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C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001.

Palmer JP, Fleming GA, Greenbaum CJ, Herold KC, Jansa LD, Kolb H, Lachin JM, Polonsky KS, Pozzilli P, Skyler JS, Steffes MW.

Diabetes. 2004 Jan;53(1):250-64. Erratum in: Diabetes. 2004 Jul;53(7):1934. PMID: 14693724 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell function and the development of diabetes-related complications in the diabetes control and complications trial.

Steffes MW, Sibley S, Jackson M, Thomas W.

Diabetes Care. 2003 Mar;26(3):832-6.PMID: 12610045 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of intensive therapy on residual beta-cell function in patients with type 1 diabetes in the diabetes control and complications trial. A randomized, controlled trial. The Diabetes Control and Complications Trial Research Group.

[No authors listed]

Ann Intern Med. 1998 Apr 1;128(7):517-23.PMID: 9518395 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-score: an assessment of beta-cell function after islet transplantation.

Ryan EA, Paty BW, Senior PA, Lakey JR, Bigam D, Shapiro AM.

Diabetes Care. 2005 Feb;28(2):343-7.PMID: 15677790 [PubMed - indexed for MEDLINE]Related articlesFree article

Managing type 2 diabetes: going beyond glycemic control.

Stolar MW, Hoogwerf BJ, Gorshow SM, Boyle PJ, Wales DO.

J Manag Care Pharm. 2008 Jun;14(5 Suppl B):s2-19.PMID: 18597582 [PubMed - indexed for MEDLINE]Related articlesFree article

Potential role of oral thiazolidinedione therapy in preserving beta-cell function in type 2 diabetes mellitus.

Walter H, Lübben G.

Drugs. 2005;65(1):1-13. Review.PMID: 15610048 [PubMed - indexed for MEDLINE]Related articles

Markers of beta cell function in type 1 diabetes mellitus.

Vendrame F, Zappaterreno A, Dotta F.

Minerva Med. 2004 Apr;95(2):79-84. Review.PMID: 15272242 [PubMed - indexed for MEDLINE]Related articles

Correlation between beta cell mass and glycemic control in type 1 diabetic recipients of islet cell graft.

Keymeulen B, Gillard P, Mathieu C, Movahedi B, Maleux G, Delvaux G, Ysebaert D, Roep B, Vandemeulebroucke E, Marichal M, In 't Veld P, Bogdani M, Hendrieckx C, Gorus F, Ling Z, van Rood J, Pipeleers D.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17444-9. Epub 2006 Nov 7.PMID: 17090674 [PubMed - indexed for MEDLINE]Related articlesFree article

Five-year follow-up after clinical islet transplantation.

Ryan EA, Paty BW, Senior PA, Bigam D, Alfadhli E, Kneteman NM, Lakey JR, Shapiro AM.

Diabetes. 2005 Jul;54(7):2060-9.PMID: 15983207 [PubMed - indexed for MEDLINE]Related articlesFree article

Oral antidiabetic agents: current role in type 2 diabetes mellitus.

Krentz AJ, Bailey CJ.

Drugs. 2005;65(3):385-411. Review.PMID: 15669880 [PubMed - indexed for MEDLINE]Related articles

CRP and IL-6 concentrations are associated with poor glycemic control despite preserved beta-cell function during the first year after diagnosis of type 1 diabetes.

Schölin A, Siegbahn A, Lind L, Berne C, Sundkvist G, Björk E, Karlsson FA; Diabetes Incidence Study in Sweden group.

Diabetes Metab Res Rev. 2004 May-Jun;20(3):205-10.PMID: 15133751 [PubMed - indexed for MEDLINE]Related articles

Insulin requirements and residual beta-cell function 12 months after concluding immunotherapy in type I diabetic patients treated with combined azathioprine and thymostimulin administration for one year.

Moncada E, Subirá ML, Oleaga A, Goñi F, Sánchez-Ibarrola A, Monreal M, Sevilla M, Goñi MJ, Yoldi A, Terán D, et al.

J Autoimmun. 1990 Oct;3(5):625-38.PMID: 2252531 [PubMed - indexed for MEDLINE]Related articles

[Clinical value of C-peptide determination]

Meier C, Ladewig A, Keller U, Berger W.

Praxis (Bern 1994). 1997 Aug 20;86(34):1289-95. Review. German. PMID: 9381016 [PubMed - indexed for MEDLINE]Related articles

Therapies aimed at preservation or restoration of beta cell function in type 1 diabetes.

Keymeulen B.

Verh K Acad Geneeskd Belg. 2008;70(2):85-103. Review.PMID: 18630722 [PubMed - indexed for MEDLINE]Related articles

Improved human pancreatic islet isolation for a prospective cohort study of islet transplantation vs best medical therapy in type 1 diabetes mellitus.

Warnock GL, Meloche RM, Thompson D, Shapiro RJ, Fung M, Ao Z, Ho S, He Z, Dai LJ, Young L, Blackburn L, Kozak S, Kim PT, Al-Adra D, Johnson JD, Liao YH, Elliott T, Verchere CB.

Arch Surg. 2005 Aug;140(8):735-44.PMID: 16103282 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 1 diabetes intervention trials: what have we learned? A critical review of selected intervention trials.

Greenbaum CJ.

Clin Immunol. 2002 Aug;104(2):97-104. Review.PMID: 12165270 [PubMed - indexed for MEDLINE]Related articles

beta-cell failure in diabetes and preservation by clinical treatment.

Wajchenberg BL.

Endocr Rev. 2007 Apr;28(2):187-218. Epub 2007 Mar 12. Review.PMID: 17353295 [PubMed - indexed for MEDLINE]Related articlesFree article

International trial of the Edmonton protocol for islet transplantation.

Shapiro AM, Ricordi C, Hering BJ, Auchincloss H, Lindblad R, Robertson RP, Secchi A, Brendel MD, Berney T, Brennan DC, Cagliero E, Alejandro R, Ryan EA, DiMercurio B, Morel P, Polonsky KS, Reems JA, Bretzel RG, Bertuzzi F, Froud T, Kandaswamy R, Sutherland DE, Eisenbarth G, Segal M, Preiksaitis J, Korbutt GS, Barton FB, Viviano L, Seyfert-Margolis V, Bluestone J, Lakey JR.

N Engl J Med. 2006 Sep 28;355(13):1318-30.PMID: 17005949 [PubMed - indexed for MEDLINE]Related articlesFree article

C-peptide in juvenile diabetes.

Ludvigsson J, Heding LG.

Acta Paediatr Scand Suppl. 1977;(270):53-62.PMID: 356517 [PubMed - indexed for MEDLINE]Related articles

beta-cell function in children with diabetes.

Ludvigsson J, Heding LG.

Diabetes. 1978;27 Suppl 1:230-4.PMID: 344114 [PubMed - indexed for MEDLINE]Related articles