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    Results: 1 to 20 of 393

    1.

    IL-1 receptor deficiency slows progression to diabetes in the NOD mouse.

    Thomas HE, Irawaty W, Darwiche R, Brodnicki TC, Santamaria P, Allison J, Kay TW.

    Diabetes. 2004 Jan;53(1):113-21.PMID: 14693705 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.

    Chong MM, Chen Y, Darwiche R, Dudek NL, Irawaty W, Santamaria P, Allison J, Kay TW, Thomas HE.

    J Immunol. 2004 May 1;172(9):5714-21.PMID: 15100317 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12-induced IFN-gamma.

    Trembleau S, Penna G, Gregori S, Giarratana N, Adorini L.

    J Immunol. 2003 Jun 1;170(11):5491-501.PMID: 12759426 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules.

    Balasa B, Van Gunst K, Jung N, Balakrishna D, Santamaria P, Hanafusa T, Itoh N, Sarvetnick N.

    J Immunol. 2000 Sep 1;165(5):2841-9.PMID: 10946317 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus.

    Rabinovitch A.

    Diabetes Metab Rev. 1998 Jun;14(2):129-51. Review.PMID: 9679667 [PubMed - indexed for MEDLINE]Related articles

    6.

    Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice: identification of iNOS- expressing cells and relationships to cytokines expressed in the islets.

    Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Bleackley RC.

    Endocrinology. 1996 May;137(5):2093-9.PMID: 8612552 [PubMed - indexed for MEDLINE]Related articles

    7.

    IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death.

    Suk K, Kim S, Kim YH, Kim KA, Chang I, Yagita H, Shong M, Lee MS.

    J Immunol. 2001 Apr 1;166(7):4481-9.PMID: 11254704 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes.

    Amrani A, Verdaguer J, Thiessen S, Bou S, Santamaria P.

    J Clin Invest. 2000 Feb;105(4):459-68.PMID: 10683375 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells.

    Chen MC, Proost P, Gysemans C, Mathieu C, Eizirik DL.

    Diabetologia. 2001 Mar;44(3):325-32.PMID: 11317664 [PubMed - indexed for MEDLINE]Related articles

    10.

    Pancreatic IL-4 expression results in islet-reactive Th2 cells that inhibit diabetogenic lymphocytes in the nonobese diabetic mouse.

    Gallichan WS, Balasa B, Davies JD, Sarvetnick N.

    J Immunol. 1999 Aug 1;163(3):1696-703.PMID: 10415077 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Essential role for signal transducer and activator of transcription-1 in pancreatic beta-cell death and autoimmune type 1 diabetes of nonobese diabetic mice.

    Kim S, Kim HS, Chung KW, Oh SH, Yun JW, Im SH, Lee MK, Kim KW, Lee MS.

    Diabetes. 2007 Oct;56(10):2561-8. Epub 2007 Jul 9.PMID: 17620422 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha.

    Pakala SV, Chivetta M, Kelly CB, Katz JD.

    J Exp Med. 1999 Apr 5;189(7):1053-62.PMID: 10190896 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.

    Hong TP, Andersen NA, Nielsen K, Karlsen AE, Fantuzzi G, Eizirik DL, Dinarello CA, Mandrup-Poulsen T.

    Eur Cytokine Netw. 2000 Jun;11(2):193-205.PMID: 10903798 [PubMed - indexed for MEDLINE]Related articles

    14.

    Differential impact of T cell repertoire diversity in diabetes-prone or -resistant IL-10 transgenic mice.

    Balasa B, Lee J, Sarvetnick N.

    Cell Immunol. 1999 May 1;193(2):170-8.PMID: 10222059 [PubMed - indexed for MEDLINE]Related articles

    15.

    Interleukin-21 is required for the development of type 1 diabetes in NOD mice.

    Sutherland AP, Van Belle T, Wurster AL, Suto A, Michaud M, Zhang D, Grusby MJ, von Herrath M.

    Diabetes. 2009 May;58(5):1144-55. Epub 2009 Feb 10.PMID: 19208913 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Mechanisms of accelerated immune-mediated diabetes resulting from islet beta cell expression of a Fas ligand transgene.

    Silva DG, Petrovsky N, Socha L, Slattery R, Gatenby P, Charlton B.

    J Immunol. 2003 May 15;170(10):4996-5002.PMID: 12734343 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production.

    Thomas HE, Darwiche R, Corbett JA, Kay TW.

    Diabetes. 2002 Feb;51(2):311-6.PMID: 11812737 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Evidence that beta cell death in the nonobese diabetic mouse is Fas independent.

    Thomas HE, Darwiche R, Corbett JA, Kay TW.

    J Immunol. 1999 Aug 1;163(3):1562-9.PMID: 10415060 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets.

    Suarez-Pinzon W, Sorensen O, Bleackley RC, Elliott JF, Rajotte RV, Rabinovitch A.

    Diabetes. 1999 Jan;48(1):21-8.PMID: 9892218 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Th1 to Th2 cytokine shifts in nonobese diabetic mice: sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation.

    Serreze DV, Chapman HD, Post CM, Johnson EA, Suarez-Pinzon WL, Rabinovitch A.

    J Immunol. 2001 Jan 15;166(2):1352-9.PMID: 11145720 [PubMed - indexed for MEDLINE]Related articlesFree article

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