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    Results: 1 to 20 of 143

    1.

    Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice.

    Klover PJ, Zimmers TA, Koniaris LG, Mooney RA.

    Diabetes. 2003 Nov;52(11):2784-9.PMID: 14578297 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Interleukin-6 depletion selectively improves hepatic insulin action in obesity.

    Klover PJ, Clementi AH, Mooney RA.

    Endocrinology. 2005 Aug;146(8):3417-27. Epub 2005 Apr 21.PMID: 15845623 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Interleukin-6 induces cellular insulin resistance in hepatocytes.

    Senn JJ, Klover PJ, Nowak IA, Mooney RA.

    Diabetes. 2002 Dec;51(12):3391-9.PMID: 12453891 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo.

    Kim HJ, Higashimori T, Park SY, Choi H, Dong J, Kim YJ, Noh HL, Cho YR, Cline G, Kim YB, Kim JK.

    Diabetes. 2004 Apr;53(4):1060-7.PMID: 15047622 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3.

    O'Connor JC, Sherry CL, Guest CB, Freund GG.

    J Immunol. 2007 Jun 1;178(11):6886-93.PMID: 17513737 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Aggravation by prostaglandin E2 of interleukin-6-dependent insulin resistance in hepatocytes.

    Henkel J, Neuschäfer-Rube F, Pathe-Neuschäfer-Rube A, Püschel GP.

    Hepatology. 2009 Sep;50(3):781-90.PMID: 19575453 [PubMed - indexed for MEDLINE]Related articles

    7.

    Irbesartan restores the in-vivo insulin signaling pathway leading to Akt activation in obese Zucker rats.

    Muñoz MC, Argentino DP, Dominici FP, Turyn D, Toblli JE.

    J Hypertens. 2006 Aug;24(8):1607-17.PMID: 16877964 [PubMed - indexed for MEDLINE]Related articles

    8.

    Short-term infusion of interleukin-6 does not induce insulin resistance in vivo or impair insulin signalling in rats.

    Rotter Sopasakis V, Larsson BM, Johansson A, Holmäng A, Smith U.

    Diabetologia. 2004 Nov;47(11):1879-87. Epub 2004 Nov 17.PMID: 15551046 [PubMed - indexed for MEDLINE]Related articles

    9.

    Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression.

    Jager J, Grémeaux T, Cormont M, Le Marchand-Brustel Y, Tanti JF.

    Endocrinology. 2007 Jan;148(1):241-51. Epub 2006 Oct 12.PMID: 17038556 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Interleukin-1alpha inhibits insulin signaling with phosphorylating insulin receptor substrate-1 on serine residues in 3T3-L1 adipocytes.

    He J, Usui I, Ishizuka K, Kanatani Y, Hiratani K, Iwata M, Bukhari A, Haruta T, Sasaoka T, Kobayashi M.

    Mol Endocrinol. 2006 Jan;20(1):114-24. Epub 2005 Sep 8.PMID: 16150868 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells.

    Weigert C, Hennige AM, Lehmann R, Brodbeck K, Baumgartner F, Schaüble M, Häring HU, Schleicher ED.

    J Biol Chem. 2006 Mar 17;281(11):7060-7. Epub 2006 Jan 17.PMID: 16418171 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.

    Hartman ME, O'Connor JC, Godbout JP, Minor KD, Mazzocco VR, Freund GG.

    J Biol Chem. 2004 Jul 2;279(27):28045-50. Epub 2004 Apr 27.PMID: 15123681 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo.

    Park E, Wong V, Guan X, Oprescu AI, Giacca A.

    J Endocrinol. 2007 Nov;195(2):323-31.PMID: 17951543 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Chronic tumor necrosis factor-alpha treatment causes insulin resistance via insulin receptor substrate-1 serine phosphorylation and suppressor of cytokine signaling-3 induction in 3T3-L1 adipocytes.

    Ishizuka K, Usui I, Kanatani Y, Bukhari A, He J, Fujisaka S, Yamazaki Y, Suzuki H, Hiratani K, Ishiki M, Iwata M, Urakaze M, Haruta T, Kobayashi M.

    Endocrinology. 2007 Jun;148(6):2994-3003. Epub 2007 Mar 22.PMID: 17379643 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells.

    Andreozzi F, Laratta E, Procopio C, Hribal ML, Sciacqua A, Perticone M, Miele C, Perticone F, Sesti G.

    Mol Cell Biol. 2007 Mar;27(6):2372-83. Epub 2007 Jan 22.PMID: 17242212 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    In vivo leptin infusion impairs insulin and leptin signalling in liver and hypothalamus.

    Benomar Y, Wetzler S, Larue-Achagiotis C, Djiane J, Tomé D, Taouis M.

    Mol Cell Endocrinol. 2005 Oct 20;242(1-2):59-66.PMID: 16150536 [PubMed - indexed for MEDLINE]Related articles

    17.

    Suppressor of cytokine signaling 3 expression and insulin resistance in skeletal muscle of obese and type 2 diabetic patients.

    Rieusset J, Bouzakri K, Chevillotte E, Ricard N, Jacquet D, Bastard JP, Laville M, Vidal H.

    Diabetes. 2004 Sep;53(9):2232-41.PMID: 15331532 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Targeted disruption of iNOS prevents LPS-induced S-nitrosation of IRbeta/IRS-1 and Akt and insulin resistance in muscle of mice.

    Carvalho-Filho MA, Ueno M, Carvalheira JB, Velloso LA, Saad MJ.

    Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E476-82. Epub 2006 Apr 25.PMID: 16638822 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Adenovirus-mediated chronic "hyper-resistinemia" leads to in vivo insulin resistance in normal rats.

    Satoh H, Nguyen MT, Miles PD, Imamura T, Usui I, Olefsky JM.

    J Clin Invest. 2004 Jul;114(2):224-31.PMID: 15254589 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance.

    Duan C, Yang H, White MF, Rui L.

    Mol Cell Biol. 2004 Sep;24(17):7435-43.PMID: 15314154 [PubMed - indexed for MEDLINE]Related articlesFree article

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