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    Results: 1 to 20 of 135

    1.

    Increased insulin sensitivity and hypoinsulinemia in APS knockout mice.

    Minami A, Iseki M, Kishi K, Wang M, Ogura M, Furukawa N, Hayashi S, Yamada M, Obata T, Takeshita Y, Nakaya Y, Bando Y, Izumi K, Moodie SA, Kajiura F, Matsumoto M, Takatsu K, Takaki S, Ebina Y.

    Diabetes. 2003 Nov;52(11):2657-65.PMID: 14578283 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes.

    Liu J, Kimura A, Baumann CA, Saltiel AR.

    Mol Cell Biol. 2002 Jun;22(11):3599-609.PMID: 11997497 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Differential role of SH2-B and APS in regulating energy and glucose homeostasis.

    Li M, Ren D, Iseki M, Takaki S, Rui L.

    Endocrinology. 2006 May;147(5):2163-70. Epub 2006 Feb 2.PMID: 16455776 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Asb6, an adipocyte-specific ankyrin and SOCS box protein, interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complex.

    Wilcox A, Katsanakis KD, Bheda F, Pillay TS.

    J Biol Chem. 2004 Sep 10;279(37):38881-8. Epub 2004 Jul 1.PMID: 15231829 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Identification of the APS protein as a novel insulin receptor substrate.

    Moodie SA, Alleman-Sposeto J, Gustafson TA.

    J Biol Chem. 1999 Apr 16;274(16):11186-93.PMID: 10196204 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice.

    Voshol PJ, Haemmerle G, Ouwens DM, Zimmermann R, Zechner R, Teusink B, Maassen JA, Havekes LM, Romijn JA.

    Endocrinology. 2003 Aug;144(8):3456-62.PMID: 12865325 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Deficiency of Cbl-b gene enhances infiltration and activation of macrophages in adipose tissue and causes peripheral insulin resistance in mice.

    Hirasaka K, Kohno S, Goto J, Furochi H, Mawatari K, Harada N, Hosaka T, Nakaya Y, Ishidoh K, Obata T, Ebina Y, Gu H, Takeda S, Kishi K, Nikawa T.

    Diabetes. 2007 Oct;56(10):2511-22. Epub 2007 Jun 29.PMID: 17601987 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Enigma interacts with adaptor protein with PH and SH2 domains to control insulin-induced actin cytoskeleton remodeling and glucose transporter 4 translocation.

    Barrès R, Grémeaux T, Gual P, Gonzalez T, Gugenheim J, Tran A, Le Marchand-Brustel Y, Tanti JF.

    Mol Endocrinol. 2006 Nov;20(11):2864-75. Epub 2006 Jun 27.PMID: 16803868 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Primary and essential role of the adaptor protein APS for recruitment of both c-Cbl and its associated protein CAP in insulin signaling.

    Ahn MY, Katsanakis KD, Bheda F, Pillay TS.

    J Biol Chem. 2004 May 14;279(20):21526-32. Epub 2004 Mar 18.PMID: 15031295 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Mas deficiency in FVB/N mice produces marked changes in lipid and glycemic metabolism.

    Santos SH, Fernandes LR, Mario EG, Ferreira AV, Pôrto LC, Alvarez-Leite JI, Botion LM, Bader M, Alenina N, Santos RA.

    Diabetes. 2008 Feb;57(2):340-7. Epub 2007 Nov 19.PMID: 18025412 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Negative regulation of insulin-stimulated mitogen-activated protein kinase signaling by Grb10.

    Langlais P, Dong LQ, Ramos FJ, Hu D, Li Y, Quon MJ, Liu F.

    Mol Endocrinol. 2004 Feb;18(2):350-8. Epub 2003 Nov 13.PMID: 14615605 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Topiramate is an insulin-sensitizing compound in vivo with direct effects on adipocytes in female ZDF rats.

    Wilkes JJ, Nelson E, Osborne M, Demarest KT, Olefsky JM.

    Am J Physiol Endocrinol Metab. 2005 Mar;288(3):E617-24. Epub 2004 Nov 9.PMID: 15536205 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    K(ATP) channel knockout mice crossbred with transgenic mice expressing a dominant-negative form of human insulin receptor have glucose intolerance but not diabetes.

    Kanezaki Y, Obata T, Matsushima R, Minami A, Yuasa T, Kishi K, Bando Y, Uehara H, Izumi K, Mitani T, Matsumoto M, Takeshita Y, Nakaya Y, Matsumoto T, Ebina Y.

    Endocr J. 2004 Apr;51(2):133-44.PMID: 15118262 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Distinct Grb10 domain requirements for effects on glucose uptake and insulin signaling.

    Mori K, Giovannone B, Smith RJ.

    Mol Cell Endocrinol. 2005 Jan 31;230(1-2):39-50.PMID: 15664450 [PubMed - indexed for MEDLINE]Related articles

    15.

    Increased serum leptin protects from adiposity despite the increased glucose uptake in white adipose tissue in mice lacking p85alpha phosphoinositide 3-kinase.

    Terauchi Y, Matsui J, Kamon J, Yamauchi T, Kubota N, Komeda K, Aizawa S, Akanuma Y, Tomita M, Kadowaki T.

    Diabetes. 2004 Sep;53(9):2261-70.PMID: 15331535 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function.

    Sørensen H, Winzell MS, Brand CL, Fosgerau K, Gelling RW, Nishimura E, Ahren B.

    Diabetes. 2006 Dec;55(12):3463-9.PMID: 17130493 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1.

    Ma LJ, Mao SL, Taylor KL, Kanjanabuch T, Guan Y, Zhang Y, Brown NJ, Swift LL, McGuinness OP, Wasserman DH, Vaughan DE, Fogo AB.

    Diabetes. 2004 Feb;53(2):336-46.PMID: 14747283 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance.

    Hazel M, Cooksey RC, Jones D, Parker G, Neidigh JL, Witherbee B, Gulve EA, McClain DA.

    Endocrinology. 2004 May;145(5):2118-28. Epub 2003 Dec 18.PMID: 14684615 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Effects of atorvastatin and pravastatin on signal transduction related to glucose uptake in 3T3L1 adipocytes.

    Takaguri A, Satoh K, Itagaki M, Tokumitsu Y, Ichihara K.

    J Pharmacol Sci. 2008 May;107(1):80-9. Epub 2008 May 9.PMID: 18469500 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    APS-mediated ubiquitination of the insulin receptor enhances its internalization, but does not induce its degradation.

    Kishi K, Mawatari K, Sakai-Wakamatsu K, Yuasa T, Wang M, Ogura-Sawa M, Nakaya Y, Hatakeyama S, Ebina Y.

    Endocr J. 2007 Feb;54(1):77-88. Epub 2006 Nov 14.PMID: 17102568 [PubMed - indexed for MEDLINE]Related articlesFree article

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