PubMed

Asp299Gly and Thr399Ile genotypes of the TLR4 gene are associated with a reduced prevalence of diabetic neuropathy in patients with type 2 diabetes.

Rudofsky G Jr, Reismann P, Witte S, Humpert PM, Isermann B, Chavakis T, Tafel J, Nosikov VV, Hamann A, Nawroth P, Bierhaus A.

Diabetes Care. 2004 Jan;27(1):179-83.PMID: 14693986 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease.

Brand S, Staudinger T, Schnitzler F, Pfennig S, Hofbauer K, Dambacher J, Seiderer J, Tillack C, Konrad A, Crispin A, Göke B, Lohse P, Ochsenkühn T.

Inflamm Bowel Dis. 2005 Jul;11(7):645-52.PMID: 15973118 [PubMed - indexed for MEDLINE]Related articles

Lack of association between polymorphisms of the toll-like receptor 4 gene and cerebral ischemia.

Reismann P, Lichy C, Rudofsky G, Humpert PM, Genius J, Si TD, Dörfer C, Grau AJ, Hamann A, Hacke W, Nawroth PP, Bierhaus A.

J Neurol. 2004 Jul;251(7):853-8.PMID: 15258789 [PubMed - indexed for MEDLINE]Related articles

Functional polymorphisms of UCP2 and UCP3 are associated with a reduced prevalence of diabetic neuropathy in patients with type 1 diabetes.

Rudofsky G Jr, Schroedter A, Schlotterer A, Voron'ko OE, Schlimme M, Tafel J, Isermann BH, Humpert PM, Morcos M, Bierhaus A, Nawroth PP, Hamann A.

Diabetes Care. 2006 Jan;29(1):89-94.PMID: 16373902 [PubMed - indexed for MEDLINE]Related articlesFree article

Toll-like receptor 4 gene polymorphisms and preeclampsia: lack of association in a Caucasian population.

Molvarec A, Jermendy A, Kovács M, Prohászka Z, Rigó J Jr.

Hypertens Res. 2008 May;31(5):859-64.PMID: 18712040 [PubMed - indexed for MEDLINE]Related articles

Toll-like receptor 4 gene polymorphism and early onset of diabetic retinopathy in patients with type 2 diabetes.

Buraczynska M, Baranowicz-Gaszczyk I, Tarach J, Ksiazek A.

Hum Immunol. 2009 Feb;70(2):121-4. Epub 2009 Jan 7.PMID: 19135114 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms of TLR4: rapid genotyping and reduced response to lipopolysaccharide of TLR4 mutant alleles.

Schmitt C, Humeny A, Becker CM, Brune K, Pahl A.

Clin Chem. 2002 Oct;48(10):1661-7.PMID: 12324481 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.

Ameziane N, Beillat T, Verpillat P, Chollet-Martin S, Aumont MC, Seknadji P, Lamotte M, Lebret D, Ollivier V, de Prost D.

Arterioscler Thromb Vasc Biol. 2003 Dec;23(12):e61-4. Epub 2003 Oct 16.PMID: 14563652 [PubMed - indexed for MEDLINE]Related articlesFree article

TLR4 Asp299Gly and Thr399Ile polymorphisms are very rare in the Chinese population.

Hang J, Zhou W, Zhang H, Sun B, Dai H, Su L, Christiani DC.

J Endotoxin Res. 2004;10(4):238-40.PMID: 15373967 [PubMed - indexed for MEDLINE]Related articles

Rarity of TLR4 Asp299Gly and Thr399Ile polymorphisms in the Korean population.

Kim YS, Hwang YJ, Kim SY, Yang SM, Lee KY, Park IeB.

Yonsei Med J. 2008 Feb 29;49(1):58-62.PMID: 18306470 [PubMed - indexed for MEDLINE]Related articlesFree article

Gingival epithelial cells heterozygous for Toll-like receptor 4 polymorphisms Asp299Gly and Thr399ile are hypo-responsive to Porphyromonas gingivalis.

Kinane DF, Shiba H, Stathopoulou PG, Zhao H, Lappin DF, Singh A, Eskan MA, Beckers S, Waigel S, Alpert B, Knudsen TB.

Genes Immun. 2006 Apr;7(3):190-200.PMID: 16437123 [PubMed - indexed for MEDLINE]Related articles

A M55V polymorphism in the SUMO4 gene is associated with a reduced prevalence of diabetic retinopathy in patients with Type 1 diabetes.

Rudofsky G Jr, Schlotterer A, Humpert PM, Tafel J, Morcos M, Nawroth PP, Bierhaus A, Hamann A.

Exp Clin Endocrinol Diabetes. 2008 Jan;116(1):14-7. Epub 2007 Oct 9.PMID: 17926234 [PubMed - indexed for MEDLINE]Related articles

Toll-like receptor (TLR) 2 and 4 mutations in periodontal disease.

Folwaczny M, Glas J, Török HP, Limbersky O, Folwaczny C.

Clin Exp Immunol. 2004 Feb;135(2):330-5.PMID: 14738464 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between the Asp299Gly polymorphisms in the Toll-like receptor 4 and premature births in the Finnish population.

Lorenz E, Hallman M, Marttila R, Haataja R, Schwartz DA.

Pediatr Res. 2002 Sep;52(3):373-6.PMID: 12193670 [PubMed - indexed for MEDLINE]Related articles

TLR2 Arg753Gly, TLR4 Asp299Gly and Thr399Ile gene polymorphisms are not associated with chronic periodontitis in a Turkish population.

Berdeli A, Emingil G, Han Saygan B, Gürkan A, Atilla G, Köse T, Baylas H.

J Clin Periodontol. 2007 Jul;34(7):551-7.PMID: 17555409 [PubMed - indexed for MEDLINE]Related articles

Association between Toll-like receptor 4 and inflammatory bowel disease.

Oostenbrug LE, Drenth JP, de Jong DJ, Nolte IM, Oosterom E, van Dullemen HM, van der Linde K, te Meerman GJ, van der Steege G, Kleibeuker JH, Jansen PL.

Inflamm Bowel Dis. 2005 Jun;11(6):567-75.PMID: 15905704 [PubMed - indexed for MEDLINE]Related articles

Toll-like receptor 4 gene polymorphisms and susceptibility to juvenile idiopathic arthritis.

Lamb R, Zeggini E, Thomson W, Donn R.

Ann Rheum Dis. 2005 May;64(5):767-9. Epub 2004 Oct 21.PMID: 15498795 [PubMed - indexed for MEDLINE]Related articlesFree article

Has toll-like receptor 4 been prematurely dismissed as an inflammatory bowel disease gene? Association study combined with meta-analysis shows strong evidence for association.

Browning BL, Huebner C, Petermann I, Gearry RB, Barclay ML, Shelling AN, Ferguson LR.

Am J Gastroenterol. 2007 Nov;102(11):2504-12. Epub 2007 Sep 10.PMID: 17850411 [PubMed - indexed for MEDLINE]Related articles

No association of the 94T/G polymorphism in the adiponectin gene with diabetic complications.

Rudofsky G Jr, Schlimme M, Schlotterer A, von Eynatten M, Reismann P, Tafel J, Grafe I, Morcos M, Nawroth P, Bierhaus A, Hamann A.

Diabetes Obes Metab. 2005 Jul;7(4):455-9.PMID: 15955133 [PubMed - indexed for MEDLINE]Related articles

Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis.

Franchimont D, Vermeire S, El Housni H, Pierik M, Van Steen K, Gustot T, Quertinmont E, Abramowicz M, Van Gossum A, Devière J, Rutgeerts P.

Gut. 2004 Jul;53(7):987-92.PMID: 15194649 [PubMed - indexed for MEDLINE]Related articlesFree article