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Leptin and wound inflammation in diabetic ob/ob mice: differential regulation of neutrophil and macrophage influx and a potential role for the scab as a sink for inflammatory cells and mediators.
Goren I, Kämpfer H, Podda M, Pfeilschifter J, Frank S.
Diabetes. 2003 Nov;52(11):2821-32.PMID: 14578302 [PubMed - indexed for MEDLINE]Related articlesFree article
Systemically and topically supplemented leptin fails to reconstitute a normal angiogenic response during skin repair in diabetic ob/ob mice.
Stallmeyer B, Pfeilschifter J, Frank S.
Diabetologia. 2001 Apr;44(4):471-9.PMID: 11357478 [PubMed - indexed for MEDLINE]Related articles
Wound inflammation in diabetic ob/ob mice: functional coupling of prostaglandin biosynthesis to cyclooxygenase-1 activity in diabetes-impaired wound healing.
Kämpfer H, Schmidt R, Geisslinger G, Pfeilschifter J, Frank S.
Diabetes. 2005 May;54(5):1543-51.PMID: 15855344 [PubMed - indexed for MEDLINE]Related articlesFree article
Oncostatin M expression is functionally connected to neutrophils in the early inflammatory phase of skin repair: implications for normal and diabetes-impaired wounds.
Goren I, Kämpfer H, Müller E, Schiefelbein D, Pfeilschifter J, Frank S.
J Invest Dermatol. 2006 Mar;126(3):628-37.PMID: 16410783 [PubMed - indexed for MEDLINE]Related articlesFree article
Systemically and topically administered leptin both accelerate wound healing in diabetic ob/ob mice.
Ring BD, Scully S, Davis CR, Baker MB, Cullen MJ, Pelleymounter MA, Danilenko DM.
Endocrinology. 2000 Jan;141(1):446-9.PMID: 10614668 [PubMed - indexed for MEDLINE]Related articlesFree article
Severely impaired insulin signaling in chronic wounds of diabetic ob/ob mice: a potential role of tumor necrosis factor-alpha.
Goren I, Müller E, Pfeilschifter J, Frank S.
Am J Pathol. 2006 Mar;168(3):765-77.PMID: 16507892 [PubMed - indexed for MEDLINE]Related articlesFree article
Changes in glycemia by leptin administration or high- fat feeding in rodent models of obesity/type 2 diabetes suggest a link between resistin expression and control of glucose homeostasis.
Asensio C, Cettour-Rose P, Theander-Carrillo C, Rohner-Jeanrenaud F, Muzzin P.
Endocrinology. 2004 May;145(5):2206-13. Epub 2004 Feb 12.PMID: 14962997 [PubMed - indexed for MEDLINE]Related articlesFree article
Systemic anti-TNFalpha treatment restores diabetes-impaired skin repair in ob/ob mice by inactivation of macrophages.
Goren I, Müller E, Schiefelbein D, Christen U, Pfeilschifter J, Mühl H, Frank S.
J Invest Dermatol. 2007 Sep;127(9):2259-67. Epub 2007 Apr 26.PMID: 17460730 [PubMed - indexed for MEDLINE]Related articlesFree article
Leptin enhances wound re-epithelialization and constitutes a direct function of leptin in skin repair.
Frank S, Stallmeyer B, Kämpfer H, Kolb N, Pfeilschifter J.
J Clin Invest. 2000 Aug;106(4):501-9.PMID: 10953025 [PubMed - indexed for MEDLINE]Related articlesFree article
Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: prolonged persistence of neutrophils and macrophages during the late phase of repair.
Wetzler C, Kämpfer H, Stallmeyer B, Pfeilschifter J, Frank S.
J Invest Dermatol. 2000 Aug;115(2):245-53.PMID: 10951242 [PubMed - indexed for MEDLINE]Related articlesFree article
Expression and activity of arginase isoenzymes during normal and diabetes-impaired skin repair.
Kämpfer H, Pfeilschifter J, Frank S.
J Invest Dermatol. 2003 Dec;121(6):1544-51.PMID: 14675208 [PubMed - indexed for MEDLINE]Related articlesFree article
Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing.
Maruyama K, Asai J, Ii M, Thorne T, Losordo DW, D'Amore PA.
Am J Pathol. 2007 Apr;170(4):1178-91.PMID: 17392158 [PubMed - indexed for MEDLINE]Related articlesFree article
Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis and by mobilizing and recruiting bone marrow-derived cells.
Galiano RD, Tepper OM, Pelo CR, Bhatt KA, Callaghan M, Bastidas N, Bunting S, Steinmetz HG, Gurtner GC.
Am J Pathol. 2004 Jun;164(6):1935-47.PMID: 15161630 [PubMed - indexed for MEDLINE]Related articlesFree article
Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin.
Sahai A, Malladi P, Pan X, Paul R, Melin-Aldana H, Green RM, Whitington PF.
Am J Physiol Gastrointest Liver Physiol. 2004 Nov;287(5):G1035-43. Epub 2004 Jul 15.PMID: 15256362 [PubMed - indexed for MEDLINE]Related articlesFree article
Leptin treatment markedly increased plasma adiponectin but barely decreased plasma resistin of ob/ob mice.
Delporte ML, El Mkadem SA, Quisquater M, Brichard SM.
Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E446-53. Epub 2004 May 4.PMID: 15126241 [PubMed - indexed for MEDLINE]Related articlesFree article
Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice.
Sun Y, Asnicar M, Saha PK, Chan L, Smith RG.
Cell Metab. 2006 May;3(5):379-86.PMID: 16679295 [PubMed - indexed for MEDLINE]Related articles
Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: analyses using mouse models and a cell line.
Luque RM, Kineman RD, Tena-Sempere M.
Endocrinology. 2007 Oct;148(10):4601-11. Epub 2007 Jun 26.PMID: 17595226 [PubMed - indexed for MEDLINE]Related articlesFree article
Wound collagen accumulation in obese hyperglycemic mice.
Goodson WH 3rd, Hunt TK.
Diabetes. 1986 Apr;35(4):491-5.PMID: 3514328 [PubMed - indexed for MEDLINE]Related articles
Altered macrophage-like functions of preadipocytes in inflammation and genetic obesity.
Cousin B, André M, Casteilla L, Pénicaud L.
J Cell Physiol. 2001 Mar;186(3):380-6.PMID: 11169977 [PubMed - indexed for MEDLINE]Related articles
Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice.
Vareniuk I, Pavlov IA, Drel VR, Lyzogubov VV, Ilnytska O, Bell SR, Tibrewala J, Groves JT, Obrosova IG.
Exp Neurol. 2007 Jun;205(2):425-36. Epub 2007 Mar 27.PMID: 17475250 [PubMed - indexed for MEDLINE]Related articles
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