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    Results: 1 to 20 of 103

    1.

    Chronic effects of fatty acids on pancreatic beta-cell function: new insights from functional genomics.

    Biden TJ, Robinson D, Cordery D, Hughes WE, Busch AK.

    Diabetes. 2004 Feb;53 Suppl 1:S159-65. Review.PMID: 14749282 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Expression profiling of palmitate- and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic beta-cell function.

    Busch AK, Cordery D, Denyer GS, Biden TJ.

    Diabetes. 2002 Apr;51(4):977-87.PMID: 11916915 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    New insights into fatty acid modulation of pancreatic beta-cell function.

    Haber EP, Procópio J, Carvalho CR, Carpinelli AR, Newsholme P, Curi R.

    Int Rev Cytol. 2006;248:1-41. Review.PMID: 16487789 [PubMed - indexed for MEDLINE]Related articles

    4.

    Regulation of insulin secretion and expression of SUR1 gene by chronic exposure to free fatty acids in rat pancreatic beta cells.

    Yuan L, Deng X, Chen L, Zhou M.

    J Huazhong Univ Sci Technolog Med Sci. 2004;24(4):358-60, 364.PMID: 15587398 [PubMed - indexed for MEDLINE]Related articles

    5.

    beta-Cell function in subjects spanning the range from normal glucose tolerance to overt diabetes: a new analysis.

    Ferrannini E, Gastaldelli A, Miyazaki Y, Matsuda M, Mari A, DeFronzo RA.

    J Clin Endocrinol Metab. 2005 Jan;90(1):493-500. Epub 2004 Oct 13.PMID: 15483086 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Potential role of oral thiazolidinedione therapy in preserving beta-cell function in type 2 diabetes mellitus.

    Walter H, Lübben G.

    Drugs. 2005;65(1):1-13. Review.PMID: 15610048 [PubMed - indexed for MEDLINE]Related articles

    7.

    Long-Term exposure of INS-1 cells to cis and trans fatty acids influences insulin release and fatty acid oxidation differentially.

    Alstrup KK, Brock B, Hermansen K.

    Metabolism. 2004 Sep;53(9):1158-65.PMID: 15334378 [PubMed - indexed for MEDLINE]Related articles

    8.

    Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.

    Joseph JW, Koshkin V, Saleh MC, Sivitz WI, Zhang CY, Lowell BB, Chan CB, Wheeler MB.

    J Biol Chem. 2004 Dec 3;279(49):51049-56. Epub 2004 Sep 23.PMID: 15448158 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Induction of beta-cell rest by a Kir6.2/SUR1-selective K(ATP)-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose.

    Ritzel RA, Hansen JB, Veldhuis JD, Butler PC.

    J Clin Endocrinol Metab. 2004 Feb;89(2):795-805.PMID: 14764798 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    [Anatomical and functional plasticity of pancreatic beta-cells and type 2 diabetes]

    Cerasi E, Ktorza A.

    Med Sci (Paris). 2007 Oct;23(10):885-94. Review. French. PMID: 17937902 [PubMed - indexed for MEDLINE]Related articles

    11.

    Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling.

    Nolan CJ, Leahy JL, Delghingaro-Augusto V, Moibi J, Soni K, Peyot ML, Fortier M, Guay C, Lamontagne J, Barbeau A, Przybytkowski E, Joly E, Masiello P, Wang S, Mitchell GA, Prentki M.

    Diabetologia. 2006 Sep;49(9):2120-30. Epub 2006 Jul 26.PMID: 16868750 [PubMed - indexed for MEDLINE]Related articles

    12.

    Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo.

    Oprescu AI, Bikopoulos G, Naassan A, Allister EM, Tang C, Park E, Uchino H, Lewis GF, Fantus IG, Rozakis-Adcock M, Wheeler MB, Giacca A.

    Diabetes. 2007 Dec;56(12):2927-37. Epub 2007 Aug 23.PMID: 17717282 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Non-esterified fatty acids are deleterious for human pancreatic islet function at physiological glucose concentration.

    Dubois M, Kerr-Conte J, Gmyr V, Bouckenooghe T, Muharram G, D'Herbomez M, Martin-Ponthieu A, Vantyghem MC, Vandewalle B, Pattou F.

    Diabetologia. 2004 Mar;47(3):463-9. Epub 2004 Feb 13.PMID: 14968298 [PubMed - indexed for MEDLINE]Related articles

    14.

    Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion.

    Noushmehr H, D'Amico E, Farilla L, Hui H, Wawrowsky KA, Mlynarski W, Doria A, Abumrad NA, Perfetti R.

    Diabetes. 2005 Feb;54(2):472-81.PMID: 15677505 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Effects of short-term experimental insulin resistance and family history of diabetes on pancreatic beta-cell function in nondiabetic individuals.

    Rasouli N, Hale T, Kahn SE, Spencer HJ, Elbein SC.

    J Clin Endocrinol Metab. 2005 Oct;90(10):5825-33. Epub 2005 Aug 9.PMID: 16091496 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes.

    Tripathy D, Eriksson KF, Orho-Melander M, Fredriksson J, Ahlqvist G, Groop L.

    Diabetologia. 2004 May;47(5):782-93. Epub 2004 Apr 28.PMID: 15114470 [PubMed - indexed for MEDLINE]Related articles

    17.

    Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet.

    Fex M, Nitert MD, Wierup N, Sundler F, Ling C, Mulder H.

    Diabetologia. 2007 Jan;50(1):74-83. Epub 2006 Nov 9.PMID: 17093947 [PubMed - indexed for MEDLINE]Related articles

    18.

    [And what about diabetes?]

    Cerasi E.

    Bull Acad Natl Med. 2007 Apr-May;191(4-5):941-3; discussion 943. French. PMID: 18225448 [PubMed - indexed for MEDLINE]Related articles

    19.

    Differential gene expression between Zucker Fatty rats and Zucker Diabetic Fatty rats: a potential role for the immediate-early gene Egr-1 in regulation of beta cell proliferation.

    Garnett KE, Chapman P, Chambers JA, Waddell ID, Boam DS.

    J Mol Endocrinol. 2005 Aug;35(1):13-25.PMID: 16087718 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Coordinate changes in plasma glucose and pancreatic beta-cell function in Latino women at high risk for type 2 diabetes.

    Xiang AH, Wang C, Peters RK, Trigo E, Kjos SL, Buchanan TA.

    Diabetes. 2006 Apr;55(4):1074-9.PMID: 16567531 [PubMed - indexed for MEDLINE]Related articlesFree article

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