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    Results: 1 to 20 of 436

    1.

    Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2b and -3.

    Kulkarni RN, Roper MG, Dahlgren G, Shih DQ, Kauri LM, Peters JL, Stoffel M, Kennedy RT.

    Diabetes. 2004 Jun;53(6):1517-25.PMID: 15161756 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Insulin receptor substrate 1 regulation of sarco-endoplasmic reticulum calcium ATPase 3 in insulin-secreting beta-cells.

    Borge PD Jr, Wolf BA.

    J Biol Chem. 2003 Mar 28;278(13):11359-68. Epub 2003 Jan 10.PMID: 12524443 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Dynamic imaging of endoplasmic reticulum Ca2+ concentration in insulin-secreting MIN6 Cells using recombinant targeted cameleons: roles of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2 and ryanodine receptors.

    Varadi A, Rutter GA.

    Diabetes. 2002 Feb;51 Suppl 1:S190-201.PMID: 11815480 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Effect of the insulin mimetic L-783,281 on intracellular Ca2+ and insulin secretion from pancreatic beta-cells.

    Roper MG, Qian WJ, Zhang BB, Kulkarni RN, Kahn CR, Kennedy RT.

    Diabetes. 2002 Feb;51 Suppl 1:S43-9.PMID: 11815457 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Insulin regulation of beta-cell function involves a feedback loop on SERCA gene expression, Ca(2+) homeostasis, and insulin expression and secretion.

    Xu GG, Gao ZY, Borge PD Jr, Jegier PA, Young RA, Wolf BA.

    Biochemistry. 2000 Dec 5;39(48):14912-9.PMID: 11101307 [PubMed - indexed for MEDLINE]Related articles

    6.

    Glucose-induced mixed [Ca2+]c oscillations in mouse beta-cells are controlled by the membrane potential and the SERCA3 Ca2+-ATPase of the endoplasmic reticulum.

    Beauvois MC, Merezak C, Jonas JC, Ravier MA, Henquin JC, Gilon P.

    Am J Physiol Cell Physiol. 2006 Jun;290(6):C1503-11. Epub 2005 Dec 28.PMID: 16381799 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Insulin receptor signaling and sarco/endoplasmic reticulum calcium ATPase in beta-cells.

    Borge PD, Moibi J, Greene SR, Trucco M, Young RA, Gao Z, Wolf BA.

    Diabetes. 2002 Dec;51 Suppl 3:S427-33. Review.PMID: 12475786 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    SERCA3 ablation does not impair insulin secretion but suggests distinct roles of different sarcoendoplasmic reticulum Ca(2+) pumps for Ca(2+) homeostasis in pancreatic beta-cells.

    Arredouani A, Guiot Y, Jonas JC, Liu LH, Nenquin M, Pertusa JA, Rahier J, Rolland JF, Shull GE, Stevens M, Wuytack F, Henquin JC, Gilon P.

    Diabetes. 2002 Nov;51(11):3245-53.PMID: 12401716 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.

    Kulkarni RN, Winnay JN, Daniels M, Brüning JC, Flier SN, Hanahan D, Kahn CR.

    J Clin Invest. 1999 Dec;104(12):R69-75.PMID: 10606633 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Defective glucose-dependent endoplasmic reticulum Ca2+ sequestration in diabetic mouse islets of Langerhans.

    Roe MW, Philipson LH, Frangakis CJ, Kuznetsov A, Mertz RJ, Lancaster ME, Spencer B, Worley JF 3rd, Dukes ID.

    J Biol Chem. 1994 Jul 15;269(28):18279-82.PMID: 8034570 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice.

    Cantley J, Choudhury AI, Asare-Anane H, Selman C, Lingard S, Heffron H, Herrera P, Persaud SJ, Withers DJ.

    Diabetologia. 2007 Jun;50(6):1248-56. Epub 2007 Mar 29.PMID: 17393136 [PubMed - indexed for MEDLINE]Related articles

    12.

    Role for plasma membrane-related Ca2+-ATPase-1 (ATP2C1) in pancreatic beta-cell Ca2+ homeostasis revealed by RNA silencing.

    Mitchell KJ, Tsuboi T, Rutter GA.

    Diabetes. 2004 Feb;53(2):393-400.PMID: 14747290 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Restitution of defective glucose-stimulated insulin release of sulfonylurea type 1 receptor knockout mice by acetylcholine.

    Doliba NM, Qin W, Vatamaniuk MZ, Li C, Zelent D, Najafi H, Buettger CW, Collins HW, Carr RD, Magnuson MA, Matschinsky FM.

    Am J Physiol Endocrinol Metab. 2004 May;286(5):E834-43. Epub 2004 Jan 21.PMID: 14736703 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Isoforms of endoplasmic reticulum Ca(2+)-ATPase are differentially expressed in normal and diabetic islets of Langerhans.

    Váradi A, Molnár E, Ostenson CG, Ashcroft SJ.

    Biochem J. 1996 Oct 15;319 ( Pt 2):521-7.PMID: 8912690 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Receptors for insulin and insulin-like growth factor-1 and insulin receptor substrate-1 mediate pathways that regulate islet function.

    Kulkarni RN.

    Biochem Soc Trans. 2002 Apr;30(2):317-22. Review.PMID: 12023872 [PubMed - indexed for MEDLINE]Related articles

    16.

    Insulin receptor substrate 1-induced inhibition of endoplasmic reticulum Ca2+ uptake in beta-cells. Autocrine regulation of intracellular ca2+ homeostasis and insulin secretion.

    Xu GG, Gao ZY, Borge PD Jr, Wolf BA.

    J Biol Chem. 1999 Jun 18;274(25):18067-74.PMID: 10364259 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Glucose inhibits glucagon secretion by a direct effect on mouse pancreatic alpha cells.

    Vieira E, Salehi A, Gylfe E.

    Diabetologia. 2007 Feb;50(2):370-9. Epub 2006 Nov 29.PMID: 17136393 [PubMed - indexed for MEDLINE]Related articles

    18.

    Evidence of diminished glucose stimulation and endoplasmic reticulum function in nonoscillatory pancreatic islets.

    Jahanshahi P, Wu R, Carter JD, Nunemaker CS.

    Endocrinology. 2009 Feb;150(2):607-15. Epub 2008 Sep 25.PMID: 18818288 [PubMed - indexed for MEDLINE]Related articles

    19.

    Inhibition of insulin secretion via distinct signaling pathways in alpha2-adrenoceptor knockout mice.

    Peterhoff M, Sieg A, Brede M, Chao CM, Hein L, Ullrich S.

    Eur J Endocrinol. 2003 Oct;149(4):343-50.PMID: 14514350 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

    Johnson JD, Kuang S, Misler S, Polonsky KS.

    FASEB J. 2004 May;18(7):878-80. Epub 2004 Mar 19.PMID: 15033925 [PubMed - indexed for MEDLINE]Related articlesFree article

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