PubMed

Interaction of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) with glucokinase activates glucose phosphorylation and glucose metabolism in insulin-producing cells.

Massa L, Baltrusch S, Okar DA, Lange AJ, Lenzen S, Tiedge M.

Diabetes. 2004 Apr;53(4):1020-9.PMID: 15047617 [PubMed - indexed for MEDLINE]Related articlesFree article

Improved metabolic stimulus for glucose-induced insulin secretion through GK and PFK-2/FBPase-2 coexpression in insulin-producing RINm5F cells.

Baltrusch S, Langer S, Massa L, Tiedge M, Lenzen S.

Endocrinology. 2006 Dec;147(12):5768-76. Epub 2006 Sep 15.PMID: 16980436 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells.

Arden C, Hampson LJ, Huang GC, Shaw JA, Aldibbiat A, Holliman G, Manas D, Khan S, Lange AJ, Agius L.

Biochem J. 2008 Apr 1;411(1):41-51.PMID: 18039179 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of glucokinase-binding protein epitopes by a phage-displayed peptide library. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel interaction partner.

Baltrusch S, Lenzen S, Okar DA, Lange AJ, Tiedge M.

J Biol Chem. 2001 Nov 23;276(47):43915-23. Epub 2001 Aug 24.PMID: 11522786 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular coordination of hepatic glucose metabolism by the 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase:glucokinase complex.

Smith WE, Langer S, Wu C, Baltrusch S, Okar DA.

Mol Endocrinol. 2007 Jun;21(6):1478-87. Epub 2007 Mar 20.PMID: 17374851 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenovirus-mediated overexpression of liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in gluconeogenic rat hepatoma cells. Paradoxical effect on Fru-2,6-P2 levels.

Argaud D, Lange AJ, Becker TC, Okar DA, el-Maghrabi MR, Newgard CB, Pilkis SJ.

J Biol Chem. 1995 Oct 13;270(41):24229-36.PMID: 7592629 [PubMed - indexed for MEDLINE]Related articlesFree article

Cloning and expression in Escherichia coli of a rat hepatoma cell cDNA coding for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Crepin KM, Darville MI, Michel A, Hue L, Rousseau GG.

Biochem J. 1989 Nov 15;264(1):151-60.PMID: 2557826 [PubMed - indexed for MEDLINE]Related articlesFree article

A potential role for fructose-2,6-bisphosphate in the stimulation of hepatic glucokinase gene expression.

Wu C, Okar DA, Stoeckman AK, Peng LJ, Herrera AH, Herrera JE, Towle HC, Lange AJ.

Endocrinology. 2004 Feb;145(2):650-8. Epub 2003 Nov 14.PMID: 14617577 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer.

Bando H, Atsumi T, Nishio T, Niwa H, Mishima S, Shimizu C, Yoshioka N, Bucala R, Koike T.

Clin Cancer Res. 2005 Aug 15;11(16):5784-92.PMID: 16115917 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of starvation on gene expression of regulatory enzymes of glycolysis/gluconeogenesis in genetically obese (fa/fa) Zucker rats.

Pérez JX, Manzano A, Tauler A, Bartrons R.

Int J Obes Relat Metab Disord. 1998 Jul;22(7):667-72.PMID: 9705027 [PubMed - indexed for MEDLINE]Related articles

An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism.

Futamura M, Hosaka H, Kadotani A, Shimazaki H, Sasaki K, Ohyama S, Nishimura T, Eiki J, Nagata Y.

J Biol Chem. 2006 Dec 8;281(49):37668-74. Epub 2006 Oct 6.PMID: 17028192 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose regulates the maximal velocities of glucokinase and glucose utilization in the immature fetal rat pancreatic islet.

Tu J, Tuch BE.

Diabetes. 1996 Aug;45(8):1068-75.PMID: 8690154 [PubMed - indexed for MEDLINE]Related articles

Cell-biological assessment of human glucokinase mutants causing maturity-onset diabetes of the young type 2 (MODY-2) or glucokinase-linked hyperinsulinaemia (GK-HI).

Burke CV, Buettger CW, Davis EA, McClane SJ, Matschinsky FM, Raper SE.

Biochem J. 1999 Sep 1;342 ( Pt 2):345-52.PMID: 10455021 [PubMed - indexed for MEDLINE]Related articlesFree article

Cloning, expression and chromosomal localization of a human testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene.

Manzano A, Pérez JX, Nadal M, Estivill X, Lange A, Bartrons R.

Gene. 1999 Mar 18;229(1-2):83-9.PMID: 10095107 [PubMed - indexed for MEDLINE]Related articles

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis.

Rider MH, Bertrand L, Vertommen D, Michels PA, Rousseau GG, Hue L.

Biochem J. 2004 Aug 1;381(Pt 3):561-79. Review.PMID: 15170386 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the N-terminal region in covalent modification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: comparison of phosphorylation and ADP-ribosylation.

Rosa JL, Pérez JX, Ventura F, Tauler A, Gil J, Shimoyama M, Pilkis SJ, Bartrons R.

Biochem J. 1995 Jul 1;309 ( Pt 1):119-25.PMID: 7619045 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular forms of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase expressed in rat skeletal muscle.

Crepin KM, De Cloedt M, Vertommen D, Foret D, Michel A, Rider MH, Rousseau GG, Hue L.

J Biol Chem. 1992 Oct 25;267(30):21698-704.PMID: 1328243 [PubMed - indexed for MEDLINE]Related articlesFree article

Study of the roles of Arg-104 and Arg-225 in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by site-directed mutagenesis.

Rider MH, Crepin KM, De Cloedt M, Bertrand L, Vertommen D, Hue L.

Biochem J. 1995 Jul 1;309 ( Pt 1):341-6.PMID: 7619077 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of either liver type or pancreatic beta cell type glucokinase via recombinant adenovirus enhances glucose oxidation in isolated rat hepatocytes.

Takeuchi H, Inoue Y, Ishihara H, Oka Y.

FEBS Lett. 1996 Sep 9;393(1):60-4.PMID: 8804424 [PubMed - indexed for MEDLINE]Related articles

6-Phosphofructo-2-kinase and fructose-2,6-bisphosphatase in Trypanosomatidae. Molecular characterization, database searches, modelling studies and evolutionary analysis.

Chevalier N, Bertrand L, Rider MH, Opperdoes FR, Rigden DJ, Michels PA.

FEBS J. 2005 Jul;272(14):3542-60.PMID: 16008555 [PubMed - indexed for MEDLINE]Related articlesFree article