PubMed

Caspase-1 is not required for type 1 diabetes in the NOD mouse.

Schott WH, Haskell BD, Tse HM, Milton MJ, Piganelli JD, Choisy-Rossi CM, Reifsnyder PC, Chervonsky AV, Leiter EH.

Diabetes. 2004 Jan;53(1):99-104.PMID: 14693703 [PubMed - indexed for MEDLINE]Related articlesFree article

Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice.

Alleva DG, Pavlovich RP, Grant C, Kaser SB, Beller DI.

Diabetes. 2000 Jul;49(7):1106-15.PMID: 10909966 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-1 receptor deficiency slows progression to diabetes in the NOD mouse.

Thomas HE, Irawaty W, Darwiche R, Brodnicki TC, Santamaria P, Allison J, Kay TW.

Diabetes. 2004 Jan;53(1):113-21.PMID: 14693705 [PubMed - indexed for MEDLINE]Related articlesFree article

Hematopoietic stem-cell defects underlying abnormal macrophage development and maturation in NOD/Lt mice: defective regulation of cytokine receptors and protein kinase C.

Serreze DV, Gaedeke JW, Leiter EH.

Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9625-9.PMID: 8415751 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunostimulation circumvents diabetes in NOD/Lt mice.

Serreze DV, Hamaguchi K, Leiter EH.

J Autoimmun. 1989 Dec;2(6):759-76.PMID: 2533502 [PubMed - indexed for MEDLINE]Related articles

Heightened interferon-alpha/beta response causes myeloid cell dysfunction and promotes T1D pathogenesis in NOD mice.

Peng RH, Paek E, Xia CQ, Tennyson N, Clare-Salzler MJ.

Ann N Y Acad Sci. 2006 Oct;1079:99-102.PMID: 17130537 [PubMed - indexed for MEDLINE]Related articles

Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice.

Serreze DV, Post CM, Chapman HD, Johnson EA, Lu B, Rothman PB.

Diabetes. 2000 Dec;49(12):2007-11.PMID: 11118001 [PubMed - indexed for MEDLINE]Related articlesFree article

Nicotine reduces the incidence of type I diabetes in mice.

Mabley JG, Pacher P, Southan GJ, Salzman AL, Szabó C.

J Pharmacol Exp Ther. 2002 Mar;300(3):876-81.PMID: 11861793 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokines activate caspase-3 in insulinoma cells of diabetes-prone NOD mice directly and via upregulation of Fas.

Augstein P, Bahr J, Wachlin G, Heinke P, Berg S, Salzsieder E, Harrison LC.

J Autoimmun. 2004 Dec;23(4):301-9.PMID: 15571924 [PubMed - indexed for MEDLINE]Related articles

MFP14, a multifunctional emerging protein with immunomodulatory properties, prevents spontaneous and recurrent autoimmune diabetes in NOD mice.

Panerai AE, Nicoletti F, Sacedote P, Arvidsson L, Conget I, Gomis R, Bartorelli A, Sandler S.

Diabetologia. 2001 Jul;44(7):839-47.PMID: 11508268 [PubMed - indexed for MEDLINE]Related articles

Dysregulated Toll-like receptor expression and signaling in bone marrow-derived macrophages at the onset of diabetes in the non-obese diabetic mouse.

Mohammad MK, Morran M, Slotterbeck B, Leaman DW, Sun Y, Grafenstein H, Hong SC, McInerney MF.

Int Immunol. 2006 Jul;18(7):1101-13. Epub 2006 May 25. Erratum in: Int Immunol. 2007 Apr;19(4):581. PMID: 16728431 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage migration inhibitory factor (MIF) is necessary for progression of autoimmune diabetes mellitus.

Stosic-Grujicic S, Stojanovic I, Maksimovic-Ivanic D, Momcilovic M, Popadic D, Harhaji L, Miljkovic D, Metz C, Mangano K, Papaccio G, Al-Abed Y, Nicoletti F.

J Cell Physiol. 2008 Jun;215(3):665-75.PMID: 18064633 [PubMed - indexed for MEDLINE]Related articles

Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type 1 diabetes by activated CD1d-restricted invariant natural killer T-cells.

Mi QS, Ly D, Zucker P, McGarry M, Delovitch TL.

Diabetes. 2004 May;53(5):1303-10.PMID: 15111500 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential role for signal transducer and activator of transcription-1 in pancreatic beta-cell death and autoimmune type 1 diabetes of nonobese diabetic mice.

Kim S, Kim HS, Chung KW, Oh SH, Yun JW, Im SH, Lee MK, Kim KW, Lee MS.

Diabetes. 2007 Oct;56(10):2561-8. Epub 2007 Jul 9.PMID: 17620422 [PubMed - indexed for MEDLINE]Related articlesFree article

Failure of exogenously administered interferon-gamma or blockage of endogenous interleukin-4 with specific inhibitors to augment the incidence of autoimmune diabetes in male NOD mice.

Xiang M, Zaccone P, Di Marco R, Harris R, Magro G, Di Mauro M, Meroni PL, Garotta G, Nicoletti F.

Autoimmunity. 1999;30(2):71-80.PMID: 10435719 [PubMed - indexed for MEDLINE]Related articles

The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.

Mabley JG, Pacher P, Murthy KG, Williams W, Southan GJ, Salzman AL, Szabo C.

J Endocrinol. 2008 Sep;198(3):581-9. Epub 2008 Jun 18.PMID: 18562629 [PubMed - indexed for MEDLINE]Related articlesFree article

Unaltered diabetes presentation in NOD mice lacking the vitamin D receptor.

Gysemans C, van Etten E, Overbergh L, Giulietti A, Eelen G, Waer M, Verstuyf A, Bouillon R, Mathieu C.

Diabetes. 2008 Jan;57(1):269-75. Epub 2007 Oct 24.PMID: 17959935 [PubMed - indexed for MEDLINE]Related articlesFree article

Early prophylaxis with recombinant human interleukin-11 prevents spontaneous diabetes in NOD mice.

Nicoletti F, Zaccone P, Conget I, Gomis R, Möller C, Meroni PL, Bendtzen K, Trepicchio W, Sandler S.

Diabetes. 1999 Dec;48(12):2333-9.PMID: 10580421 [PubMed - indexed for MEDLINE]Related articlesFree article

A potent immunomodulatory compound, (S,R)-3-Phenyl-4,5-dihydro-5-isoxazole acetic acid, prevents spontaneous and accelerated forms of autoimmune diabetes in NOD mice and inhibits the immunoinflammatory diabetes induced by multiple low doses of streptozotocin in CBA/H mice.

Stosic-Grujicic S, Cvetkovic I, Mangano K, Fresta M, Maksimovic-Ivanic D, Harhaji L, Popadic D, Momcilovic M, Miljkovic D, Kim J, Al-Abed Y, Nicoletti F.

J Pharmacol Exp Ther. 2007 Mar;320(3):1038-49. Epub 2006 Dec 5. Erratum in: J Pharmacol Exp Ther. 2007 Apr;321(1):420. Abed, Yousef Al [corrected to Al-Abed, Yousef]. PMID: 17148780 [PubMed - indexed for MEDLINE]Related articlesFree article

Cuttine edge: diabetes-associated quantitative trait locus, Idd4, is responsible for the IL-12p40 overexpression defect in nonobese diabetic (NOD) mice.

Simpson PB, Mistry MS, Maki RA, Yang W, Schwarz DA, Johnson EB, Lio FM, Alleva DG.

J Immunol. 2003 Oct 1;171(7):3333-7.PMID: 14500624 [PubMed - indexed for MEDLINE]Related articlesFree article