Myeloid leukemia in children 4 years or older with Down syndrome often lacks GATA1 mutation and cytogenetics and risk of relapse are more akin to sporadic AML.
Hasle H, Abrahamsson J, Arola M, Karow A, O'Marcaigh A, Reinhardt D, Webb DK, van Wering E, Zeller B, Zwaan CM, Vyas P.
Leukemia. 2008 Jul;22(7):1428-30. Epub 2007 Dec 6. No abstract available. PMID: 18059480 [PubMed - indexed for MEDLINE]Related articles