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    Results: 1 to 20 of 117

    1.

    Differential recognition and activation thresholds in human autoreactive GAD-specific T-cells.

    Mallone R, Kochik SA, Laughlin EM, Gersuk VH, Reijonen H, Kwok WW, Nepom GT.

    Diabetes. 2004 Apr;53(4):971-7.PMID: 15047612 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes.

    Reijonen H, Mallone R, Heninger AK, Laughlin EM, Kochik SA, Falk B, Kwok WW, Greenbaum C, Nepom GT.

    Diabetes. 2004 Aug;53(8):1987-94.PMID: 15277377 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice.

    Patel SD, Cope AP, Congia M, Chen TT, Kim E, Fugger L, Wherrett D, Sonderstrup-McDevitt G.

    Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):8082-7.PMID: 9223318 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Soluble, dimeric HLA DR4-peptide chimeras: an approach for detection and immunoregulation of human type-1 diabetes.

    Preda I, McEvoy RC, Lin M, Bona CA, Rapaport R, Brumeanu TD, Casares S.

    Eur J Immunol. 2005 Sep;35(9):2762-75.PMID: 16106371 [PubMed - indexed for MEDLINE]Related articles

    5.

    Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects.

    Reijonen H, Novak EJ, Kochik S, Heninger A, Liu AW, Kwok WW, Nepom GT.

    Diabetes. 2002 May;51(5):1375-82.PMID: 11978633 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Processing and presentation of the islet autoantigen GAD by vascular endothelial cells promotes transmigration of autoreactive T-cells.

    Greening JE, Tree TI, Kotowicz KT, van Halteren AG, Roep BO, Klein NJ, Peakman M.

    Diabetes. 2003 Mar;52(3):717-25.PMID: 12606513 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    GAD-reactive T cells were mainly detected in autoimmune-related type 1 diabetic patients with HLA DR9.

    Itoh A, Shimada A, Kodama K, Morimoto J, Suzuki R, Oikawa Y, Irie J, Nakagawa Y, Shigihara T, Kanazawa Y, Okubo Y, Motohashi Y, Maruyama T, Saruta T.

    Ann N Y Acad Sci. 2004 Dec;1037:33-40.PMID: 15699491 [PubMed - indexed for MEDLINE]Related articles

    8.

    Complexity of human immune response profiles for CD4+ T cell epitopes from the diabetes autoantigen GAD65.

    Masewicz SA, Meldrum N, Gersuk V, Gaur L, Hagopian W, Moriarity L, Nepom GT.

    Autoimmunity. 2001;34(4):231-40.PMID: 11905849 [PubMed - indexed for MEDLINE]Related articles

    9.

    T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading.

    Ott PA, Dittrich MT, Herzog BA, Guerkov R, Gottlieb PA, Putnam AL, Durinovic-Bello I, Boehm BO, Tary-Lehmann M, Lehmann PV.

    J Clin Immunol. 2004 Jul;24(4):327-39.PMID: 15163889 [PubMed - indexed for MEDLINE]Related articles

    10.

    Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells.

    Kim SK, Tarbell KV, Sanna M, Vadeboncoeur M, Warganich T, Lee M, Davis M, McDevitt HO.

    Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14204-9. Epub 2004 Sep 20.PMID: 15381770 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects.

    Oling V, Marttila J, Ilonen J, Kwok WW, Nepom G, Knip M, Simell O, Reijonen H.

    J Autoimmun. 2005 Nov;25(3):235-43. Epub 2005 Nov 2. Erratum in: J Autoimmun. 2006 Aug;27(1):69. PMID: 16263242 [PubMed - indexed for MEDLINE]Related articles

    12.

    Modulation of antigen presentation by autoreactive B cell clones specific for GAD65 from a type I diabetic patient.

    Banga JP, Moore JK, Duhindan N, Madec AM, van Endert PM, Orgiazzi J, Endl J.

    Clin Exp Immunol. 2004 Jan;135(1):74-84.PMID: 14678267 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Active tolerance induction and prevention of autoimmune diabetes by immunogene therapy using recombinant adenoassociated virus expressing glutamic acid decarboxylase 65 peptide GAD(500-585).

    Han G, Li Y, Wang J, Wang R, Chen G, Song L, Xu R, Yu M, Wu X, Qian J, Shen B.

    J Immunol. 2005 Apr 15;174(8):4516-24.PMID: 15814672 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Comparative study of GAD65-specific CD4+ T cells in healthy and type 1 diabetic subjects.

    Danke NA, Yang J, Greenbaum C, Kwok WW.

    J Autoimmun. 2005 Dec;25(4):303-11. Epub 2005 Oct 24.PMID: 16249070 [PubMed - indexed for MEDLINE]Related articles

    15.

    Changes in autoreactive T cell avidity during type 1 diabetes development.

    Standifer NE, Burwell EA, Gersuk VH, Greenbaum CJ, Nepom GT.

    Clin Immunol. 2009 Sep;132(3):312-20. Epub 2009 May 23.PMID: 19482555 [PubMed - indexed for MEDLINE]Related articles

    16.

    Selection of aberrant class II restricted CD8+ T cells in NOD mice expressing a glutamic acid decarboxylase (GAD)65-specific T cell receptor transgene.

    Ranheim EA, Tarbell KV, Krogsgaard M, Mallet-Designe V, Teyton L, McDevitt HO, Weissman IL.

    Autoimmunity. 2004 Dec;37(8):555-67.PMID: 15763918 [PubMed - indexed for MEDLINE]Related articles

    17.

    Detection of GAD-reactive CD4+ cells in so-called "type 1B" diabetes.

    Shimada A, Kodama K, Morimoto J, Oikawa Y, Irie J, Nakagawa Y, Matsubara K, Maruyama T, Saruta T.

    Ann N Y Acad Sci. 2003 Nov;1005:378-86.PMID: 14679096 [PubMed - indexed for MEDLINE]Related articles

    18.

    Different diabetogenic potential of autoaggressive CD8+ clones associated with IFN-gamma-inducible protein 10 (CXC chemokine ligand 10) production but not cytokine expression, cytolytic activity, or homing characteristics.

    Ejrnaes M, Videbaek N, Christen U, Cooke A, Michelsen BK, von Herrath M.

    J Immunol. 2005 Mar 1;174(5):2746-55.PMID: 15728483 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas.

    Dai YD, Jensen KP, Lehuen A, Masteller EL, Bluestone JA, Wilson DB, Sercarz EE.

    J Immunol. 2005 Sep 15;175(6):3621-7.PMID: 16148106 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Controlling the controls: GAD65 autoreactive T cells in type 1 diabetes.

    Lernmark A.

    J Clin Invest. 2002 Apr;109(7):869-70. Review. No abstract available. PMID: 11927613 [PubMed - indexed for MEDLINE]Related articlesFree article

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