AH, Burger J, Johns D, Brodows R, Kendall DM, Roberts A, Trautmann ME.

Clin Ther. 2007 Nov;29(11):2333-48.PMID: 18158075 [PubMed - indexed for MEDLINE]Related articles

[Association of Pro12Ala variant in peroxisome proliferator-activated receptor-gamma2 gene with type 2 diabetes mellitus]

Fu M, Chen H, Li X, Li J, Wu B, Cheng L, Cai M, Fu Z.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2002 Jun;19(3):234-8. Chinese. PMID: 12048686 [PubMed - indexed for MEDLINE]Related articles

Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Mexican Americans with Type 2 diabetes mellitus.

Celi FS, Negri C, Tanner K, Raben N, De Pablo F, Rovira A, Pallardo LF, Martin-Vaquero P, Stern MP, Mitchell BD, Shuldiner AR.

Diabetes Metab Res Rev. 2000 Sep-Oct;16(5):370-7.PMID: 11025561 [PubMed - indexed for MEDLINE]Related articles

The Gly972-->Arg IRS-1 variant is associated with type 1 diabetes in continental Italy.

Federici M, Petrone A, Porzio O, Bizzarri C, Lauro D, D'Alfonso R, Patera I, Cappa M, Nisticò L, Baroni M, Sesti G, di Mario U, Lauro R, Buzzetti R.

Diabetes. 2003 Mar;52(3):887-90.PMID: 12606535 [PubMed - indexed for MEDLINE]Related articlesFree article

The Arg972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients.

Marini MA, Frontoni S, Mineo D, Bracaglia D, Cardellini M, De Nicolais P, Baroni A, D'Alfonso R, Perna M, Lauro D, Federici M, Gambardella S, Lauro R, Sesti G.

J Clin Endocrinol Metab. 2003 Jul;88(7):3368-71.PMID: 12843189 [PubMed - indexed for MEDLINE]Related articlesFree article

[Identification of factors predicting early evolution of secondary oral hypoglycaemic agent failure and evaluation of clinical standards applied by primary care physicians during qualification to insulin therapy of patients with type 2 diabetes]

Machoy M.

Ann Acad Med Stetin. 2004;50(2):29-39. Polish. PMID: 16529163 [PubMed - indexed for MEDLINE]Related articles

The Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells.

Porzio O, Federici M, Hribal ML, Lauro D, Accili D, Lauro R, Borboni P, Sesti G.

J Clin Invest. 1999 Aug;104(3):357-64.PMID: 10430617 [PubMed - indexed for MEDLINE]Related articlesFree article

The insulin receptor substrate-1 Gly972Arg polymorphism is not associated with Type 2 diabetes mellitus in two population-based studies.

van Dam RM, Hoebee B, Seidell JC, Schaap MM, Blaak EE, Feskens EJ.

Diabet Med. 2004 Jul;21(7):752-8.PMID: 15209769 [PubMed - indexed for MEDLINE]Related articles

Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes.

Florez JC, Sjögren M, Burtt N, Orho-Melander M, Schayer S, Sun M, Almgren P, Lindblad U, Tuomi T, Gaudet D, Hudson TJ, Daly MJ, Ardlie KG, Hirschhorn JN, Altshuler D, Groop L.

Diabetes. 2004 Dec;53(12):3313-8.PMID: 15561965 [PubMed - indexed for MEDLINE]Related articlesFree article

Sulfonylurea receptor gene 16-3 polymorphism - association with sulfonylurea or insulin treatment in type 2 diabetic subjects.

Zychma MJ, Gumprecht J, Strojek K, Grzeszczak W, Moczulski D, Trautsolt W, Karasek D.

Med Sci Monit. 2002 Jul;8(7):CR512-5.PMID: 12118200 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect on metabolic control of second-generation sulfonylurea drugs in patients with NIDDM after secondary failure to first-generation agents.

Sami T, Kabadi UM, Moshiri S.

J Fam Pract. 1996 Oct;43(4):370-4.PMID: 8874372 [PubMed - indexed for MEDLINE]Related articles

Interaction effect between common polymorphisms in PPARgamma2 (Pro12Ala) and insulin receptor substrate 1 (Gly972Arg) on insulin sensitivity.

Stumvoll M, Stefan N, Fritsche A, Madaus A, Tschritter O, Koch M, Machicao F, Häring H.

J Mol Med. 2002 Jan;80(1):33-8. Epub 2001 Sep 15.PMID: 11862322 [PubMed - indexed for MEDLINE]Related articles

Triple therapy in type 2 diabetes: insulin glargine or rosiglitazone added to combination therapy of sulfonylurea plus metformin in insulin-naive patients.

Rosenstock J, Sugimoto D, Strange P, Stewart JA, Soltes-Rak E, Dailey G.

Diabetes Care. 2006 Mar;29(3):554-9.PMID: 16505505 [PubMed - indexed for MEDLINE]Related articlesFree article

[Effect of the Gly972Arg, SNP43 and Prol2Ala polymorphisms of the genes IRS1, CAPN10 and PPARG2 on secondary failure to sulphonylurea and metformin in patients with type 2 diabetes in Yucatán, México]

García-Escalante MG, Suárez-Solís VM, López-Avila MT, Pinto-Escalante Ddel C, Laviada-Molina H.

Invest Clin. 2009 Mar;50(1):65-76. Spanish. PMID: 19418728 [PubMed - indexed for MEDLINE]Related articles