PubMed

Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type 1 diabetes by activated CD1d-restricted invariant natural killer T-cells.

Mi QS, Ly D, Zucker P, McGarry M, Delovitch TL.

Diabetes. 2004 May;53(5):1303-10.PMID: 15111500 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes.

Sharif S, Arreaza GA, Zucker P, Mi QS, Sondhi J, Naidenko OV, Kronenberg M, Koezuka Y, Delovitch TL, Gombert JM, Leite-De-Moraes M, Gouarin C, Zhu R, Hameg A, Nakayama T, Taniguchi M, Lepault F, Lehuen A, Bach JF, Herbelin A.

Nat Med. 2001 Sep;7(9):1057-62.PMID: 11533711 [PubMed - indexed for MEDLINE]Related articles

Protection from type 1 diabetes by invariant NK T cells requires the activity of CD4+CD25+ regulatory T cells.

Ly D, Mi QS, Hussain S, Delovitch TL.

J Immunol. 2006 Sep 15;177(6):3695-704.PMID: 16951329 [PubMed - indexed for MEDLINE]Related articlesFree article

CD1d-restricted NKT regulatory cells: functional genomic analyses provide new insights into the mechanisms of protection against Type 1 diabetes.

Mi QS, Meagher C, Delovitch TL.

Novartis Found Symp. 2003;252:146-60; discussion 160-4, 203-10. Review.PMID: 14609217 [PubMed - indexed for MEDLINE]Related articles

Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets.

Naumov YN, Bahjat KS, Gausling R, Abraham R, Exley MA, Koezuka Y, Balk SB, Strominger JL, Clare-Salzer M, Wilson SB.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13838-43. Epub 2001 Nov 13.PMID: 11707602 [PubMed - indexed for MEDLINE]Related articlesFree article

NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen.

Laloux V, Beaudoin L, Jeske D, Carnaud C, Lehuen A.

J Immunol. 2001 Mar 15;166(6):3749-56.PMID: 11238616 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of regulatory invariant CD1d-restricted natural killer T-cells in protection against type 1 diabetes.

Hussain S, Wagner M, Ly D, Delovitch TL.

Immunol Res. 2005;31(3):177-88. Review.PMID: 15888910 [PubMed - indexed for MEDLINE]Related articles

Up-regulation of CD1d expression restores the immunoregulatory function of NKT cells and prevents autoimmune diabetes in nonobese diabetic mice.

Falcone M, Facciotti F, Ghidoli N, Monti P, Olivieri S, Zaccagnino L, Bonifacio E, Casorati G, Sanvito F, Sarvetnick N.

J Immunol. 2004 May 15;172(10):5908-16.PMID: 15128771 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of invariant NK T cells protects against experimental rheumatoid arthritis by an IL-10-dependent pathway.

Miellot A, Zhu R, Diem S, Boissier MC, Herbelin A, Bessis N.

Eur J Immunol. 2005 Dec;35(12):3704-13.PMID: 16304639 [PubMed - indexed for MEDLINE]Related articles

Prevention of type 1 diabetes by invariant NKT cells is independent of peripheral CD1d expression.

Novak J, Beaudoin L, Park S, Griseri T, Teyton L, Bendelac A, Lehuen A.

J Immunol. 2007 Feb 1;178(3):1332-40.PMID: 17237379 [PubMed - indexed for MEDLINE]Related articlesFree article

The complementarity determining region 2 of BV8S2 (V beta 8.2) contributes to antigen recognition by rat invariant NKT cell TCR.

Pyz E, Naidenko O, Miyake S, Yamamura T, Berberich I, Cardell S, Kronenberg M, Herrmann T.

J Immunol. 2006 Jun 15;176(12):7447-55.PMID: 16751390 [PubMed - indexed for MEDLINE]Related articlesFree article

The natural killer T-cell ligand alpha-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice.

Hong S, Wilson MT, Serizawa I, Wu L, Singh N, Naidenko OV, Miura T, Haba T, Scherer DC, Wei J, Kronenberg M, Koezuka Y, Van Kaer L.

Nat Med. 2001 Sep;7(9):1052-6.PMID: 11533710 [PubMed - indexed for MEDLINE]Related articles

Activation of invariant NKT cells confers protection against Chlamydia trachomatis-induced arthritis.

Bharhani MS, Chiu B, Na KS, Inman RD.

Int Immunol. 2009 Jul;21(7):859-70. Epub 2009 May 28.PMID: 19477915 [PubMed - indexed for MEDLINE]Related articles

Regulatory natural killer T cells protect against spontaneous and recurrent type 1 diabetes.

Sharif S, Arreaza GA, Zucker P, Delovitch TL.

Ann N Y Acad Sci. 2002 Apr;958:77-88. Review.PMID: 12021086 [PubMed - indexed for MEDLINE]Related articles

Combination therapy with cyclosporine and interleukin-4 or interleukin-10 prolongs survival of synergeneic pancreatic islet grafts in nonobese diabetic mice: islet graft survival does not correlate with mRNA levels of type 1 or type 2 cytokines, or transforming growth factor-beta in the islet grafts.

Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Rajotte RV, Power RF.

Transplantation. 1997 Dec 15;64(11):1525-31.PMID: 9415551 [PubMed - indexed for MEDLINE]Related articles

Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice.

Saubermann LJ, Beck P, De Jong YP, Pitman RS, Ryan MS, Kim HS, Exley M, Snapper S, Balk SP, Hagen SJ, Kanauchi O, Motoki K, Sakai T, Terhorst C, Koezuka Y, Podolsky DK, Blumberg RS.

Gastroenterology. 2000 Jul;119(1):119-28.PMID: 10889161 [PubMed - indexed for MEDLINE]Related articles

Combined therapy with interleukin-4 and interleukin-10 inhibits autoimmune diabetes recurrence in syngeneic islet-transplanted nonobese diabetic mice. Analysis of cytokine mRNA expression in the graft.

Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Bleackley RC, Power RF, Rajotte RV.

Transplantation. 1995 Aug 27;60(4):368-74.PMID: 7652767 [PubMed - indexed for MEDLINE]Related articles

CD1d-restricted NKT cell activation enhanced homeostatic proliferation of CD8+ T cells in a manner dependent on IL-4.

Ueda N, Kuki H, Kamimura D, Sawa S, Seino K, Tashiro T, Fushuku K, Taniguchi M, Hirano T, Murakami M.

Int Immunol. 2006 Sep;18(9):1397-404. Epub 2006 Aug 16.PMID: 16914507 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic dissection of V alpha 14J alpha 18 natural T cell number and function in autoimmune-prone mice.

Matsuki N, Stanic AK, Embers ME, Van Kaer L, Morel L, Joyce S.

J Immunol. 2003 Jun 1;170(11):5429-37.PMID: 12759418 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired SLAM-SLAM homotypic interaction between invariant NKT cells and dendritic cells affects differentiation of IL-4/IL-10-secreting NKT2 cells in nonobese diabetic mice.

Baev DV, Caielli S, Ronchi F, Coccia M, Facciotti F, Nichols KE, Falcone M.

J Immunol. 2008 Jul 15;181(2):869-77.PMID: 18606638 [PubMed - indexed for MEDLINE]Related articlesFree article