PubMed

Haplotype tag single nucleotide polymorphism analysis of the human orthologues of the rat type 1 diabetes genes Ian4 (Lyp/Iddm1) and Cblb.

Payne F, Smyth DJ, Pask R, Barratt BJ, Cooper JD, Twells RC, Walker NM, Lam AC, Smink LJ, Nutland S, Rance HE, Todd JA.

Diabetes. 2004 Feb;53(2):505-9.PMID: 14747305 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphic variation in the CBLB gene in human type 1 diabetes.

Kosoy R, Yokoi N, Seino S, Concannon P.

Genes Immun. 2004 May;5(3):232-5.PMID: 14961073 [PubMed - indexed for MEDLINE]Related articles

Cblb is a major susceptibility gene for rat type 1 diabetes mellitus.

Yokoi N, Komeda K, Wang HY, Yano H, Kitada K, Saitoh Y, Seino Y, Yasuda K, Serikawa T, Seino S.

Nat Genet. 2002 Aug;31(4):391-4. Epub 2002 Jul 15.PMID: 12118252 [PubMed - indexed for MEDLINE]Related articles

CBLB variants in type 1 diabetes and their genetic interaction with CTLA4.

Bergholdt R, Taxvig C, Eising S, Nerup J, Pociot F.

J Leukoc Biol. 2005 Apr;77(4):579-85. Epub 2005 Jan 3.PMID: 15629882 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a major gene responsible for type 1 diabetes in the Komeda diabetes-prone rat.

Yokoi N.

Exp Anim. 2005 Apr;54(2):111-5. Review.PMID: 15897618 [PubMed - indexed for MEDLINE]Related articlesFree article

The diabetes-prone BB rat carries a frameshift mutation in Ian4, a positional candidate of Iddm1.

Hornum L, Rømer J, Markholst H.

Diabetes. 2002 Jun;51(6):1972-9.PMID: 12031988 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic reconstitution of autoimmune type 1 diabetes with two major susceptibility genes in the rat.

Yokoi N, Hayashi C, Fujiwara Y, Wang HY, Seino S.

Diabetes. 2007 Feb;56(2):506-12.PMID: 17259398 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene.

MacMurray AJ, Moralejo DH, Kwitek AE, Rutledge EA, Van Yserloo B, Gohlke P, Speros SJ, Snyder B, Schaefer J, Bieg S, Jiang J, Ettinger RA, Fuller J, Daniels TL, Pettersson A, Orlebeke K, Birren B, Jacob HJ, Lander ES, Lernmark A.

Genome Res. 2002 Jul;12(7):1029-39.PMID: 12097339 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction analysis of the CBLB and CTLA4 genes in type 1 diabetes.

Payne F, Cooper JD, Walker NM, Lam AC, Smink LJ, Nutland S, Stevens HE, Hutchings J, Todd JA.

J Leukoc Biol. 2007 Mar;81(3):581-3. Epub 2007 Jan 5.PMID: 17209142 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes-prone and diabetes-resistant BB rats share a common major diabetes susceptibility locus, iddm4: additional evidence for a "universal autoimmunity locus" on rat chromosome 4.

Martin AM, Maxson MN, Leif J, Mordes JP, Greiner DL, Blankenhorn EP.

Diabetes. 1999 Nov;48(11):2138-44.PMID: 10535446 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus.

Mordes JP, Cort L, Norowski E, Leif J, Fuller JM, Lernmark A, Greiner DL, Blankenhorn EP.

Mamm Genome. 2009 Mar;20(3):162-9. Epub 2009 Feb 10.PMID: 19205800 [PubMed - indexed for MEDLINE]Related articles

Establishment and characterization of the Komeda diabetes-prone rat as a segregating inbred strain.

Yokoi N, Namae M, Fuse M, Wang HY, Hirata T, Seino S, Komeda K.

Exp Anim. 2003 Jul;52(4):295-301.PMID: 14562605 [PubMed - indexed for MEDLINE]Related articlesFree article

Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes.

Maier LM, Smyth DJ, Vella A, Payne F, Cooper JD, Pask R, Lowe C, Hulme J, Smink LJ, Fraser H, Moule C, Hunter KM, Chamberlain G, Walker N, Nutland S, Undlien DE, Rønningen KS, Guja C, Ionescu-Tîrgoviste C, Savage DA, Strachan DP, Peterson LB, Todd JA, Wicker LS, Twells RC.

BMC Genet. 2005 Feb 18;6(1):9.PMID: 15720714 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for linkage on chromosome 4p16.1 in Type 1 diabetes Danish families and complete mutation scanning of the WFS1 (Wolframin) gene.

Larsen ZM, Johannesen J, Kristiansen OP, Nerup J, Pociot F; Danish IDDM Epidemiology and Genetics Group; Danish Study Group of IDDM in Childhood.

Diabet Med. 2004 Mar;21(3):218-22.PMID: 15008830 [PubMed - indexed for MEDLINE]Related articles

Systematic search for single nucleotide polymorphisms in a lymphoid tyrosine phosphatase gene (PTPN22): association between a promoter polymorphism and type 1 diabetes in Asian populations.

Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, Tanaka S, Kanazawa Y, Lee I, Eguchi K.

Am J Med Genet A. 2006 Mar 15;140(6):586-93. Erratum in: Am J Med Genet A. 2007 Aug 1;143(15):18212-3. Uga, Mho [corrected to Uga, Miho]. PMID: 16470599 [PubMed - indexed for MEDLINE]Related articles

Cost-effective analysis of candidate genes using htSNPs: a staged approach.

Lowe CE, Cooper JD, Chapman JM, Barratt BJ, Twells RC, Green EA, Savage DA, Guja C, Ionescu-Tîrgovişte C, Tuomilehto-Wolf E, Tuomilehto J, Todd JA, Clayton DG.

Genes Immun. 2004 Jun;5(4):301-5.PMID: 15029236 [PubMed - indexed for MEDLINE]Related articles

Isolation and characterization of the human AKT1 gene, identification of 13 single nucleotide polymorphisms (SNPs), and their lack of association with Type II diabetes.

Matsubara A, Wasson JC, Donelan SS, Welling CM, Glaser B, Permutt MA.

Diabetologia. 2001 Jul;44(7):910-3.PMID: 11508278 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in the multifunctional transcription factor Yy1 and type 1 diabetes mellitus in the BB rat.

Klöting N, Klöting I.

Mol Genet Metab. 2004 Jul;82(3):255-9.PMID: 15234341 [PubMed - indexed for MEDLINE]Related articles

Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs.

Brand OJ, Lowe CE, Heward JM, Franklyn JA, Cooper JD, Todd JA, Gough SC.

Clin Endocrinol (Oxf). 2007 Apr;66(4):508-12.PMID: 17371467 [PubMed - indexed for MEDLINE]Related articles

Type 1 diabetes in the BB rat: a polygenic disease.

Wallis RH, Wang K, Marandi L, Hsieh E, Ning T, Chao GY, Sarmiento J, Paterson AD, Poussier P.

Diabetes. 2009 Apr;58(4):1007-17. Epub 2009 Jan 23.PMID: 19168599 [PubMed - indexed for MEDLINE]Related articlesFree article