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    Results: 1 to 20 of 326

    1.

    A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli.

    Roduit R, Nolan C, Alarcon C, Moore P, Barbeau A, Delghingaro-Augusto V, Przybykowski E, Morin J, Massé F, Massie B, Ruderman N, Rhodes C, Poitout V, Prentki M.

    Diabetes. 2004 Apr;53(4):1007-19.PMID: 15047616 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.

    Herrero L, Rubí B, Sebastián D, Serra D, Asins G, Maechler P, Prentki M, Hegardt FG.

    Diabetes. 2005 Feb;54(2):462-71.PMID: 15677504 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion.

    Prentki M, Vischer S, Glennon MC, Regazzi R, Deeney JT, Corkey BE.

    J Biol Chem. 1992 Mar 25;267(9):5802-10.PMID: 1556096 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells.

    Mulder H, Lu D, Finley J 4th, An J, Cohen J, Antinozzi PA, McGarry JD, Newgard CB.

    J Biol Chem. 2001 Mar 2;276(9):6479-84. Epub 2000 Dec 11.PMID: 11113153 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Fatty acid signaling in the beta-cell and insulin secretion.

    Nolan CJ, Madiraju MS, Delghingaro-Augusto V, Peyot ML, Prentki M.

    Diabetes. 2006 Dec;55 Suppl 2:S16-23. Review.PMID: 17130640 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis.

    Antinozzi PA, Segall L, Prentki M, McGarry JD, Newgard CB.

    J Biol Chem. 1998 Jun 26;273(26):16146-54.PMID: 9632669 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.

    Corkey BE, Deeney JT, Yaney GC, Tornheim K, Prentki M.

    J Nutr. 2000 Feb;130(2S Suppl):299S-304S. Review.PMID: 10721892 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic beta-cells.

    Corkey BE, Glennon MC, Chen KS, Deeney JT, Matschinsky FM, Prentki M.

    J Biol Chem. 1989 Dec 25;264(36):21608-12.PMID: 2689441 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling.

    Brun T, Roche E, Assimacopoulos-Jeannet F, Corkey BE, Kim KH, Prentki M.

    Diabetes. 1996 Feb;45(2):190-8.PMID: 8549864 [PubMed - indexed for MEDLINE]Related articles

    10.

    A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties.

    Skelly RH, Bollheimer LC, Wicksteed BL, Corkey BE, Rhodes CJ.

    Biochem J. 1998 Apr 15;331 ( Pt 2):553-61.PMID: 9531497 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?

    Prentki M, Corkey BE.

    Diabetes. 1996 Mar;45(3):273-83. Review.PMID: 8593930 [PubMed - indexed for MEDLINE]Related articles

    12.

    Content of CoA-esters in perifused rat islets stimulated by glucose and other fuels.

    Liang Y, Matschinsky FM.

    Diabetes. 1991 Mar;40(3):327-33.PMID: 1999274 [PubMed - indexed for MEDLINE]Related articles

    13.

    Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle.

    Alam N, Saggerson ED.

    Biochem J. 1998 Aug 15;334 ( Pt 1):233-41.PMID: 9693125 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling.

    Chen S, Ogawa A, Ohneda M, Unger RH, Foster DW, McGarry JD.

    Diabetes. 1994 Jul;43(7):878-83.PMID: 8013751 [PubMed - indexed for MEDLINE]Related articles

    15.

    Essential role of acetyl-CoA carboxylase in the glucose-induced insulin secretion in a pancreatic beta-cell line.

    Zhang S, Kim KH.

    Cell Signal. 1998 Jan;10(1):35-42.PMID: 9502115 [PubMed - indexed for MEDLINE]Related articles

    16.

    Augmentation of Ca2+-stimulated insulin release by glucose and long-chain fatty acids in rat pancreatic islets: free fatty acids mimic ATP-sensitive K+ channel-independent insulinotropic action of glucose.

    Komatsu M, Yajima H, Yamada S, Kaneko T, Sato Y, Yamauchi K, Hashizume K, Aizawa T.

    Diabetes. 1999 Aug;48(8):1543-9.PMID: 10426371 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion.

    Guay C, Madiraju SR, Aumais A, Joly E, Prentki M.

    J Biol Chem. 2007 Dec 7;282(49):35657-65. Epub 2007 Oct 10.PMID: 17928289 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Signal transduction mechanisms in nutrient-induced insulin secretion.

    Prentki M, Tornheim K, Corkey BE.

    Diabetologia. 1997 Jul;40 Suppl 2:S32-41. Review.PMID: 9248699 [PubMed - indexed for MEDLINE]Related articles

    19.

    Fatty acid metabolism and insulin secretion in pancreatic beta cells.

    Yaney GC, Corkey BE.

    Diabetologia. 2003 Oct;46(10):1297-312. Epub 2003 Sep 12. Review.PMID: 13680127 [PubMed - indexed for MEDLINE]Related articles

    20.

    Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta -cell.

    Roduit R, Morin J, Massé F, Segall L, Roche E, Newgard CB, Assimacopoulos-Jeannet F, Prentki M.

    J Biol Chem. 2000 Nov 17;275(46):35799-806.PMID: 10967113 [PubMed - indexed for MEDLINE]Related articlesFree article

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