PubMed

Genetic factors and insulin secretion: gene variants in the IGF genes.

't Hart LM, Fritsche A, Rietveld I, Dekker JM, Nijpels G, Machicao F, Stumvoll M, van Duijn CM, Häring HU, Heine RJ, Maassen JA, van Haeften TW.

Diabetes. 2004 Feb;53 Suppl 1:S26-30.PMID: 14749262 [PubMed - indexed for MEDLINE]Related articlesFree article

Variations in insulin secretion in carriers of gene variants in IRS-1 and -2.

't Hart LM, Nijpels G, Dekker JM, Maassen JA, Heine RJ, van Haeften TW.

Diabetes. 2002 Mar;51(3):884-7.PMID: 11872698 [PubMed - indexed for MEDLINE]Related articlesFree article

Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus.

Rasmussen SK, Lautier C, Hansen L, Echwald SM, Hansen T, Ekstrøm CT, Urhammer SA, Borch-Johnsen K, Grigorescu F, Smith RJ, Pedersen O.

J Clin Endocrinol Metab. 2000 Apr;85(4):1606-10.PMID: 10770205 [PubMed - indexed for MEDLINE]Related articlesFree article

Variations in insulin secretion in carriers of the E23K variant in the KIR6.2 subunit of the ATP-sensitive K(+) channel in the beta-cell.

't Hart LM, van Haeften TW, Dekker JM, Bot M, Heine RJ, Maassen JA.

Diabetes. 2002 Oct;51(10):3135-8.PMID: 12351459 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps.

Groenewoud MJ, Dekker JM, Fritsche A, Reiling E, Nijpels G, Heine RJ, Maassen JA, Machicao F, Schäfer SA, Häring HU, 't Hart LM, van Haeften TW.

Diabetologia. 2008 Sep;51(9):1659-63. Epub 2008 Jul 11.PMID: 18618095 [PubMed - indexed for MEDLINE]Related articles

Insulin-like growth factor-1 genotype predicts breast volume after pregnancy and hormonal contraception and is associated with circulating insulin-like growth factor-1 levels: implications for risk of early-onset breast cancer in young women from hereditary breast cancer families.

Jernström H, Sandberg T, Bågeman E, Borg A, Olsson H.

Int J Gynecol Cancer. 2006;16 Suppl 2:497.PMID: 17010055 [PubMed - indexed for MEDLINE]Related articles

Impaired beta-cell function and inadequate compensatory increases in beta-cell mass after intrauterine growth restriction in sheep.

Gatford KL, Mohammad SN, Harland ML, De Blasio MJ, Fowden AL, Robinson JS, Owens JA.

Endocrinology. 2008 Oct;149(10):5118-27. Epub 2008 Jun 5.PMID: 18535100 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin sensitivity and secretion in normal children related to size at birth, postnatal growth, and plasma insulin-like growth factor-I levels.

Ong KK, Petry CJ, Emmett PM, Sandhu MS, Kiess W, Hales CN, Ness AR, Dunger DB; ALSPAC study team.

Diabetologia. 2004 Jun;47(6):1064-70. Epub 2004 May 20.PMID: 15156313 [PubMed - indexed for MEDLINE]Related articles

A putative functional polymorphism in the IGF-I gene: association studies with type 2 diabetes, adult height, glucose tolerance, and fetal growth in U.K. populations.

Frayling TM, Hattersley AT, McCarthy A, Holly J, Mitchell SM, Gloyn AL, Owen K, Davies D, Smith GD, Ben-Shlomo Y.

Diabetes. 2002 Jul;51(7):2313-6.PMID: 12086966 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the polycystic ovary syndrome with genomic variants related to insulin resistance, type 2 diabetes mellitus, and obesity.

San Millán JL, Cortón M, Villuendas G, Sancho J, Peral B, Escobar-Morreale HF.

J Clin Endocrinol Metab. 2004 Jun;89(6):2640-6.PMID: 15181035 [PubMed - indexed for MEDLINE]Related articlesFree article

A polymorphic CA repeat in the IGF-I gene is associated with gender-specific differences in body height, but has no effect on the secular trend in body height.

Rietveld I, Janssen JA, van Rossum EF, Houwing-Duistermaat JJ, Rivadeneira F, Hofman A, Pols HA, van Duijn CM, Lamberts SW.

Clin Endocrinol (Oxf). 2004 Aug;61(2):195-203.PMID: 15272914 [PubMed - indexed for MEDLINE]Related articles

Association between an IGF-I gene polymorphism and body fatness: differences between generations.

Voorhoeve PG, van Rossum EF, Te Velde SJ, Koper JW, Kemper HC, Lamberts SW, de Waal HA.

Eur J Endocrinol. 2006 Mar;154(3):379-88.PMID: 16498050 [PubMed - indexed for MEDLINE]Related articlesFree article

The relationship in Japanese infants between a genetic polymorphism in the promoter region of the insulin-like growth factor I gene and the plasma level.

Kinoshita Y, Kizaki Z, Ishihara Y, Nakajima H, Adachi S, Kosaka K, Kinugasa A, Sugimoto T.

Neonatology. 2007;92(2):116-9. Epub 2007 Mar 23.PMID: 17377412 [PubMed - indexed for MEDLINE]Related articles

A common polymorphism in the promoter of the IGF-I gene associates with increased fasting serum triglyceride levels in glucose-tolerant subjects.

Nielsen EM, Hansen L, Lajer M, Andersen KL, Echwald SM, Urhammer SA, Hansen T, Pedersen O.

Clin Biochem. 2004 Aug;37(8):660-5.PMID: 15302607 [PubMed - indexed for MEDLINE]Related articles

IGF-I gene promoter polymorphism is a predictor of survival after myocardial infarction in patients with type 2 diabetes.

Yazdanpanah M, Sayed-Tabatabaei FA, Janssen JA, Rietveld I, Hofman A, Stijnen T, Pols HA, Lamberts SW, Witteman JC, van Duijn CM.

Eur J Endocrinol. 2006 Nov;155(5):751-6.PMID: 17062892 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum insulin-like growth factor-I levels and potential risk of type 2 diabetes.

Dunger DB, Ong KK, Sandhu MS.

Horm Res. 2003;60 Suppl 3:131-5. Review.PMID: 14671410 [PubMed - indexed for MEDLINE]Related articles

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.

Grarup N, Rose CS, Andersson EA, Andersen G, Nielsen AL, Albrechtsen A, Clausen JO, Rasmussen SS, Jørgensen T, Sandbaek A, Lauritzen T, Schmitz O, Hansen T, Pedersen O.

Diabetes. 2007 Dec;56(12):3105-11. Epub 2007 Sep 7.PMID: 17827400 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis of the IGF1 gene with childhood growth, IGF-1 concentrations and type 1 diabetes.

Vella A, Bouatia-Naji N, Heude B, Cooper JD, Lowe CE, Petry C, Ring SM, Dunger DB, Todd JA, Ong KK.

Diabetologia. 2008 May;51(5):811-5. Epub 2008 Mar 4.PMID: 18317720 [PubMed - indexed for MEDLINE]Related articlesFree article

The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: the Rotterdam Study.

Rivadeneira F, Houwing-Duistermaat JJ, Beck TJ, Janssen JA, Hofman A, Pols HA, Van Duijn CM, Uitterlinden AG.

J Bone Miner Res. 2004 Aug;19(8):1280-90. Epub 2004 Apr 12.PMID: 15231015 [PubMed - indexed for MEDLINE]Related articles

Pancreatic islet-specific expression of an insulin-like growth factor-I transgene compensates islet cell growth in growth hormone receptor gene-deficient mice.

Guo Y, Lu Y, Houle D, Robertson K, Tang Z, Kopchick JJ, Liu YL, Liu JL.

Endocrinology. 2005 Jun;146(6):2602-9. Epub 2005 Feb 24.PMID: 15731363 [PubMed - indexed for MEDLINE]Related articlesFree article