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    Results: 1 to 20 of 269

    1.

    Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse.

    Flodström-Tullberg M, Yadav D, Hägerkvist R, Tsai D, Secrest P, Stotland A, Sarvetnick N.

    Diabetes. 2003 Nov;52(11):2696-700.PMID: 14578288 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Differences in suppressor of cytokine signaling-1 (SOCS-1) expressing islet allograft destruction in normal BALB/c and spontaneously-diabetic NOD recipient mice.

    Solomon M, Flodström-Tullberg M, Sarvetnick N.

    Transplantation. 2005 May 15;79(9):1104-9.PMID: 15880051 [PubMed - indexed for MEDLINE]Related articles

    3.

    Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.

    Chong MM, Chen Y, Darwiche R, Dudek NL, Irawaty W, Santamaria P, Allison J, Kay TW, Thomas HE.

    J Immunol. 2004 May 1;172(9):5714-21.PMID: 15100317 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma.

    Cottet S, Dupraz P, Hamburger F, Dolci W, Jaquet M, Thorens B.

    J Biol Chem. 2001 Jul 13;276(28):25862-70. Epub 2001 May 7.PMID: 11342558 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Diabetogenic potential of human pathogens uncovered in experimentally permissive beta-cells.

    Flodström M, Tsai D, Fine C, Maday A, Sarvetnick N.

    Diabetes. 2003 Aug;52(8):2025-34.PMID: 12882919 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death.

    Suk K, Kim S, Kim YH, Kim KA, Chang I, Yagita H, Shong M, Lee MS.

    J Immunol. 2001 Apr 1;166(7):4481-9.PMID: 11254704 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicity.

    Karlsen AE, Rønn SG, Lindberg K, Johannesen J, Galsgaard ED, Pociot F, Nielsen JH, Mandrup-Poulsen T, Nerup J, Billestrup N.

    Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12191-6. Epub 2001 Oct 2.PMID: 11593036 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Suppressor of cytokine signaling-1 regulates the sensitivity of pancreatic beta cells to tumor necrosis factor.

    Chong MM, Thomas HE, Kay TW.

    J Biol Chem. 2002 Aug 2;277(31):27945-52. Epub 2002 May 24.PMID: 12032139 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Molecular role of TGF-beta, secreted from a new type of CD4+ suppressor T cell, NY4.2, in the prevention of autoimmune IDDM in NOD mice.

    Han HS, Jun HS, Utsugi T, Yoon JW.

    J Autoimmun. 1997 Jun;10(3):299-307.PMID: 9218758 [PubMed - indexed for MEDLINE]Related articles

    11.

    The target cell response to cytokines governs the autoreactive T cell repertoire in the pancreas of NOD mice.

    Hultcrantz M, Jacobson S, Hill NJ, Santamaria P, Flodström-Tullberg M.

    Diabetologia. 2009 Feb;52(2):299-305. Epub 2008 Nov 25.PMID: 19031069 [PubMed - indexed for MEDLINE]Related articles

    12.

    Regulation of pancreatic beta-cell mass and proliferation by SOCS-3.

    Lindberg K, Rønn SG, Tornehave D, Richter H, Hansen JA, Rømer J, Jackerott M, Billestrup N.

    J Mol Endocrinol. 2005 Oct;35(2):231-43.PMID: 16216905 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases.

    Fujimoto M, Tsutsui H, Xinshou O, Tokumoto M, Watanabe D, Shima Y, Yoshimoto T, Hirakata H, Kawase I, Nakanishi K, Kishimoto T, Naka T.

    Int Immunol. 2004 Feb;16(2):303-14.PMID: 14734616 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells.

    Baetz A, Frey M, Heeg K, Dalpke AH.

    J Biol Chem. 2004 Dec 24;279(52):54708-15. Epub 2004 Oct 18.PMID: 15491991 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Prevention of autoimmune diabetes in NOD mice by troglitazone is associated with modulation of ICAM-1 expression on pancreatic islet cells and IFN-gamma expression in splenic T cells.

    Augstein P, Dunger A, Heinke P, Wachlin G, Berg S, Hehmke B, Salzsieder E.

    Biochem Biophys Res Commun. 2003 May 2;304(2):378-84.PMID: 12711326 [PubMed - indexed for MEDLINE]Related articles

    16.

    Target cell defense prevents the development of diabetes after viral infection.

    Flodström M, Maday A, Balakrishna D, Cleary MM, Yoshimura A, Sarvetnick N.

    Nat Immunol. 2002 Apr;3(4):373-82. Epub 2002 Mar 4.PMID: 11919579 [PubMed - indexed for MEDLINE]Related articles

    17.

    Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor alpha-induced cell death in fibroblasts.

    Morita Y, Naka T, Kawazoe Y, Fujimoto M, Narazaki M, Nakagawa R, Fukuyama H, Nagata S, Kishimoto T.

    Proc Natl Acad Sci U S A. 2000 May 9;97(10):5405-10.PMID: 10792035 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Suppressor of cytokine signaling gene expression in human pancreatic islets: modulation by cytokines.

    Santangelo C, Scipioni A, Marselli L, Marchetti P, Dotta F.

    Eur J Endocrinol. 2005 Mar;152(3):485-9.PMID: 15757867 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Mycobacterium bovis bacillus Calmette-Guérin infection promotes SOCS induction and inhibits IFN-gamma-stimulated JAK/STAT signaling in J774 macrophages.

    Imai K, Kurita-Ochiai T, Ochiai K.

    FEMS Immunol Med Microbiol. 2003 Nov 28;39(2):173-80.PMID: 14625101 [PubMed - indexed for MEDLINE]Related articles

    20.

    Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection.

    Rønn SG, Börjesson A, Bruun C, Heding PE, Frobøse H, Mandrup-Poulsen T, Karlsen AE, Rasschaert J, Sandler S, Billestrup N.

    Diabetologia. 2008 Oct;51(10):1873-82. Epub 2008 Jul 22.PMID: 18648765 [PubMed - indexed for MEDLINE]Related articles

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