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    Results: 1 to 20 of 184

    2.

    New insights concerning the glucose-dependent insulin secretagogue action of glucagon-like peptide-1 in pancreatic beta-cells.

    Holz GG.

    Horm Metab Res. 2004 Nov-Dec;36(11-12):787-94. Erratum in: Horm Metab Res. 2005 Feb;37(2):126. Holz, G [corrected to Holz, GG]. PMID: 15655710 [PubMed - indexed for MEDLINE]Related articles

    3.

    Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.

    Kang G, Joseph JW, Chepurny OG, Monaco M, Wheeler MB, Bos JL, Schwede F, Genieser HG, Holz GG.

    J Biol Chem. 2003 Mar 7;278(10):8279-85. Epub 2002 Dec 20.PMID: 12496249 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic beta cells.

    Kang G, Chepurny OG, Rindler MJ, Collis L, Chepurny Z, Li WH, Harbeck M, Roe MW, Holz GG.

    J Physiol. 2005 Jul 1;566(Pt 1):173-88. Epub 2005 Apr 28.PMID: 15860526 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Cell physiology of cAMP sensor Epac.

    Holz GG, Kang G, Harbeck M, Roe MW, Chepurny OG.

    J Physiol. 2006 Nov 15;577(Pt 1):5-15. Epub 2006 Sep 14. Review.PMID: 16973695 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells.

    Kang G, Chepurny OG, Malester B, Rindler MJ, Rehmann H, Bos JL, Schwede F, Coetzee WA, Holz GG.

    J Physiol. 2006 Jun 15;573(Pt 3):595-609. Epub 2006 Apr 13.PMID: 16613879 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.

    Holz GG, Chepurny OG, Schwede F.

    Cell Signal. 2008 Jan;20(1):10-20. Epub 2007 Jul 25. Review.PMID: 17716863 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Epac is involved in cAMP-stimulated proglucagon expression and hormone production but not hormone secretion in pancreatic alpha- and intestinal L-cell lines.

    Islam D, Zhang N, Wang P, Li H, Brubaker PL, Gaisano HY, Wang Q, Jin T.

    Am J Physiol Endocrinol Metab. 2009 Jan;296(1):E174-81. Epub 2008 Oct 14.PMID: 18854429 [PubMed - indexed for MEDLINE]Related articles

    11.

    Generation of nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose by glucagon-like peptide-1 evokes Ca2+ signal that is essential for insulin secretion in mouse pancreatic islets.

    Kim BJ, Park KH, Yim CY, Takasawa S, Okamoto H, Im MJ, Kim UH.

    Diabetes. 2008 Apr;57(4):868-78. Epub 2008 Jan 9.PMID: 18184929 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells.

    Eliasson L, Ma X, Renström E, Barg S, Berggren PO, Galvanovskis J, Gromada J, Jing X, Lundquist I, Salehi A, Sewing S, Rorsman P.

    J Gen Physiol. 2003 Mar;121(3):181-97.PMID: 12601083 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor.

    Rangarajan S, Enserink JM, Kuiperij HB, de Rooij J, Price LS, Schwede F, Bos JL.

    J Cell Biol. 2003 Feb 17;160(4):487-93. Epub 2003 Feb 10.PMID: 12578910 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Ca(2+)-induced Ca(2+) release via inositol 1,4,5-trisphosphate receptors is amplified by protein kinase A and triggers exocytosis in pancreatic beta-cells.

    Dyachok O, Gylfe E.

    J Biol Chem. 2004 Oct 29;279(44):45455-61. Epub 2004 Aug 16.PMID: 15316011 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis.

    Shibasaki T, Sunaga Y, Fujimoto K, Kashima Y, Seino S.

    J Biol Chem. 2004 Feb 27;279(9):7956-61. Epub 2003 Dec 3.PMID: 14660679 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells.

    Kwan EP, Xie L, Sheu L, Ohtsuka T, Gaisano HY.

    Diabetes. 2007 Oct;56(10):2579-88. Epub 2007 Jul 16.PMID: 17639022 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Expression of cAMP-regulated guanine nucleotide exchange factors in pancreatic beta-cells.

    Leech CA, Holz GG, Chepurny O, Habener JF.

    Biochem Biophys Res Commun. 2000 Nov 11;278(1):44-7.PMID: 11071853 [PubMed - indexed for MEDLINE]Related articles

    18.

    Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors.

    Gromada J, Ding WG, Barg S, Renström E, Rorsman P.

    Pflugers Arch. 1997 Sep;434(5):515-24.PMID: 9242714 [PubMed - indexed for MEDLINE]Related articles

    19.

    Glucagon stimulates exocytosis in mouse and rat pancreatic alpha-cells by binding to glucagon receptors.

    Ma X, Zhang Y, Gromada J, Sewing S, Berggren PO, Buschard K, Salehi A, Vikman J, Rorsman P, Eliasson L.

    Mol Endocrinol. 2005 Jan;19(1):198-212. Epub 2004 Sep 30.PMID: 15459251 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    cAMP increases Ca2+-dependent exocytosis through both PKA and Epac2 in mouse melanotrophs from pituitary tissue slices.

    Sedej S, Rose T, Rupnik M.

    J Physiol. 2005 Sep 15;567(Pt 3):799-813. Epub 2005 Jun 30.PMID: 15994184 [PubMed - indexed for MEDLINE]Related articlesFree article

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