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    Results: 1 to 20 of 113

    1.

    Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes.

    Robertson RP, Harmon J, Tran PO, Poitout V.

    Diabetes. 2004 Feb;53 Suppl 1:S119-24. Review.PMID: 14749276 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection.

    Robertson RP, Harmon J, Tran PO, Tanaka Y, Takahashi H.

    Diabetes. 2003 Mar;52(3):581-7. Review.PMID: 12606496 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity.

    Poitout V, Robertson RP.

    Endocrinology. 2002 Feb;143(2):339-42. Review.PMID: 11796484 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Role of oxidative stress in pancreatic beta-cell dysfunction.

    Kajimoto Y, Kaneto H.

    Ann N Y Acad Sci. 2004 Apr;1011:168-76.PMID: 15126294 [PubMed - indexed for MEDLINE]Related articles

    5.

    Chronic oxidative stress as a mechanism for glucose toxicity of the beta cell in type 2 diabetes.

    Robertson R, Zhou H, Zhang T, Harmon JS.

    Cell Biochem Biophys. 2007;48(2-3):139-46.PMID: 17709883 [PubMed - indexed for MEDLINE]Related articles

    6.

    [Anatomical and functional plasticity of pancreatic beta-cells and type 2 diabetes]

    Cerasi E, Ktorza A.

    Med Sci (Paris). 2007 Oct;23(10):885-94. Review. French. PMID: 17937902 [PubMed - indexed for MEDLINE]Related articles

    7.

    Diabetes, glucose toxicity, and oxidative stress: A case of double jeopardy for the pancreatic islet beta cell.

    Robertson RP, Harmon JS.

    Free Radic Biol Med. 2006 Jul 15;41(2):177-84. Epub 2006 May 4. Review.PMID: 16814095 [PubMed - indexed for MEDLINE]Related articles

    8.

    Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.

    Ihara Y, Toyokuni S, Uchida K, Odaka H, Tanaka T, Ikeda H, Hiai H, Seino Y, Yamada Y.

    Diabetes. 1999 Apr;48(4):927-32.PMID: 10102716 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Protection of pancreatic beta-cells: is it feasible?

    Bonora E.

    Nutr Metab Cardiovasc Dis. 2008 Jan;18(1):74-83. Review.PMID: 18096375 [PubMed - indexed for MEDLINE]Related articles

    10.

    Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?

    Evans JL, Goldfine ID, Maddux BA, Grodsky GM.

    Diabetes. 2003 Jan;52(1):1-8. Review.PMID: 12502486 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Involvement of oxidative stress in the pathogenesis of diabetes.

    Kaneto H, Katakami N, Kawamori D, Miyatsuka T, Sakamoto K, Matsuoka TA, Matsuhisa M, Yamasaki Y.

    Antioxid Redox Signal. 2007 Mar;9(3):355-66. Review.PMID: 17184181 [PubMed - indexed for MEDLINE]Related articles

    12.

    Prevention of oxidative stress by adenoviral overexpression of glutathione-related enzymes in pancreatic islets.

    Robertson RP, Tanaka Y, Takahashi H, Tran PO, Harmon JS.

    Ann N Y Acad Sci. 2005 Jun;1043:513-20.PMID: 16037273 [PubMed - indexed for MEDLINE]Related articles

    13.

    Pancreatic islet beta-cell and oxidative stress: the importance of glutathione peroxidase.

    Robertson RP, Harmon JS.

    FEBS Lett. 2007 Jul 31;581(19):3743-8. Epub 2007 Apr 9.PMID: 17433304 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Can exercise minimize postprandial oxidative stress in patients with type 2 diabetes?

    Tucker PS, Fisher-Wellman K, Bloomer RJ.

    Curr Diabetes Rev. 2008 Nov;4(4):309-19. Review.PMID: 18991599 [PubMed - indexed for MEDLINE]Related articles

    15.

    Insulin secretion defects of human type 2 diabetic islets are corrected in vitro by a new reactive oxygen species scavenger.

    Lupi R, Del Guerra S, Mancarella R, Novelli M, Valgimigli L, Pedulli GF, Paolini M, Soleti A, Filipponi F, Mosca F, Boggi U, Del Prato S, Masiello P, Marchetti P.

    Diabetes Metab. 2007 Nov;33(5):340-5. Epub 2007 Jul 9.PMID: 17616474 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Potential role of oral thiazolidinedione therapy in preserving beta-cell function in type 2 diabetes mellitus.

    Walter H, Lübben G.

    Drugs. 2005;65(1):1-13. Review.PMID: 15610048 [PubMed - indexed for MEDLINE]Related articles

    17.

    [Oxidative stress induces cellular damage and dysfunction of pancreatic beta-cells in type 2 diabetes]

    Ihara Y.

    Nippon Rinsho. 2002 Jul;60 Suppl 7:498-503. Review. Japanese. No abstract available. PMID: 12238089 [PubMed - indexed for MEDLINE]Related articles

    18.

    Effects of Nigella sativa on oxidative stress and beta-cell damage in streptozotocin-induced diabetic rats.

    Kanter M, Coskun O, Korkmaz A, Oter S.

    Anat Rec A Discov Mol Cell Evol Biol. 2004 Jul;279(1):685-91.PMID: 15224410 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Quercetin, a flavonoid antioxidant, prevents and protects streptozotocin-induced oxidative stress and beta-cell damage in rat pancreas.

    Coskun O, Kanter M, Korkmaz A, Oter S.

    Pharmacol Res. 2005 Feb;51(2):117-23.PMID: 15629256 [PubMed - indexed for MEDLINE]Related articles

    20.

    Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress.

    Rolo AP, Palmeira CM.

    Toxicol Appl Pharmacol. 2006 Apr 15;212(2):167-78. Epub 2006 Feb 20. Review.PMID: 16490224 [PubMed - indexed for MEDLINE]Related articles

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