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    Results: 1 to 20 of 630

    1.

    Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels.

    Richter S, Shih DQ, Pearson ER, Wolfrum C, Fajans SS, Hattersley AT, Stoffel M.

    Diabetes. 2003 Dec;52(12):2989-95.PMID: 14633861 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Genotype/phenotype relationships in HNF-4alpha/MODY1: haploinsufficiency is associated with reduced apolipoprotein (AII), apolipoprotein (CIII), lipoprotein(a), and triglyceride levels.

    Shih DQ, Dansky HM, Fleisher M, Assmann G, Fajans SS, Stoffel M.

    Diabetes. 2000 May;49(5):832-7.PMID: 10905494 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Hepatocyte nuclear factor-1alpha modulates pancreatic beta-cell growth by regulating the expression of insulin-like growth factor-1 in INS-1 cells.

    Yang Q, Yamagata K, Fukui K, Cao Y, Nammo T, Iwahashi H, Wang H, Matsumura I, Hanafusa T, Bucala R, Wollheim CB, Miyagawa J, Matsuzawa Y.

    Diabetes. 2002 Jun;51(6):1785-92.PMID: 12031966 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Liver and kidney function in Japanese patients with maturity-onset diabetes of the young.

    Iwasaki N, Ogata M, Tomonaga O, Kuroki H, Kasahara T, Yano N, Iwamoto Y.

    Diabetes Care. 1998 Dec;21(12):2144-8.PMID: 9839108 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Decreased glibenclamide uptake in hepatocytes of hepatocyte nuclear factor-1alpha-deficient mice: a mechanism for hypersensitivity to sulfonylurea therapy in patients with maturity-onset diabetes of the young, type 3 (MODY3).

    Boileau P, Wolfrum C, Shih DQ, Yang TA, Wolkoff AW, Stoffel M.

    Diabetes. 2002 Dec;51 Suppl 3:S343-8.PMID: 12475773 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism.

    Shih DQ, Screenan S, Munoz KN, Philipson L, Pontoglio M, Yaniv M, Polonsky KS, Stoffel M.

    Diabetes. 2001 Nov;50(11):2472-80.PMID: 11679424 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Mutation P291fsinsC in the transcription factor hepatocyte nuclear factor-1alpha is dominant negative.

    Yamagata K, Yang Q, Yamamoto K, Iwahashi H, Miyagawa J, Okita K, Yoshiuchi I, Miyazaki J, Noguchi T, Nakajima H, Namba M, Hanafusa T, Matsuzawa Y.

    Diabetes. 1998 Aug;47(8):1231-5.PMID: 9703322 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

    Yamagata K, Furuta H, Oda N, Kaisaki PJ, Menzel S, Cox NJ, Fajans SS, Signorini S, Stoffel M, Bell GI.

    Nature. 1996 Dec 5;384(6608):458-60.PMID: 8945471 [PubMed - indexed for MEDLINE]Related articles

    9.

    Human insulin gene is a target gene of hepatocyte nuclear factor-1alpha (HNF-1alpha) and HNF-1beta.

    Okita K, Yang Q, Yamagata K, Hangenfeldt KA, Miyagawa J, Kajimoto Y, Nakajima H, Namba M, Wollheim CB, Hanafusa T, Matsuzawa Y.

    Biochem Biophys Res Commun. 1999 Sep 24;263(2):566-9.PMID: 10491332 [PubMed - indexed for MEDLINE]Related articles

    10.

    Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function.

    Hansen SK, Párrizas M, Jensen ML, Pruhova S, Ek J, Boj SF, Johansen A, Maestro MA, Rivera F, Eiberg H, Andel M, Lebl J, Pedersen O, Ferrer J, Hansen T.

    J Clin Invest. 2002 Sep;110(6):827-33.PMID: 12235114 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Liver-specific reactivation of the inactivated Hnf-1alpha gene: elimination of liver dysfunction to establish a mouse MODY3 model.

    Lee YH, Magnuson MA, Muppala V, Chen SS.

    Mol Cell Biol. 2003 Feb;23(3):923-32.PMID: 12529398 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas.

    Nammo T, Yamagata K, Tanaka T, Kodama T, Sladek FM, Fukui K, Katsube F, Sato Y, Miyagawa J, Shimomura I.

    Gene Expr Patterns. 2008 Jan;8(2):96-106. Epub 2007 Oct 9.PMID: 17996499 [PubMed - indexed for MEDLINE]Related articles

    13.

    Variants in the hepatocyte nuclear factor-1alpha and -4alpha genes in Finnish and Chinese subjects with late-onset type 2 diabetes.

    Rissanen J, Wang H, Miettinen R, Kärkkäinen P, Kekäläinen P, Mykkänen L, Kuusisto J, Karhapää P, Niskanen L, Uusitupa M, Laakso M.

    Diabetes Care. 2000 Oct;23(10):1533-8.PMID: 11023148 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta.

    Shih DQ, Heimesaat M, Kuwajima S, Stein R, Wright CV, Stoffel M.

    Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3818-23.PMID: 11904435 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young (MODY3).

    Vaxillaire M, Rouard M, Yamagata K, Oda N, Kaisaki PJ, Boriraj VV, Chevre JC, Boccio V, Cox RD, Lathrop GM, Dussoix P, Philippe J, Timsit J, Charpentier G, Velho G, Bell GI, Froguel P.

    Hum Mol Genet. 1997 Apr;6(4):583-6.PMID: 9097962 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    A novel Phe75fsdelT mutation in the hepatocyte nuclear factor-4alpha gene in a Danish pedigree with maturity-onset diabetes of the young.

    Møller AM, Dalgaard LT, Ambye L, Hansen L, Schmitz O, Hansen T, Pedersen O.

    J Clin Endocrinol Metab. 1999 Jan;84(1):367-9.PMID: 9920109 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Counterregulatory responses to hypoglycemia in patients with maturity-onset diabetes of the young caused by HNF-1alpha gene mutations (MODY3).

    Guenat E, Seematter G, Philippe J, Temler E, Jéquier E, Tappy L.

    Eur J Endocrinol. 2001 Jan;144(1):45-9.PMID: 11174836 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Hepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 gene.

    Lindner T, Gragnoli C, Furuta H, Cockburn BN, Petzold C, Rietzsch H, Weiss U, Schulze J, Bell GI.

    J Clin Invest. 1997 Sep 15;100(6):1400-5.PMID: 9294105 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.

    Pontoglio M, Sreenan S, Roe M, Pugh W, Ostrega D, Doyen A, Pick AJ, Baldwin A, Velho G, Froguel P, Levisetti M, Bonner-Weir S, Bell GI, Yaniv M, Polonsky KS.

    J Clin Invest. 1998 May 15;101(10):2215-22.PMID: 9593777 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Identification and functional analysis of mutations in the hepatocyte nuclear factor-1alpha gene in anti-islet autoantibody-negative Japanese patients with type 1 diabetes.

    Kawasaki E, Sera Y, Yamakawa K, Abe T, Ozaki M, Uotani S, Ohtsu N, Takino H, Yamasaki H, Yamaguchi Y, Matsuura N, Eguchi K.

    J Clin Endocrinol Metab. 2000 Jan;85(1):331-5.PMID: 10634407 [PubMed - indexed for MEDLINE]Related articlesFree article

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