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    Results: 1 to 20 of 521

    1.

    Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient mice.

    Morton NM, Paterson JM, Masuzaki H, Holmes MC, Staels B, Fievet C, Walker BR, Flier JS, Mullins JJ, Seckl JR.

    Diabetes. 2004 Apr;53(4):931-8.PMID: 15047607 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    11beta-hydroxysteroid dehydrogenase type 1 and obesity.

    Morton NM, Seckl JR.

    Front Horm Res. 2008;36:146-64. Review.PMID: 18230901 [PubMed - indexed for MEDLINE]Related articles

    3.

    Down-regulation of adipose 11beta-hydroxysteroid dehydrogenase type 1 by high-fat feeding in mice: a potential adaptive mechanism counteracting metabolic disease.

    Morton NM, Ramage L, Seckl JR.

    Endocrinology. 2004 Jun;145(6):2707-12. Epub 2004 Mar 25.PMID: 15044372 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    A polygenic model of the metabolic syndrome with reduced circulating and intra-adipose glucocorticoid action.

    Morton NM, Densmore V, Wamil M, Ramage L, Nichol K, Bünger L, Seckl JR, Kenyon CJ.

    Diabetes. 2005 Dec;54(12):3371-8.PMID: 16306351 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Peroxisome proliferator-activated receptor-gamma ligands inhibit adipocyte 11beta -hydroxysteroid dehydrogenase type 1 expression and activity.

    Berger J, Tanen M, Elbrecht A, Hermanowski-Vosatka A, Moller DE, Wright SD, Thieringer R.

    J Biol Chem. 2001 Apr 20;276(16):12629-35. Epub 2001 Jan 22.PMID: 11278270 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Postnatal programming of glucocorticoid metabolism in rats modulates high-fat diet-induced regulation of visceral adipose tissue glucocorticoid exposure and sensitivity and adiponectin and proinflammatory adipokines gene expression in adulthood.

    Boullu-Ciocca S, Achard V, Tassistro V, Dutour A, Grino M.

    Diabetes. 2008 Mar;57(3):669-77. Epub 2007 Dec 5.PMID: 18057089 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice.

    Morton NM, Holmes MC, Fiévet C, Staels B, Tailleux A, Mullins JJ, Seckl JR.

    J Biol Chem. 2001 Nov 2;276(44):41293-300. Epub 2001 Aug 23.PMID: 11546766 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1.

    Ma LJ, Mao SL, Taylor KL, Kanjanabuch T, Guan Y, Zhang Y, Brown NJ, Swift LL, McGuinness OP, Wasserman DH, Vaughan DE, Fogo AB.

    Diabetes. 2004 Feb;53(2):336-46.PMID: 14747283 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Circulating resistin in lean, obese, and insulin-resistant mouse models: lack of association with insulinemia and glycemia.

    Lee JH, Bullen JW Jr, Stoyneva VL, Mantzoros CS.

    Am J Physiol Endocrinol Metab. 2005 Mar;288(3):E625-32. Epub 2004 Nov 2.PMID: 15522996 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.

    Vidal-Puig A, Jimenez-Liñan M, Lowell BB, Hamann A, Hu E, Spiegelman B, Flier JS, Moller DE.

    J Clin Invest. 1996 Jun 1;97(11):2553-61.PMID: 8647948 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Tissue-specific glucocorticoid reactivating enzyme, 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1)--a promising drug target for the treatment of metabolic syndrome.

    Masuzaki H, Flier JS.

    Curr Drug Targets Immune Endocr Metabol Disord. 2003 Dec;3(4):255-62. Review.PMID: 14683456 [PubMed - indexed for MEDLINE]Related articles

    12.

    Strain-specific response to beta 3-adrenergic receptor agonist treatment of diet-induced obesity in mice.

    Collins S, Daniel KW, Petro AE, Surwit RS.

    Endocrinology. 1997 Jan;138(1):405-13.PMID: 8977430 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    11beta-hydroxysteroid dehydrogenase type 1 mRNA is increased in both visceral and subcutaneous adipose tissue of obese patients.

    Desbriere R, Vuaroqueaux V, Achard V, Boullu-Ciocca S, Labuhn M, Dutour A, Grino M.

    Obesity (Silver Spring). 2006 May;14(5):794-8.PMID: 16855188 [PubMed - indexed for MEDLINE]Related articles

    14.

    PPAR-gamma activation mediates adipose depot-specific effects on gene expression and lipoprotein lipase activity: mechanisms for modulation of postprandial lipemia and differential adipose accretion.

    Laplante M, Sell H, MacNaul KL, Richard D, Berger JP, Deshaies Y.

    Diabetes. 2003 Feb;52(2):291-9.PMID: 12540599 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Expression of the mRNA coding for 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue from obese patients: an in situ hybridization study.

    Paulmyer-Lacroix O, Boullu S, Oliver C, Alessi MC, Grino M.

    J Clin Endocrinol Metab. 2002 Jun;87(6):2701-5.PMID: 12050237 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Role of glucocorticoids in the physiopathology of excessive fat deposition and insulin resistance.

    Asensio C, Muzzin P, Rohner-Jeanrenaud F.

    Int J Obes Relat Metab Disord. 2004 Dec;28 Suppl 4:S45-52. Review.PMID: 15592486 [PubMed - indexed for MEDLINE]Related articles

    17.

    Overexpression of 11beta-hydroxysteroid dehydrogenase-1 in adipose tissue is associated with acquired obesity and features of insulin resistance: studies in young adult monozygotic twins.

    Kannisto K, Pietiläinen KH, Ehrenborg E, Rissanen A, Kaprio J, Hamsten A, Yki-Järvinen H.

    J Clin Endocrinol Metab. 2004 Sep;89(9):4414-21.PMID: 15356040 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Adipocyte-specific glucocorticoid inactivation protects against diet-induced obesity.

    Kershaw EE, Morton NM, Dhillon H, Ramage L, Seckl JR, Flier JS.

    Diabetes. 2005 Apr;54(4):1023-31.PMID: 15793240 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    A transgenic model of visceral obesity and the metabolic syndrome.

    Masuzaki H, Paterson J, Shinyama H, Morton NM, Mullins JJ, Seckl JR, Flier JS.

    Science. 2001 Dec 7;294(5549):2166-70.PMID: 11739957 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 in obesity.

    Wake DJ, Walker BR.

    Endocrine. 2006 Feb;29(1):101-8. Review.PMID: 16622297 [PubMed - indexed for MEDLINE]Related articles

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