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    Results: 1 to 20 of 298

    1.

    Inhibition of net HepG2 cell apolipoprotein B secretion by the citrus flavonoid naringenin involves activation of phosphatidylinositol 3-kinase, independent of insulin receptor substrate-1 phosphorylation.

    Borradaile NM, de Dreu LE, Huff MW.

    Diabetes. 2003 Oct;52(10):2554-61.PMID: 14514640 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor.

    Allister EM, Mulvihill EE, Barrett PH, Edwards JY, Carter LP, Huff MW.

    J Lipid Res. 2008 Oct;49(10):2218-29. Epub 2008 Jun 27.PMID: 18587069 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes.

    Allister EM, Borradaile NM, Edwards JY, Huff MW.

    Diabetes. 2005 Jun;54(6):1676-83.PMID: 15919788 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes.

    Matsumoto M, Ogawa W, Teshigawara K, Inoue H, Miyake K, Sakaue H, Kasuga M.

    Diabetes. 2002 Jun;51(6):1672-80.PMID: 12031952 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Hepatocyte apoB-containing lipoprotein secretion is decreased by the grapefruit flavonoid, naringenin, via inhibition of MTP-mediated microsomal triglyceride accumulation.

    Borradaile NM, de Dreu LE, Barrett PH, Behrsin CD, Huff MW.

    Biochemistry. 2003 Feb 11;42(5):1283-91.PMID: 12564931 [PubMed - indexed for MEDLINE]Related articles

    6.

    Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins.

    Qiu W, Federico L, Naples M, Avramoglu RK, Meshkani R, Zhang J, Tsai J, Hussain M, Dai K, Iqbal J, Kontos CD, Horie Y, Suzuki A, Adeli K.

    Hepatology. 2008 Dec;48(6):1799-809.PMID: 19026012 [PubMed - indexed for MEDLINE]Related articles

    7.

    Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP.

    Wilcox LJ, Borradaile NM, de Dreu LE, Huff MW.

    J Lipid Res. 2001 May;42(5):725-34.PMID: 11352979 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins.

    Basciano H, Miller A, Baker C, Naples M, Adeli K.

    Am J Physiol Gastrointest Liver Physiol. 2009 Aug;297(2):G323-32. Epub 2009 Jun 4.PMID: 19497957 [PubMed - indexed for MEDLINE]Related articles

    9.

    Role of IRS-3 in the insulin signaling of IRS-1-deficient brown adipocytes.

    Arribas M, Valverde AM, Benito M.

    J Biol Chem. 2003 Nov 14;278(46):45189-99. Epub 2003 Aug 27.PMID: 12944402 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Essential role of insulin-like growth factor I receptor in insulin-induced fetal brown adipocyte differentiation.

    Mur C, Arribas M, Benito M, Valverde AM.

    Endocrinology. 2003 Feb;144(2):581-93.PMID: 12538620 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters.

    Borradaile NM, de Dreu LE, Barrett PH, Huff MW.

    J Lipid Res. 2002 Sep;43(9):1544-54.PMID: 12235187 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance.

    Mulvihill EE, Allister EM, Sutherland BG, Telford DE, Sawyez CG, Edwards JY, Markle JM, Hegele RA, Huff MW.

    Diabetes. 2009 Oct;58(10):2198-210. Epub 2009 Jul 10.PMID: 19592617 [PubMed - indexed for MEDLINE]Related articles

    13.

    Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins.

    Liu YF, Paz K, Herschkovitz A, Alt A, Tennenbaum T, Sampson SR, Ohba M, Kuroki T, LeRoith D, Zick Y.

    J Biol Chem. 2001 Apr 27;276(17):14459-65. Epub 2001 Jan 29.PMID: 11278339 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice.

    Ma KL, Ruan XZ, Powis SH, Chen Y, Moorhead JF, Varghese Z.

    Hepatology. 2008 Sep;48(3):770-81.PMID: 18752326 [PubMed - indexed for MEDLINE]Related articles

    15.

    Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFkappaB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance.

    Sajan MP, Standaert ML, Rivas J, Miura A, Kanoh Y, Soto J, Taniguchi CM, Kahn CR, Farese RV.

    Diabetologia. 2009 Jun;52(6):1197-207. Epub 2009 Apr 9.PMID: 19357831 [PubMed - indexed for MEDLINE]Related articles

    16.

    Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade.

    Kotzka J, Müller-Wieland D, Roth G, Kremer L, Munck M, Schürmann S, Knebel B, Krone W.

    J Lipid Res. 2000 Jan;41(1):99-108.PMID: 10627507 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Restoration of sterol-regulatory-element-binding protein-1c gene expression in HepG2 cells by peroxisome-proliferator-activated receptor-gamma co-activator-1alpha.

    Oberkofler H, Schraml E, Krempler F, Patsch W.

    Biochem J. 2004 Jul 15;381(Pt 2):357-63.PMID: 15084148 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Insulin regulation of sterol regulatory element-binding protein-1 expression in L-6 muscle cells and 3T3 L1 adipocytes.

    Nadeau KJ, Leitner JW, Gurerich I, Draznin B.

    J Biol Chem. 2004 Aug 13;279(33):34380-7. Epub 2004 Jun 8.PMID: 15187085 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP).

    You M, Fischer M, Deeg MA, Crabb DW.

    J Biol Chem. 2002 Aug 9;277(32):29342-7. Epub 2002 May 29.PMID: 12036955 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Interaction between growth hormone and insulin in the regulation of lipoprotein metabolism in the rat.

    Frick F, Lindén D, Améen C, Edén S, Mode A, Oscarsson J.

    Am J Physiol Endocrinol Metab. 2002 Nov;283(5):E1023-31.PMID: 12376331 [PubMed - indexed for MEDLINE]Related articlesFree article

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