PubMed

Rapamycin has a deleterious effect on MIN-6 cells and rat and human islets.

Bell E, Cao X, Moibi JA, Greene SR, Young R, Trucco M, Gao Z, Matschinsky FM, Deng S, Markman JF, Naji A, Wolf BA.

Diabetes. 2003 Nov;52(11):2731-9.PMID: 14578291 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular endothelial growth factor as a survival factor for human islets: effect of immunosuppressive drugs.

Cross SE, Richards SK, Clark A, Benest AV, Bates DO, Mathieson PW, Johnson PR, Harper SJ, Smith RM.

Diabetologia. 2007 Jul;50(7):1423-32. Epub 2007 May 3.PMID: 17476476 [PubMed - indexed for MEDLINE]Related articles

Sirolimus toxicity and vascular endothelial growth factor release from islet and renal cell lines.

Laugharne M, Cross S, Richards S, Dawson C, Ilchyshyn L, Saleem M, Mathieson P, Smith R.

Transplantation. 2007 Jun 27;83(12):1635-8.PMID: 17589348 [PubMed - indexed for MEDLINE]Related articles

Tacrolimus impairment of insulin secretion in isolated rat islets occurs at multiple distal sites in stimulus-secretion coupling.

Uchizono Y, Iwase M, Nakamura U, Sasaki N, Goto D, Iida M.

Endocrinology. 2004 May;145(5):2264-72. Epub 2004 Feb 12.PMID: 14962991 [PubMed - indexed for MEDLINE]Related articlesFree article

Rapamycin induces autophagy in islets: relevance in islet transplantation.

Tanemura M, Saga A, Kawamoto K, Machida T, Deguchi T, Nishida T, Sawa Y, Doki Y, Mori M, Ito T.

Transplant Proc. 2009 Jan-Feb;41(1):334-8.PMID: 19249550 [PubMed - indexed for MEDLINE]Related articles

Pancreatic-derived factor (FAM3B), a novel islet cytokine, induces apoptosis of insulin-secreting beta-cells.

Cao X, Gao Z, Robert CE, Greene S, Xu G, Xu W, Bell E, Campbell D, Zhu Y, Young R, Trucco M, Markmann JF, Naji A, Wolf BA.

Diabetes. 2003 Sep;52(9):2296-303.PMID: 12941769 [PubMed - indexed for MEDLINE]Related articlesFree article

Small intestinal submucosa improves islet survival and function in vitro culture.

Xiaohui T, Wujun X, Xiaoming D, Xinlu P, Yan T, Puxun T, Xinshun F.

Transplant Proc. 2006 Jun;38(5):1552-8.PMID: 16797356 [PubMed - indexed for MEDLINE]Related articles

[Study of the effects of immunosuppressive agents on human islet cells in vitro]

Cai JQ, Tan JM, Dong WP, Wang YF, Wang JB.

Zhonghua Yi Xue Za Zhi. 2005 Mar 16;85(10):654-6. Chinese. PMID: 15932724 [PubMed - indexed for MEDLINE]Related articles

Effects of ghrelin on insulin and glucagon secretion: a study of isolated pancreatic islets and intact mice.

Salehi A, Dornonville de la Cour C, Håkanson R, Lundquist I.

Regul Pept. 2004 May 15;118(3):143-50.PMID: 15003830 [PubMed - indexed for MEDLINE]Related articles

Inhibitory effects of immunosuppressive drugs on insulin secretion from HIT-T15 cells and Wistar rat islets.

Paty BW, Harmon JS, Marsh CL, Robertson RP.

Transplantation. 2002 Feb 15;73(3):353-7.PMID: 11884930 [PubMed - indexed for MEDLINE]Related articles

Adenovirus-mediated XIAP gene transfer reverses the negative effects of immunosuppressive drugs on insulin secretion and cell viability of isolated human islets.

Hui H, Khoury N, Zhao X, Balkir L, D'Amico E, Bullotta A, Nguyen ED, Gambotto A, Perfetti R.

Diabetes. 2005 Feb;54(2):424-33.PMID: 15677500 [PubMed - indexed for MEDLINE]Related articlesFree article

[Effects of three different immunosuppressive drugs on SD rat islet cell viability]

Zhao DM, Zhang H, Chen H, Cai DH.

Di Yi Jun Yi Da Xue Xue Bao. 2003 Feb;23(2):151-2. Chinese. PMID: 12581966 [PubMed - indexed for MEDLINE]Related articles

Islet amyloid polypeptide promotes beta-cell proliferation in neonatal rat pancreatic islets.

Karlsson E, Sandler S.

Diabetologia. 2001 Aug;44(8):1015-8.PMID: 11484079 [PubMed - indexed for MEDLINE]Related articles

mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes.

Fraenkel M, Ketzinel-Gilad M, Ariav Y, Pappo O, Karaca M, Castel J, Berthault MF, Magnan C, Cerasi E, Kaiser N, Leibowitz G.

Diabetes. 2008 Apr;57(4):945-57. Epub 2008 Jan 3.PMID: 18174523 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-proinflammatory effects of sirolimus on human islet preparations.

Mita A, Ricordi C, Miki A, Barker S, Haertter R, Hashikura Y, Miyagawa S, Burke GW 3rd, Inverardi L, Ichii H.

Transplantation. 2008 Jul 15;86(1):46-53.PMID: 18622277 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of prolonged in vitro exposure to high glucose on neonatal porcine pancreatic islets.

Harb G, Korbutt GS.

J Endocrinol. 2006 Oct;191(1):37-44.PMID: 17065387 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.

Johnson D, Shepherd RM, Gill D, Gorman T, Smith DM, Dunne MJ.

Diabetes. 2007 Jun;56(6):1694-702. Epub 2007 Mar 14.PMID: 17360975 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of prolonged in vitro exposure to sulphonylureas on the function and survival of human islets.

Del Guerra S, Marselli L, Lupi R, Boggi U, Mosca F, Benzi L, Del Prato S, Marchetti P.

J Diabetes Complications. 2005 Jan-Feb;19(1):60-4.PMID: 15642492 [PubMed - indexed for MEDLINE]Related articles

Role of CYP2E1 in ketone-stimulated insulin release in pancreatic B-cells.

Murdock DJ, Clarke J, Flatt PR, Barnett YA, Barnett CR.

Biochem Pharmacol. 2004 Mar 1;67(5):875-84.PMID: 15104240 [PubMed - indexed for MEDLINE]Related articles

Influence of heme oxygenase-1 gene transfer on the viability and function of rat islets in in vitro culture.

Chen XB, Li YX, Jiao Y, Dong WP, Li G, Chen J, Tan JM.

World J Gastroenterol. 2007 Feb 21;13(7):1053-9.PMID: 17373739 [PubMed - indexed for MEDLINE]Related articlesFree article