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Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects.
Tripathy D, Mohanty P, Dhindsa S, Syed T, Ghanim H, Aljada A, Dandona P.
Diabetes. 2003 Dec;52(12):2882-7.PMID: 14633847 [PubMed - indexed for MEDLINE]Related articlesFree article
Differential effects of glucose and alcohol on reactive oxygen species generation and intranuclear nuclear factor-kappaB in mononuclear cells.
Dhindsa S, Tripathy D, Mohanty P, Ghanim H, Syed T, Aljada A, Dandona P.
Metabolism. 2004 Mar;53(3):330-4.PMID: 15015145 [PubMed - indexed for MEDLINE]Related articles
Prolonged reactive oxygen species generation and nuclear factor-kappaB activation after a high-fat, high-carbohydrate meal in the obese.
Patel C, Ghanim H, Ravishankar S, Sia CL, Viswanathan P, Mohanty P, Dandona P.
J Clin Endocrinol Metab. 2007 Nov;92(11):4476-9. Epub 2007 Sep 4.PMID: 17785362 [PubMed - indexed for MEDLINE]Related articlesFree article
Circulating mononuclear cells in the obese are in a proinflammatory state.
Ghanim H, Aljada A, Hofmeyer D, Syed T, Mohanty P, Dandona P.
Circulation. 2004 Sep 21;110(12):1564-71. Epub 2004 Sep 13.PMID: 15364812 [PubMed - indexed for MEDLINE]Related articlesFree article
Angiotensin II receptor blocker valsartan suppresses reactive oxygen species generation in leukocytes, nuclear factor-kappa B, in mononuclear cells of normal subjects: evidence of an antiinflammatory action.
Dandona P, Kumar V, Aljada A, Ghanim H, Syed T, Hofmayer D, Mohanty P, Tripathy D, Garg R.
J Clin Endocrinol Metab. 2003 Sep;88(9):4496-501.PMID: 12970329 [PubMed - indexed for MEDLINE]Related articlesFree article
Troglitazone reduces reactive oxygen species generation by leukocytes and lipid peroxidation and improves flow-mediated vasodilatation in obese subjects.
Garg R, Kumbkarni Y, Aljada A, Mohanty P, Ghanim H, Hamouda W, Dandona P.
Hypertension. 2000 Sep;36(3):430-5.PMID: 10988277 [PubMed - indexed for MEDLINE]Related articlesFree article
The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation.
Dandona P, Mohanty P, Ghanim H, Aljada A, Browne R, Hamouda W, Prabhala A, Afzal A, Garg R.
J Clin Endocrinol Metab. 2001 Jan;86(1):355-62.PMID: 11232024 [PubMed - indexed for MEDLINE]Related articlesFree article
Increased IkappaB expression and diminished nuclear NF-kappaB in human mononuclear cells following hydrocortisone injection.
Aljada A, Ghanim H, Assian E, Mohanty P, Hamouda W, Garg R, Dandona P.
J Clin Endocrinol Metab. 1999 Sep;84(9):3386-9.PMID: 10487715 [PubMed - indexed for MEDLINE]Related articlesFree article
Both lipid and protein intakes stimulate increased generation of reactive oxygen species by polymorphonuclear leukocytes and mononuclear cells.
Mohanty P, Ghanim H, Hamouda W, Aljada A, Garg R, Dandona P.
Am J Clin Nutr. 2002 Apr;75(4):767-72.PMID: 11916766 [PubMed - indexed for MEDLINE]Related articlesFree article
Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action?
Aljada A, Garg R, Ghanim H, Mohanty P, Hamouda W, Assian E, Dandona P.
J Clin Endocrinol Metab. 2001 Jul;86(7):3250-6.PMID: 11443197 [PubMed - indexed for MEDLINE]Related articlesFree article
Increase in intranuclear nuclear factor kappaB and decrease in inhibitor kappaB in mononuclear cells after a mixed meal: evidence for a proinflammatory effect.
Aljada A, Mohanty P, Ghanim H, Abdo T, Tripathy D, Chaudhuri A, Dandona P.
Am J Clin Nutr. 2004 Apr;79(4):682-90.PMID: 15051615 [PubMed - indexed for MEDLINE]Related articlesFree article
Direct evidence of endothelial oxidative stress with aging in humans: relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-kappaB.
Donato AJ, Eskurza I, Silver AE, Levy AS, Pierce GL, Gates PE, Seals DR.
Circ Res. 2007 Jun 8;100(11):1659-66. Epub 2007 May 3.PMID: 17478731 [PubMed - indexed for MEDLINE]Related articlesFree article
Rosiglitazone prevents free fatty acid-induced vascular endothelial dysfunction.
Mittermayer F, Schaller G, Pleiner J, Krzyzanowska K, Kapiotis S, Roden M, Wolzt M.
J Clin Endocrinol Metab. 2007 Jul;92(7):2574-80. Epub 2007 May 1.PMID: 17473072 [PubMed - indexed for MEDLINE]Related articlesFree article
Persistent activation of nuclear factor kappa-B signaling pathway in patients with unstable angina and elevated levels of C-reactive protein evidence for a direct proinflammatory effect of azide and lipopolysaccharide-free C-reactive protein on human monocytes via nuclear factor kappa-B activation.
Liuzzo G, Santamaria M, Biasucci LM, Narducci M, Colafrancesco V, Porto A, Brugaletta S, Pinnelli M, Rizzello V, Maseri A, Crea F.
J Am Coll Cardiol. 2007 Jan 16;49(2):185-94. Epub 2006 Dec 29.PMID: 17222729 [PubMed - indexed for MEDLINE]Related articles
Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect?
Dandona P, Aljada A, Mohanty P, Ghanim H, Hamouda W, Assian E, Ahmad S.
J Clin Endocrinol Metab. 2001 Jul;86(7):3257-65.PMID: 11443198 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucose ingestion induces an increase in intranuclear nuclear factor kappaB, a fall in cellular inhibitor kappaB, and an increase in tumor necrosis factor alpha messenger RNA by mononuclear cells in healthy human subjects.
Aljada A, Friedman J, Ghanim H, Mohanty P, Hofmeyer D, Chaudhuri A, Dandona P.
Metabolism. 2006 Sep;55(9):1177-85.PMID: 16919536 [PubMed - indexed for MEDLINE]Related articles
Role of inflammatory mediators in the suppression of insulin receptor phosphorylation in circulating mononuclear cells of obese subjects.
Ghanim H, Aljada A, Daoud N, Deopurkar R, Chaudhuri A, Dandona P.
Diabetologia. 2007 Feb;50(2):278-85. Epub 2006 Dec 16.PMID: 17180352 [PubMed - indexed for MEDLINE]Related articles
Dose-response effect of elevated plasma free fatty acid on insulin signaling.
Belfort R, Mandarino L, Kashyap S, Wirfel K, Pratipanawatr T, Berria R, Defronzo RA, Cusi K.
Diabetes. 2005 Jun;54(6):1640-8.PMID: 15919784 [PubMed - indexed for MEDLINE]Related articlesFree article
Homocysteine induces VCAM-1 gene expression through NF-kappaB and NAD(P)H oxidase activation: protective role of Mediterranean diet polyphenolic antioxidants.
Carluccio MA, Ancora MA, Massaro M, Carluccio M, Scoditti E, Distante A, Storelli C, De Caterina R.
Am J Physiol Heart Circ Physiol. 2007 Oct;293(4):H2344-54. Epub 2007 Jun 22.PMID: 17586618 [PubMed - indexed for MEDLINE]Related articlesFree article
Acute haemodynamic effects of lipolysis-induced increase of free fatty acids in healthy men.
Kearney MT, Chowienczyk PJ, Brett SE, Sutcliffe A, Ritter JM, Shah AM.
Clin Sci (Lond). 2002 May;102(5):495-500.PMID: 11980566 [PubMed - indexed for MEDLINE]Related articles
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