PubMed

Inhibition of lipase activity and lipolysis in rat islets reduces insulin secretion.

Mulder H, Yang S, Winzell MS, Holm C, Ahrén B.

Diabetes. 2004 Jan;53(1):122-8.PMID: 14693706 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling.

Nolan CJ, Leahy JL, Delghingaro-Augusto V, Moibi J, Soni K, Peyot ML, Fortier M, Guay C, Lamontagne J, Barbeau A, Przybytkowski E, Joly E, Masiello P, Wang S, Mitchell GA, Prentki M.

Diabetologia. 2006 Sep;49(9):2120-30. Epub 2006 Jul 26.PMID: 16868750 [PubMed - indexed for MEDLINE]Related articles

Lipases in the pancreatic beta-cell: implications for insulin secretion.

Fex M, Mulder H.

Biochem Soc Trans. 2008 Oct;36(Pt 5):885-90. Review.PMID: 18793156 [PubMed - indexed for MEDLINE]Related articles

Glucose-stimulated insulin secretion correlates with beta-cell lipolysis.

Winzell MS, Ström K, Holm C, Ahrén B.

Nutr Metab Cardiovasc Dis. 2006 Mar;16 Suppl 1:S11-6. Epub 2006 Feb 9.PMID: 16530123 [PubMed - indexed for MEDLINE]Related articles

Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1.

Peyot ML, Nolan CJ, Soni K, Joly E, Lussier R, Corkey BE, Wang SP, Mitchell GA, Prentki M.

Diabetes. 2004 Jul;53(7):1733-42.PMID: 15220197 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion.

Peyot ML, Guay C, Latour MG, Lamontagne J, Lussier R, Pineda M, Ruderman NB, Haemmerle G, Zechner R, Joly E, Madiraju SR, Poitout V, Prentki M.

J Biol Chem. 2009 Jun 19;284(25):16848-59. Epub 2009 Apr 22.PMID: 19389712 [PubMed - indexed for MEDLINE]Related articles

Deletion of PKCepsilon selectively enhances the amplifying pathways of glucose-stimulated insulin secretion via increased lipolysis in mouse beta-cells.

Cantley J, Burchfield JG, Pearson GL, Schmitz-Peiffer C, Leitges M, Biden TJ.

Diabetes. 2009 Aug;58(8):1826-34. Epub 2009 Apr 28.PMID: 19401415 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of lipolytic activity by long-chain acyl-coenzyme A in islets and adipocytes.

Hu L, Deeney JT, Nolan CJ, Peyot ML, Ao A, Richard AM, Luc E, Faergeman NJ, Knudsen J, Guo W, Sorhede-Winzell M, Prentki M, Corkey BE.

Am J Physiol Endocrinol Metab. 2005 Dec;289(6):E1085-92. Epub 2005 Aug 9.PMID: 16091387 [PubMed - indexed for MEDLINE]Related articlesFree article

Hormone-sensitive lipase deficiency in mouse islets abolishes neutral cholesterol ester hydrolase activity but leaves lipolysis, acylglycerides, fat oxidation, and insulin secretion intact.

Fex M, Olofsson CS, Fransson U, Bacos K, Lindvall H, Sörhede-Winzell M, Rorsman P, Holm C, Mulder H.

Endocrinology. 2004 Aug;145(8):3746-53. Epub 2004 May 13.PMID: 15142983 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic beta-cell lipoprotein lipase independently regulates islet glucose metabolism and normal insulin secretion.

Pappan KL, Pan Z, Kwon G, Marshall CA, Coleman T, Goldberg IJ, McDaniel ML, Semenkovich CF.

J Biol Chem. 2005 Mar 11;280(10):9023-9. Epub 2005 Jan 6.PMID: 15637076 [PubMed - indexed for MEDLINE]Related articlesFree article

The expression of hormone-sensitive lipase in clonal beta-cells and rat islets is induced by long-term exposure to high glucose.

Winzell MS, Svensson H, Arner P, Ahrén B, Holm C.

Diabetes. 2001 Oct;50(10):2225-30.PMID: 11574402 [PubMed - indexed for MEDLINE]Related articlesFree article

Anaplerosis via pyruvate carboxylase is required for the fuel-induced rise in the ATP:ADP ratio in rat pancreatic islets.

Fransson U, Rosengren AH, Schuit FC, Renström E, Mulder H.

Diabetologia. 2006 Jul;49(7):1578-86. Epub 2006 Apr 26.PMID: 16752176 [PubMed - indexed for MEDLINE]Related articles

Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.

Herrero L, Rubí B, Sebastián D, Serra D, Asins G, Maechler P, Prentki M, Hegardt FG.

Diabetes. 2005 Feb;54(2):462-71.PMID: 15677504 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide 1 and fatty acids amplify pulsatile insulin secretion from perifused rat islets.

Cunningham BA, Richard AM, Dillon JS, Daley JT, Civelek VN, Deeney JT, Yaney GC, Corkey BE, Tornheim K.

Biochem J. 2003 Jan 1;369(Pt 1):173-8.PMID: 12356335 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose triggers protein kinase A-dependent insulin secretion in mouse pancreatic islets through activation of the K+ATP channel-dependent pathway.

Thams P, Anwar MR, Capito K.

Eur J Endocrinol. 2005 Apr;152(4):671-7.PMID: 15817925 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of beta-cell rest by a Kir6.2/SUR1-selective K(ATP)-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose.

Ritzel RA, Hansen JB, Veldhuis JD, Butler PC.

J Clin Endocrinol Metab. 2004 Feb;89(2):795-805.PMID: 14764798 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose and insulin stimulate heparin-releasable lipoprotein lipase activity in mouse islets and INS-1 cells. A potential link between insulin resistance and beta-cell dysfunction.

Cruz WS, Kwon G, Marshall CA, McDaniel ML, Semenkovich CF.

J Biol Chem. 2001 Apr 13;276(15):12162-8. Epub 2001 Jan 11.PMID: 11154699 [PubMed - indexed for MEDLINE]Related articlesFree article

cAMP-mediated signaling normalizes glucose-stimulated insulin secretion in uncoupling protein-2 overexpressing beta-cells.

McQuaid TS, Saleh MC, Joseph JW, Gyulkhandanyan A, Manning-Fox JE, MacLellan JD, Wheeler MB, Chan CB.

J Endocrinol. 2006 Sep;190(3):669-80.PMID: 17003268 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose uptake, utilization, and signaling in GLUT2-null islets.

Guillam MT, Dupraz P, Thorens B.

Diabetes. 2000 Sep;49(9):1485-91.PMID: 10969832 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of diacylglycerol lipase inhibitor RHC 80267 on pancreatic mouse islet metabolism and insulin secretion.

Capito K, Hansen SE, Hedeskov CJ, Thams P.

Diabetologia. 1989 Feb;32(2):111-7.PMID: 2656350 [PubMed - indexed for MEDLINE]Related articles