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    Results: 1 to 20 of 4722

    1.

    A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes.

    Kashyap S, Belfort R, Gastaldelli A, Pratipanawatr T, Berria R, Pratipanawatr W, Bajaj M, Mandarino L, DeFronzo R, Cusi K.

    Diabetes. 2003 Oct;52(10):2461-74.PMID: 14514628 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Effects on insulin secretion and insulin action of a 48-h reduction of plasma free fatty acids with acipimox in nondiabetic subjects genetically predisposed to type 2 diabetes.

    Cusi K, Kashyap S, Gastaldelli A, Bajaj M, Cersosimo E.

    Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1775-81. Epub 2007 Feb 13.PMID: 17299078 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Discordant effects of a chronic physiological increase in plasma FFA on insulin signaling in healthy subjects with or without a family history of type 2 diabetes.

    Kashyap SR, Belfort R, Berria R, Suraamornkul S, Pratipranawatr T, Finlayson J, Barrentine A, Bajaj M, Mandarino L, DeFronzo R, Cusi K.

    Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E537-46. Epub 2004 May 4.PMID: 15126243 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Effects of fatty acids and ketone bodies on basal insulin secretion in type 2 diabetes.

    Boden G, Chen X.

    Diabetes. 1999 Mar;48(3):577-83.PMID: 10078559 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Free fatty acid-mediated impairment of glucose-stimulated insulin secretion in nondiabetic Oji-Cree individuals from the Sandy Lake community of Ontario, Canada: a population at very high risk for developing type 2 diabetes.

    Carpentier A, Zinman B, Leung N, Giacca A, Hanley AJ, Harris SB, Hegele RA, Lewis GF.

    Diabetes. 2003 Jun;52(6):1485-95.PMID: 12765961 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Insulin secretion after short- and long-term low-grade free fatty acid infusion in men with increased risk of developing type 2 diabetes.

    Storgaard H, Jensen CB, Vaag AA, Vølund A, Madsbad S.

    Metabolism. 2003 Jul;52(7):885-94.PMID: 12870166 [PubMed - indexed for MEDLINE]Related articles

    7.

    Sustained reduction in plasma free fatty acid concentration improves insulin action without altering plasma adipocytokine levels in subjects with strong family history of type 2 diabetes.

    Bajaj M, Suraamornkul S, Kashyap S, Cusi K, Mandarino L, DeFronzo RA.

    J Clin Endocrinol Metab. 2004 Sep;89(9):4649-55.PMID: 15356076 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes.

    Carpentier A, Mittelman SD, Bergman RN, Giacca A, Lewis GF.

    Diabetes. 2000 Mar;49(3):399-408.PMID: 10868961 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Dose-response effect of elevated plasma free fatty acid on insulin signaling.

    Belfort R, Mandarino L, Kashyap S, Wirfel K, Pratipanawatr T, Berria R, Defronzo RA, Cusi K.

    Diabetes. 2005 Jun;54(6):1640-8.PMID: 15919784 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Lack of effect of a physiological elevation of plasma non-esterified fatty acid levels on insulin secretion.

    Frias JP, Basabe L, Macaraeg G, Kruszynska YT.

    Diabetes Metab. 2000 Apr;26(2):133-9.PMID: 10804328 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects.

    Halberstam M, Cohen N, Shlimovich P, Rossetti L, Shamoon H.

    Diabetes. 1996 May;45(5):659-66. Erratum in: Diabetes 1996 Sep;45(9):1285. PMID: 8621019 [PubMed - indexed for MEDLINE]Related articles

    12.

    Elevation of plasma fatty acids by ten-hour intralipid infusion has no effect on basal or glucose-stimulated insulin secretion in normal man.

    Amery CM, Round RA, Smith JM, Nattrass M.

    Metabolism. 2000 Apr;49(4):450-4.PMID: 10778867 [PubMed - indexed for MEDLINE]Related articles

    13.

    Effects of free fatty acid elevation on postabsorptive endogenous glucose production and gluconeogenesis in humans.

    Roden M, Stingl H, Chandramouli V, Schumann WC, Hofer A, Landau BR, Nowotny P, Waldhäusl W, Shulman GI.

    Diabetes. 2000 May;49(5):701-7.PMID: 10905476 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Prolonged elevation of plasma free fatty acids desensitizes the insulin secretory response to glucose in vivo in rats.

    Mason TM, Goh T, Tchipashvili V, Sandhu H, Gupta N, Lewis GF, Giacca A.

    Diabetes. 1999 Mar;48(3):524-30.PMID: 10078552 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Metabolic defects in lean nondiabetic offspring of NIDDM parents: a cross-sectional study.

    Perseghin G, Ghosh S, Gerow K, Shulman GI.

    Diabetes. 1997 Jun;46(6):1001-9.PMID: 9166672 [PubMed - indexed for MEDLINE]Related articles

    16.

    Improved glycemic control and enhanced insulin sensitivity in type 2 diabetic subjects treated with pioglitazone.

    Miyazaki Y, Mahankali A, Matsuda M, Glass L, Mahankali S, Ferrannini E, Cusi K, Mandarino LJ, DeFronzo RA.

    Diabetes Care. 2001 Apr;24(4):710-9.PMID: 11315836 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Glucose-mediated glucose disposal in insulin-resistant normoglycemic relatives of type 2 diabetic patients.

    Henriksen JE, Levin K, Thye-Rønn P, Alford F, Hother-Nielsen O, Holst JJ, Beck-Nielsen H.

    Diabetes. 2000 Jul;49(7):1209-18.PMID: 10909980 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Young, low-birth-weight men are not more susceptible to the diabetogenic effects of a prolonged free fatty acid exposure than matched controls.

    Jensen CB, Storgaard H, Holst JJ, Dela F, Madsbad S, Vaag A.

    Metabolism. 2005 Oct;54(10):1398-406.PMID: 16154442 [PubMed - indexed for MEDLINE]Related articles

    19.

    Effects of a 48-h fat infusion on insulin secretion and glucose utilization.

    Boden G, Chen X, Rosner J, Barton M.

    Diabetes. 1995 Oct;44(10):1239-42.PMID: 7556964 [PubMed - indexed for MEDLINE]Related articles

    20.

    Insulin secretion, insulin sensitivity, and hepatic insulin extraction in first-degree relatives of type 2 diabetic patients.

    Pimenta WP, Santos ML, Cruz NS, Aragon FF, Padovani CR, Gerich JE.

    Braz J Med Biol Res. 2003 Mar;36(3):301-8. Epub 2003 Mar 7.PMID: 12640493 [PubMed - indexed for MEDLINE]Related articlesFree article

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