PubMed

Topographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiation.

El Sheikh SS, Domin J, Tomtitchong P, Abel P, Stamp G, Lalani EN.

BMC Clin Pathol. 2003 Oct 16;3(1):4.PMID: 14563213 [PubMed - as supplied by publisher]Related articlesFree article

The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles.

Domin J, Gaidarov I, Smith ME, Keen JH, Waterfield MD.

J Biol Chem. 2000 Apr 21;275(16):11943-50.PMID: 10766823 [PubMed - indexed for MEDLINE]Related articlesFree article

Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors.

Arcaro A, Zvelebil MJ, Wallasch C, Ullrich A, Waterfield MD, Domin J.

Mol Cell Biol. 2000 Jun;20(11):3817-30.PMID: 10805725 [PubMed - indexed for MEDLINE]Related articlesFree article

The class II phosphoinositide 3-kinase C2beta is not essential for epidermal differentiation.

Harada K, Truong AB, Cai T, Khavari PA.

Mol Cell Biol. 2005 Dec;25(24):11122-30.PMID: 16314532 [PubMed - indexed for MEDLINE]Related articlesFree article

Down-regulation of class II phosphoinositide 3-kinase alpha expression below a critical threshold induces apoptotic cell death.

Elis W, Triantafellow E, Wolters NM, Sian KR, Caponigro G, Borawski J, Gaither LA, Murphy LO, Finan PM, Mackeigan JP.

Mol Cancer Res. 2008 Apr;6(4):614-23.PMID: 18403640 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of the alpha-isoform of class II phosphoinositide 3-kinase gene expression leads to apoptotic cell death.

Kang S, Song J, Kang J, Kang H, Lee D, Lee Y, Park D.

Biochem Biophys Res Commun. 2005 Apr 1;329(1):6-10.PMID: 15721265 [PubMed - indexed for MEDLINE]Related articles

Activation of class IA PI3K stimulates DNA synthesis in human airway smooth muscle cells.

Krymskaya VP, Ammit AJ, Hoffman RK, Eszterhas AJ, Panettieri RA Jr.

Am J Physiol Lung Cell Mol Physiol. 2001 May;280(5):L1009-18.PMID: 11290526 [PubMed - indexed for MEDLINE]Related articlesFree article

Class II phosphoinositide 3-kinase alpha-isoform regulates Rho, myosin phosphatase and contraction in vascular smooth muscle.

Wang Y, Yoshioka K, Azam MA, Takuwa N, Sakurada S, Kayaba Y, Sugimoto N, Inoki I, Kimura T, Kuwaki T, Takuwa Y.

Biochem J. 2006 Mar 15;394(Pt 3):581-92.PMID: 16336212 [PubMed - indexed for MEDLINE]Related articlesFree article

The N-terminus of phosphoinositide 3-kinase-C2beta regulates lipid kinase activity and binding to clathrin.

Wheeler M, Domin J.

J Cell Physiol. 2006 Mar;206(3):586-93.PMID: 16222711 [PubMed - indexed for MEDLINE]Related articles

Essential role for class II phosphoinositide 3-kinase alpha-isoform in Ca2+-induced, Rho- and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells.

Yoshioka K, Sugimoto N, Takuwa N, Takuwa Y.

Mol Pharmacol. 2007 Mar;71(3):912-20. Epub 2006 Dec 19.PMID: 17179444 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence from bioinformatics, expression and inhibition studies of phosphoinositide-3 kinase signalling in Giardia intestinalis.

Cox SS, van der Giezen M, Tarr SJ, Crompton MR, Tovar J.

BMC Microbiol. 2006 May 18;6:45.PMID: 16707026 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

Katso R, Okkenhaug K, Ahmadi K, White S, Timms J, Waterfield MD.

Annu Rev Cell Dev Biol. 2001;17:615-75. Review.PMID: 11687500 [PubMed - indexed for MEDLINE]Related articles

Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration.

Maffucci T, Cooke FT, Foster FM, Traer CJ, Fry MJ, Falasca M.

J Cell Biol. 2005 Jun 6;169(5):789-99. Epub 2005 May 31.PMID: 15928202 [PubMed - indexed for MEDLINE]Related articlesFree article

Individual phosphoinositide 3-kinase C2alpha domain activities independently regulate clathrin function.

Gaidarov I, Zhao Y, Keen JH.

J Biol Chem. 2005 Dec 9;280(49):40766-72. Epub 2005 Oct 7.PMID: 16215232 [PubMed - indexed for MEDLINE]Related articlesFree article

The class II phosphoinositide 3-kinase PI3K-C2beta regulates cell migration by a PtdIns3P dependent mechanism.

Domin J, Harper L, Aubyn D, Wheeler M, Florey O, Haskard D, Yuan M, Zicha D.

J Cell Physiol. 2005 Dec;205(3):452-62.PMID: 16113997 [PubMed - indexed for MEDLINE]Related articles

Bone morphogenetic proteins.

Chen D, Zhao M, Mundy GR.

Growth Factors. 2004 Dec;22(4):233-41. Review.PMID: 15621726 [PubMed - indexed for MEDLINE]Related articles

Are class II phosphoinositide 3-kinases potential targets for anticancer therapies?

Traer CJ, Foster FM, Abraham SM, Fry MJ.

Bull Cancer. 2006 May 1;93(5):E53-8.PMID: 16777618 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of phosphoinositide 3-kinase C2alpha in insulin signaling.

Falasca M, Hughes WE, Dominguez V, Sala G, Fostira F, Fang MQ, Cazzolli R, Shepherd PR, James DE, Maffucci T.

J Biol Chem. 2007 Sep 21;282(38):28226-36. Epub 2007 Jul 20.PMID: 17644513 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of neuron survival through an intersectin-phosphoinositide 3'-kinase C2beta-AKT pathway.

Das M, Scappini E, Martin NP, Wong KA, Dunn S, Chen YJ, Miller SL, Domin J, O'Bryan JP.

Mol Cell Biol. 2007 Nov;27(22):7906-17. Epub 2007 Sep 17.PMID: 17875942 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct interaction of major histocompatibility complex class II-derived peptides with class Ia phosphoinositide 3-kinase results in dose-dependent stimulatory effects.

Foukas LC, Panayotou G, Shepherd PR.

J Biol Chem. 2004 Feb 27;279(9):7505-11. Epub 2003 Dec 3.PMID: 14660637 [PubMed - indexed for MEDLINE]Related articlesFree article