PubMed

Coordinated upregulation of oxidative pathways and downregulation of lipid biosynthesis underlie obesity resistance in perilipin knockout mice: a microarray gene expression profile.

Castro-Chavez F, Yechoor VK, Saha PK, Martinez-Botas J, Wooten EC, Sharma S, O'Connell P, Taegtmeyer H, Chan L.

Diabetes. 2003 Nov;52(11):2666-74.PMID: 14578284 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic adaptations in the absence of perilipin: increased beta-oxidation and decreased hepatic glucose production associated with peripheral insulin resistance but normal glucose tolerance in perilipin-null mice.

Saha PK, Kojima H, Martinez-Botas J, Sunehag AL, Chan L.

J Biol Chem. 2004 Aug 20;279(34):35150-8. Epub 2004 Jun 14.PMID: 15197189 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice.

Martinez-Botas J, Anderson JB, Tessier D, Lapillonne A, Chang BH, Quast MJ, Gorenstein D, Chen KH, Chan L.

Nat Genet. 2000 Dec;26(4):474-9.PMID: 11101849 [PubMed - indexed for MEDLINE]Related articles

Microarrays, antiobesity and the liver.

Castro-Chávez F.

Ann Hepatol. 2004 Oct-Dec;3(4):137-45. Review.PMID: 15657555 [PubMed - indexed for MEDLINE]Related articles

Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity.

Tansey JT, Sztalryd C, Gruia-Gray J, Roush DL, Zee JV, Gavrilova O, Reitman ML, Deng CX, Li C, Kimmel AR, Londos C.

Proc Natl Acad Sci U S A. 2001 May 22;98(11):6494-9.PMID: 11371650 [PubMed - indexed for MEDLINE]Related articlesFree article

The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment.

Liang Y, She P, Wang X, Demarest K.

Metabolism. 2006 Oct;55(10):1411-9.PMID: 16979414 [PubMed - indexed for MEDLINE]Related articles

Depot-specific differences in perilipin mRNA but not protein expression in obesity.

Arvidsson E, Blomqvist L, Rydén M.

J Intern Med. 2004 May;255(5):595-601.PMID: 15078502 [PubMed - indexed for MEDLINE]Related articles

The peroxisome proliferator-activated receptor gamma regulates expression of the perilipin gene in adipocytes.

Arimura N, Horiba T, Imagawa M, Shimizu M, Sato R.

J Biol Chem. 2004 Mar 12;279(11):10070-6. Epub 2004 Jan 2.PMID: 14704148 [PubMed - indexed for MEDLINE]Related articlesFree article

Downregulation of electron transport chain genes in visceral adipose tissue in type 2 diabetes independent of obesity and possibly involving tumor necrosis factor-alpha.

Dahlman I, Forsgren M, Sjögren A, Nordström EA, Kaaman M, Näslund E, Attersand A, Arner P.

Diabetes. 2006 Jun;55(6):1792-9.PMID: 16731844 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcript profiling suggests that differential metabolic adaptation of mice to a high fat diet is associated with changes in liver to muscle lipid fluxes.

de Fourmestraux V, Neubauer H, Poussin C, Farmer P, Falquet L, Burcelin R, Delorenzi M, Thorens B.

J Biol Chem. 2004 Dec 3;279(49):50743-53. Epub 2004 Sep 17.PMID: 15377667 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility.

Lan H, Rabaglia ME, Stoehr JP, Nadler ST, Schueler KL, Zou F, Yandell BS, Attie AD.

Diabetes. 2003 Mar;52(3):688-700.PMID: 12606510 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptome of the subcutaneous adipose tissue in response to oral supplementation of type 2 Leprdb obese diabetic mice with niacin-bound chromium.

Rink C, Roy S, Khanna S, Rink T, Bagchi D, Sen CK.

Physiol Genomics. 2006 Nov 27;27(3):370-9. Epub 2006 Aug 29.PMID: 16940432 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor alpha protects against obesity-induced hepatic inflammation.

Stienstra R, Mandard S, Patsouris D, Maass C, Kersten S, Müller M.

Endocrinology. 2007 Jun;148(6):2753-63. Epub 2007 Mar 8.PMID: 17347305 [PubMed - indexed for MEDLINE]Related articlesFree article

Weight-loss-associated induction of peroxisome proliferator-activated receptor-alpha and peroxisome proliferator-activated receptor-gamma correlate with reduced atherosclerosis and improved cardiovascular function in obese insulin-resistant mice.

Verreth W, De Keyzer D, Pelat M, Verhamme P, Ganame J, Bielicki JK, Mertens A, Quarck R, Benhabilès N, Marguerie G, Mackness B, Mackness M, Ninio E, Herregods MC, Balligand JL, Holvoet P.

Circulation. 2004 Nov 16;110(20):3259-69. Epub 2004 Nov 8.PMID: 15533870 [PubMed - indexed for MEDLINE]Related articlesFree article

Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation.

Li JZ, Ye J, Xue B, Qi J, Zhang J, Zhou Z, Li Q, Wen Z, Li P.

Diabetes. 2007 Oct;56(10):2523-32. Epub 2007 Jul 23.PMID: 17646209 [PubMed - indexed for MEDLINE]Related articlesFree article

D-Serine exposure resulted in gene expression changes indicative of activation of fibrogenic pathways and down-regulation of energy metabolism and oxidative stress response.

Soto A, DelRaso NJ, Schlager JJ, Chan VT.

Toxicology. 2008 Jan 14;243(1-2):177-92. Epub 2007 Oct 23.PMID: 18061331 [PubMed - indexed for MEDLINE]Related articles

Application of DNA microarrays in the study of human obesity and type 2 diabetes.

Sun G.

OMICS. 2007 Spring;11(1):25-40. Review.PMID: 17411394 [PubMed - indexed for MEDLINE]Related articles

Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance.

Miller LD, McPhie P, Suzuki H, Kato Y, Liu ET, Cheng SY.

Genome Biol. 2004;5(5):R31. Epub 2004 Apr 29.PMID: 15128445 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-gamma.

Dalen KT, Schoonjans K, Ulven SM, Weedon-Fekjaer MS, Bentzen TG, Koutnikova H, Auwerx J, Nebb HI.

Diabetes. 2004 May;53(5):1243-52.PMID: 15111493 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression profile of omental adipose tissue in human obesity.

Gómez-Ambrosi J, Catalán V, Diez-Caballero A, Martinez-Cruz LA, Gil MJ, García-Foncillas J, Cienfuegos JA, Salvador J, Mato JM, Frühbeck G.

FASEB J. 2004 Jan;18(1):215-7. Epub 2003 Nov 20.PMID: 14630696 [PubMed - indexed for MEDLINE]Related articlesFree article