PubMed

Cytoplasmic p21WAF1/CIP1 expression is correlated with HER-2/ neu in breast cancer and is an independent predictor of prognosis.

Winters ZE, Leek RD, Bradburn MJ, Norbury CJ, Harris AL.

Breast Cancer Res. 2003;5(6):R242-9. Epub 2003 Oct 3.PMID: 14580260 [PubMed - indexed for MEDLINE]Related articlesFree article

p14ARF expression in invasive breast cancers and ductal carcinoma in situ--relationships to p53 and Hdm2.

Vestey SB, Sen C, Calder CJ, Perks CM, Pignatelli M, Winters ZE.

Breast Cancer Res. 2004;6(5):R571-85. Epub 2004 Jul 29.PMID: 15318938 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation/cytoplasmic localization of p21Cip1/WAF1 is associated with HER2/neu overexpression and provides a novel combination predictor for poor prognosis in breast cancer patients.

Xia W, Chen JS, Zhou X, Sun PR, Lee DF, Liao Y, Zhou BP, Hung MC.

Clin Cancer Res. 2004 Jun 1;10(11):3815-24.PMID: 15173090 [PubMed - indexed for MEDLINE]Related articlesFree article

Prognostic significance of HER-2/neu oncoprotein expression in node-positive breast cancer. The influence of the pattern of immunostaining and adjuvant therapy.

Têtu B, Brisson J.

Cancer. 1994 May 1;73(9):2359-65.PMID: 7909490 [PubMed - indexed for MEDLINE]Related articles

Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.

Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.

Int J Oncol. 2004 Mar;24(3):591-608.PMID: 14767544 [PubMed - indexed for MEDLINE]Related articles

p21(waf) correlates with DNA replication but not with prognosis in invasive breast cancer.

Göhring UJ, Bersch A, Becker M, Neuhaus W, Schöndorf T.

J Clin Pathol. 2001 Nov;54(11):866-70.PMID: 11684722 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression patterns of cyclins D1, E and cyclin-dependent kinase inhibitors p21waf1/cip1, p27kip1 in colorectal carcinoma: correlation with other cell cycle regulators (pRb, p53 and Ki-67 and PCNA) and clinicopathological features.

Ioachim E.

Int J Clin Pract. 2008 Nov;62(11):1736-43.PMID: 19143860 [PubMed - indexed for MEDLINE]Related articles

Activation (tyrosine phosphorylation) of ErbB-2 (HER-2/neu): a study of incidence and correlation with outcome in breast cancer.

Thor AD, Liu S, Edgerton S, Moore D 2nd, Kasowitz KM, Benz CC, Stern DF, DiGiovanna MP.

J Clin Oncol. 2000 Sep 15;18(18):3230-9.PMID: 10986055 [PubMed - indexed for MEDLINE]Related articles

Subcellular localisation of cyclin B, Cdc2 and p21(WAF1/CIP1) in breast cancer. association with prognosis.

Winters ZE, Hunt NC, Bradburn MJ, Royds JA, Turley H, Harris AL, Norbury CJ.

Eur J Cancer. 2001 Dec;37(18):2405-12.PMID: 11720835 [PubMed - indexed for MEDLINE]Related articles

p21(Waf1/Cip1) and p53 protein expression in breast cancer.

Wakasugi E, Kobayashi T, Tamaki Y, Ito Y, Miyashiro I, Komoike Y, Takeda T, Shin E, Takatsuka Y, Kikkawa N, Monden T, Monden M.

Am J Clin Pathol. 1997 Jun;107(6):684-91.PMID: 9169666 [PubMed - indexed for MEDLINE]Related articles

Activated Akt expression in breast cancer: correlation with p53, Hdm2 and patient outcome.

Vestey SB, Sen C, Calder CJ, Perks CM, Pignatelli M, Winters ZE.

Eur J Cancer. 2005 May;41(7):1017-25.PMID: 15862750 [PubMed - indexed for MEDLINE]Related articles

Prognostic value of p21(WAF1) and p53 expression in breast carcinoma: an immunohistochemical study in 261 patients with long-term follow-up.

Caffo O, Doglioni C, Veronese S, Bonzanini M, Marchetti A, Buttitta F, Fina P, Leek R, Morelli L, Palma PD, Harris AL, Barbareschi M.

Clin Cancer Res. 1996 Sep;2(9):1591-9.PMID: 9816338 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of cyclooxygenase-2 in breast carcinogenesis and its relation to HER-2/neu and p53 protein expression in invasive ductal carcinoma.

Cho MH, Yoon JH, Jaegal YJ, Choi YD, Lee JS, Lee JH, Nam JH, Choi C, Lee MC, Park CS, Woo Juhng S, Min KW.

Breast. 2006 Jun;15(3):390-8. Epub 2005 Sep 19.PMID: 16169726 [PubMed - indexed for MEDLINE]Related articles

Expression of the cell cycle regulatory proteins p34cdc2, p21waf1, and p53 in node negative invasive ductal breast carcinoma.

Kourea HP, Koutras AK, Scopa CD, Marangos MN, Tzoracoeleftherakis E, Koukouras D, Kalofonos HP.

Mol Pathol. 2003 Dec;56(6):328-35.PMID: 14645695 [PubMed - indexed for MEDLINE]Related articlesFree article

Coexistence of HER2 over-expression and p53 protein accumulation is a strong prognostic molecular marker in breast cancer.

Yamashita H, Nishio M, Toyama T, Sugiura H, Zhang Z, Kobayashi S, Iwase H.

Breast Cancer Res. 2004;6(1):R24-30. Epub 2003 Nov 7.PMID: 14680497 [PubMed - indexed for MEDLINE]Related articlesFree article

ErbB2 overexpression in human breast carcinoma is correlated with p21Cip1 up-regulation and tyrosine-15 hyperphosphorylation of p34Cdc2: poor responsiveness to chemotherapy with cyclophoshamide methotrexate, and 5-fluorouracil is associated with Erb2 overexpression and with p21Cip1 overexpression.

Yang W, Klos KS, Zhou X, Yao J, Yang Y, Smith TL, Shi D, Yu D.

Cancer. 2003 Sep 15;98(6):1123-30.PMID: 12973835 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased cell size and Akt activation in HER-2/neu-overexpressing invasive ductal carcinoma of the breast.

Sastre-Garau X, Genin P, Rousseau A, Al Ghuzlan A, Nicolas A, Fréneaux P, Rosty C, Sigal-Zafrani B, Couturier J, Thiery JP, Magdelénat H, Vincent-Salomon A.

Histopathology. 2004 Aug;45(2):142-7.PMID: 15279632 [PubMed - indexed for MEDLINE]Related articles

[Correlations of HER-2, PCNA, Bcl-2, and Bax expression to prognosis of breast cancer]

Yang L, Zhu X, Ran L.

Ai Zheng. 2007 Jul;26(7):756-61. Chinese. PMID: 17626754 [PubMed - indexed for MEDLINE]Related articlesFree article

The efficacy of trastuzumab in Her-2/neu-overexpressing metastatic breast cancer is independent of p53 status.

Köstler WJ, Brodowicz T, Hudelist G, Rudas M, Horvat R, Steger GG, Singer CF, Attems J, Rabitsch W, Fakhrai N, Elandt K, Wiltschke C, Hejna M, Zielinski CC.

J Cancer Res Clin Oncol. 2005 Jul;131(7):420-8. Epub 2005 Apr 29.PMID: 15864644 [PubMed - indexed for MEDLINE]Related articles

Her-2/neu-triggered intracellular tyrosine kinase activation: in vivo relevance of ligand-independent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment.

Hudelist G, Köstler WJ, Attems J, Czerwenka K, Müller R, Manavi M, Steger GG, Kubista E, Zielinski CC, Singer CF.

Br J Cancer. 2003 Sep 15;89(6):983-91.PMID: 12966413 [PubMed - indexed for MEDLINE]Related articlesFree article