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    Results: 1 to 20 of 226

    1.

    Kir6.2 polymorphisms sensitize beta-cell ATP-sensitive potassium channels to activation by acyl CoAs: a possible cellular mechanism for increased susceptibility to type 2 diabetes?

    Riedel MJ, Boora P, Steckley D, de Vries G, Light PE.

    Diabetes. 2003 Oct;52(10):2630-5.PMID: 14514649 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Saturated and cis/trans unsaturated acyl CoA esters differentially regulate wild-type and polymorphic beta-cell ATP-sensitive K+ channels.

    Riedel MJ, Light PE.

    Diabetes. 2005 Jul;54(7):2070-9.PMID: 15983208 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes.

    Bränström R, Aspinwall CA, Välimäki S, Ostensson CG, Tibell A, Eckhard M, Brandhorst H, Corkey BE, Berggren PO, Larsson O.

    Diabetologia. 2004 Feb;47(2):277-83. Epub 2004 Jan 23.PMID: 14740158 [PubMed - indexed for MEDLINE]Related articles

    4.

    Acyl coenzyme A esters differentially activate cardiac and beta-cell adenosine triphosphate-sensitive potassium channels in a side-chain length-specific manner.

    Fox JE, Magga J, Giles WR, Light PE.

    Metabolism. 2003 Oct;52(10):1313-9.PMID: 14564684 [PubMed - indexed for MEDLINE]Related articles

    5.

    Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel.

    Bränström R, Leibiger IB, Leibiger B, Corkey BE, Berggren PO, Larsson O.

    J Biol Chem. 1998 Nov 20;273(47):31395-400.PMID: 9813050 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA.

    Gribble FM, Proks P, Corkey BE, Ashcroft FM.

    J Biol Chem. 1998 Oct 9;273(41):26383-7.PMID: 9756869 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults.

    Tarasov AI, Nicolson TJ, Riveline JP, Taneja TK, Baldwin SA, Baldwin JM, Charpentier G, Gautier JF, Froguel P, Vaxillaire M, Rutter GA.

    Diabetes. 2008 Jun;57(6):1595-604. Epub 2008 Mar 17.PMID: 18346985 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Current status of the E23K Kir6.2 polymorphism: implications for type-2 diabetes.

    Riedel MJ, Steckley DC, Light PE.

    Hum Genet. 2005 Feb;116(3):133-45. Epub 2004 Nov 23. Review.PMID: 15565284 [PubMed - indexed for MEDLINE]Related articles

    9.

    Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif.

    Bränström R, Leibiger IB, Leibiger B, Klement G, Nilsson J, Arhem P, Aspinwall CA, Corkey BE, Larsson O, Berggren PO.

    Diabetologia. 2007 Aug;50(8):1670-7. Epub 2007 May 24.PMID: 17522836 [PubMed - indexed for MEDLINE]Related articles

    10.

    Molecular biology of adenosine triphosphate-sensitive potassium channels.

    Aguilar-Bryan L, Bryan J.

    Endocr Rev. 1999 Apr;20(2):101-35. Review.PMID: 10204114 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Elevation in intracellular long-chain acyl-coenzyme A esters lead to reduced beta-cell excitability via activation of adenosine 5'-triphosphate-sensitive potassium channels.

    Webster NJ, Searle GJ, Lam PP, Huang YC, Riedel MJ, Harb G, Gaisano HY, Holt A, Light PE.

    Endocrinology. 2008 Jul;149(7):3679-87. Epub 2008 Mar 27.PMID: 18372336 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Effect of repaglinide on cloned beta cell, cardiac and smooth muscle types of ATP-sensitive potassium channels.

    Dabrowski M, Wahl P, Holmes WE, Ashcroft FM.

    Diabetologia. 2001 Jun;44(6):747-56.PMID: 11440368 [PubMed - indexed for MEDLINE]Related articles

    13.

    Molecular mechanisms of the inhibitory effects of bupivacaine, levobupivacaine, and ropivacaine on sarcolemmal adenosine triphosphate-sensitive potassium channels in the cardiovascular system.

    Kawano T, Oshita S, Takahashi A, Tsutsumi Y, Tomiyama Y, Kitahata H, Kuroda Y, Nakaya Y.

    Anesthesiology. 2004 Aug;101(2):390-8.PMID: 15277922 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Iptakalim, a vascular ATP-sensitive potassium (KATP) channel opener, closes rat pancreatic beta-cell KATP channels and increases insulin release.

    Misaki N, Mao X, Lin YF, Suga S, Li GH, Liu Q, Chang Y, Wang H, Wakui M, Wu J.

    J Pharmacol Exp Ther. 2007 Aug;322(2):871-8. Epub 2007 May 23.PMID: 17522344 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Evidence for a unique long chain acyl-CoA ester binding site on the ATP-regulated potassium channel in mouse pancreatic beta cells.

    Bränström R, Corkey BE, Berggren PO, Larsson O.

    J Biol Chem. 1997 Jul 11;272(28):17390-4.PMID: 9211879 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Functional effects of naturally occurring KCNJ11 mutations causing neonatal diabetes on cloned cardiac KATP channels.

    Tammaro P, Proks P, Ashcroft FM.

    J Physiol. 2006 Feb 15;571(Pt 1):3-14. Epub 2005 Dec 8.PMID: 16339180 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Cytoplasmic terminus domains of Kir6.x confer different nucleotide-dependent gating on the ATP-sensitive K+ channel.

    Takano M, Xie LH, Otani H, Horie M.

    J Physiol. 1998 Oct 15;512 ( Pt 2):395-406.PMID: 9763630 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Sulfonylurea receptors type 1 and 2A randomly assemble to form heteromeric KATP channels of mixed subunit composition.

    Chan KW, Wheeler A, Csanády L.

    J Gen Physiol. 2008 Jan;131(1):43-58. Epub 2007 Dec 17.PMID: 18079561 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Differential effects of etomidate and midazolam on vascular adenosine triphosphate-sensitive potassium channels: isometric tension and patch clamp studies.

    Nakamura A, Kawahito S, Kawano T, Nazari H, Takahashi A, Kitahata H, Nakaya Y, Oshita S.

    Anesthesiology. 2007 Mar;106(3):515-22.PMID: 17325510 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    A novel KCNJ11 mutation associated with congenital hyperinsulinism reduces the intrinsic open probability of beta-cell ATP-sensitive potassium channels.

    Lin YW, MacMullen C, Ganguly A, Stanley CA, Shyng SL.

    J Biol Chem. 2006 Feb 3;281(5):3006-12. Epub 2005 Dec 6.PMID: 16332676 [PubMed - indexed for MEDLINE]Related articlesFree article

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