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    Results: 1 to 20 of 122

    1.

    Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?

    Brunmair B, Staniek K, Gras F, Scharf N, Althaym A, Clara R, Roden M, Gnaiger E, Nohl H, Waldhäusl W, Fürnsinn C.

    Diabetes. 2004 Apr;53(4):1052-9.PMID: 15047621 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Fenofibrate impairs rat mitochondrial function by inhibition of respiratory complex I.

    Brunmair B, Lest A, Staniek K, Gras F, Scharf N, Roden M, Nohl H, Waldhäusl W, Fürnsinn C.

    J Pharmacol Exp Ther. 2004 Oct;311(1):109-14. Epub 2004 May 27.PMID: 15166256 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Enhanced insulin-stimulated glycogen synthesis in response to insulin, metformin or rosiglitazone is associated with increased mRNA expression of GLUT4 and peroxisomal proliferator activator receptor gamma co-activator 1.

    Al-Khalili L, Forsgren M, Kannisto K, Zierath JR, Lönnqvist F, Krook A.

    Diabetologia. 2005 Jun;48(6):1173-9. Epub 2005 Apr 30.PMID: 15864539 [PubMed - indexed for MEDLINE]Related articles

    4.

    Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer.

    Hinke SA, Martens GA, Cai Y, Finsi J, Heimberg H, Pipeleers D, Van de Casteele M.

    Br J Pharmacol. 2007 Apr;150(8):1031-43. Epub 2007 Mar 5.PMID: 17339833 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Expression of uncoupling protein-3 mRNA in rat skeletal muscle is acutely stimulated by thiazolidinediones: an exercise-like effect?

    Brunmair B, Gras F, Wagner L, Artwohl M, Zierhut B, Waldhäusl W, Fürnsinn C.

    Diabetologia. 2004 Sep;47(9):1611-4. Epub 2004 Sep 2.PMID: 15349725 [PubMed - indexed for MEDLINE]Related articles

    6.

    Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain.

    Owen MR, Doran E, Halestrap AP.

    Biochem J. 2000 Jun 15;348 Pt 3:607-14.PMID: 10839993 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

    El-Mir MY, Nogueira V, Fontaine E, Avéret N, Rigoulet M, Leverve X.

    J Biol Chem. 2000 Jan 7;275(1):223-8.PMID: 10617608 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Anti-proliferative activity of oral anti-hyperglycemic agents on human vascular smooth muscle cells: thiazolidinediones (glitazones) have enhanced activity under high glucose conditions.

    Little PJ, Osman N, de Dios ST, Cemerlang N, Ballinger M, Nigro J.

    Cardiovasc Diabetol. 2007 Oct 28;6:33.PMID: 17963526 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin.

    Batandier C, Guigas B, Detaille D, El-Mir MY, Fontaine E, Rigoulet M, Leverve XM.

    J Bioenerg Biomembr. 2006 Feb;38(1):33-42.PMID: 16732470 [PubMed - indexed for MEDLINE]Related articles

    10.

    Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study.

    Guigas B, Detaille D, Chauvin C, Batandier C, De Oliveira F, Fontaine E, Leverve X.

    Biochem J. 2004 Sep 15;382(Pt 3):877-84.PMID: 15175014 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Differential inhibitory effects of antidiabetic drugs on arterial smooth muscle cell proliferation.

    Peuler JD, Phare SM, Iannucci AR, Hodorek MJ.

    Am J Hypertens. 1996 Feb;9(2):188-92.PMID: 8924270 [PubMed - indexed for MEDLINE]Related articles

    12.

    Disparate effects of antidiabetic drugs on arterial contraction.

    Peuler JD, Miller JA, Bourghli M, Zammam HY, Soltis EE, Sowers JR.

    Metabolism. 1997 Oct;46(10):1199-205.PMID: 9322807 [PubMed - indexed for MEDLINE]Related articles

    13.

    A comparison of the effects of thiazolidinediones and metformin on metabolic control in patients with type 2 diabetes mellitus.

    Seufert J, Lübben G, Dietrich K, Bates PC.

    Clin Ther. 2004 Jun;26(6):805-18. Review.PMID: 15262452 [PubMed - indexed for MEDLINE]Related articles

    14.

    Role and mechanism of rosiglitazone on the impairment of insulin secretion induced by free fatty acids on isolated rat islets.

    Tian JY, Li G, Gu YY, Zhang HL, Zhou WZ, Wang X, Zhu HD, Luo TH, Luo M.

    Chin Med J (Engl). 2006 Apr 5;119(7):574-80.PMID: 16620699 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Metabolic actions of metformin in the heart can occur by AMPK-independent mechanisms.

    Saeedi R, Parsons HL, Wambolt RB, Paulson K, Sharma V, Dyck JR, Brownsey RW, Allard MF.

    Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2497-506. Epub 2008 Mar 28.PMID: 18375721 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    [Therapeutic effects of insulin-sensitizing drugs on nonalcoholic fatty liver disease: experiment with rats]

    Zhang DM, Zhang GY, Wang T, Zhong HJ, Chen WK.

    Zhonghua Yi Xue Za Zhi. 2006 May 16;86(18):1279-83. Chinese. PMID: 16796890 [PubMed - indexed for MEDLINE]Related articles

    17.

    Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.

    Bachmakov I, Glaeser H, Fromm MF, König J.

    Diabetes. 2008 Jun;57(6):1463-9. Epub 2008 Feb 26.PMID: 18314419 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Progesterone impairs cell respiration and suppresses a compensatory increase in glucose transport in isolated rat skeletal muscle: a non-genomic mechanism contributing to metabolic adaptation to late pregnancy?

    Gras F, Brunmair B, Quarré L, Szöcs Z, Waldhäusl W, Fürnsinn C.

    Diabetologia. 2007 Dec;50(12):2544-52. Epub 2007 Oct 12.PMID: 17932647 [PubMed - indexed for MEDLINE]Related articles

    19.

    Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents fatty-acid-induced insulin resistance in the rat: comparison with metformin.

    Ye JM, Dzamko N, Cleasby ME, Hegarty BD, Furler SM, Cooney GJ, Kraegen EW.

    Diabetologia. 2004 Jul;47(7):1306-13. Epub 2004 Jul 1.PMID: 15232684 [PubMed - indexed for MEDLINE]Related articles

    20.

    Effects of insulin and metformin on glucose metabolism in rat vascular smooth muscle.

    Ofenstein JP, Dominguez LJ, Sowers JR, Sarnaik AP.

    Metabolism. 1999 Nov;48(11):1357-60.PMID: 10582541 [PubMed - indexed for MEDLINE]Related articles

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