PubMed

Peroxisome proliferator-activated receptor (PPAR)-alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation.

Koh EH, Kim MS, Park JY, Kim HS, Youn JY, Park HS, Youn JH, Lee KU.

Diabetes. 2003 Sep;52(9):2331-7.PMID: 12941773 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential influences of peroxisome proliferator-activated receptors gamma and -alpha on food intake and energy homeostasis.

Larsen PJ, Jensen PB, Sørensen RV, Larsen LK, Vrang N, Wulff EM, Wassermann K.

Diabetes. 2003 Sep;52(9):2249-59.PMID: 12941763 [PubMed - indexed for MEDLINE]Related articlesFree article

Fenofibrate lowers abdominal and skeletal adiposity and improves insulin sensitivity in OLETF rats.

Lee HJ, Choi SS, Park MK, An YJ, Seo SY, Kim MC, Hong SH, Hwang TH, Kang DY, Garber AJ, Kim DK.

Biochem Biophys Res Commun. 2002 Aug 16;296(2):293-9.PMID: 12163016 [PubMed - indexed for MEDLINE]Related articles

Effect of PPAR-alpha and -gamma agonist on the expression of visfatin, adiponectin, and TNF-alpha in visceral fat of OLETF rats.

Choi KC, Ryu OH, Lee KW, Kim HY, Seo JA, Kim SG, Kim NH, Choi DS, Baik SH, Choi KM.

Biochem Biophys Res Commun. 2005 Oct 28;336(3):747-53.PMID: 16157299 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor (PPAR)-alpha agonism prevents the onset of type 2 diabetes in Zucker diabetic fatty rats: A comparison with PPAR gamma agonism.

Bergeron R, Yao J, Woods JW, Zycband EI, Liu C, Li Z, Adams A, Berger JP, Zhang BB, Moller DE, Doebber TW.

Endocrinology. 2006 Sep;147(9):4252-62. Epub 2006 May 25.PMID: 16728496 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of peroxisome proliferator activator receptor-alpha and gamma ligands on intimal hyperplasia after balloon catheter-induced vascular injury in Zucker rats.

Desouza CV, Murthy SN, Diez J, Dunne B, Matta AS, Fonseca VA, McNamara DB.

J Cardiovasc Pharmacol Ther. 2003 Dec;8(4):297-305.PMID: 14740079 [PubMed - indexed for MEDLINE]Related articles

Left-ventricular diastolic dysfunction may be prevented by chronic treatment with PPAR-alpha or -gamma agonists in a type 2 diabetic animal model.

Kim SK, Zhao ZS, Lee YJ, Lee KE, Kang SM, Choi D, Lim SK, Chung N, Lee HC, Cha BS.

Diabetes Metab Res Rev. 2003 Nov-Dec;19(6):487-93.PMID: 14648808 [PubMed - indexed for MEDLINE]Related articles

A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats.

Murakami K, Tobe K, Ide T, Mochizuki T, Ohashi M, Akanuma Y, Yazaki Y, Kadowaki T.

Diabetes. 1998 Dec;47(12):1841-7.PMID: 9836514 [PubMed - indexed for MEDLINE]Related articlesFree article

Depot-specific regulation of perilipin by rosiglitazone in a diabetic animal model.

Kim HJ, Jung TW, Kang ES, Kim DJ, Ahn CW, Lee KW, Lee HC, Cha BS.

Metabolism. 2007 May;56(5):676-85.PMID: 17445544 [PubMed - indexed for MEDLINE]Related articles

Rosiglitazone aggravates nonalcoholic Fatty pancreatic disease in C57BL/6 mice fed high-fat and high-sucrose diet.

Fernandes-Santos C, Evangelista Carneiro R, de Souza Mendonca L, Barbosa Aguila M, Mandarim-de-Lacerda CA.

Pancreas. 2009 Apr;38(3):e80-6.PMID: 19214135 [PubMed - indexed for MEDLINE]Related articles

Dual PPARalpha /gamma activation provides enhanced improvement of insulin sensitivity and glycemic control in ZDF rats.

Brand CL, Sturis J, Gotfredsen CF, Fleckner J, Fledelius C, Hansen BF, Andersen B, Ye JM, Sauerberg P, Wassermann K.

Am J Physiol Endocrinol Metab. 2003 Apr;284(4):E841-54. Epub 2002 Dec 10.PMID: 12475752 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of PPAR-alpha agonist fenofibrate on insulin sensitivity and selected adipose tissue-derived hormones in obese women with type 2 diabetes.

Anderlová K, Dolezalová R, Housová J, Bosanská L, Haluzíková D, Kremen J, Skrha J, Haluzík M.

Physiol Res. 2007;56(5):579-86. Epub 2006 Dec 19.PMID: 17184146 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator activated receptor (PPAR)alpha agonists inhibit hypertrophy of neonatal rat cardiac myocytes.

Liang F, Wang F, Zhang S, Gardner DG.

Endocrinology. 2003 Sep;144(9):4187-94.PMID: 12933694 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents.

Singh Ahuja H, Liu S, Crombie DL, Boehm M, Leibowitz MD, Heyman RA, Depre C, Nagy L, Tontonoz P, Davies PJ.

Mol Pharmacol. 2001 Apr;59(4):765-73.PMID: 11259621 [PubMed - indexed for MEDLINE]Related articlesFree article

Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues.

Way JM, Harrington WW, Brown KK, Gottschalk WK, Sundseth SS, Mansfield TA, Ramachandran RK, Willson TM, Kliewer SA.

Endocrinology. 2001 Mar;142(3):1269-77.PMID: 11181544 [PubMed - indexed for MEDLINE]Related articlesFree article

Bezafibrate on lipids and glucose metabolism in obese diabetic Otsuka Long-Evans Tokushima fatty rats.

Jia D, Yamamoto M, Otani M, Otsuki M.

Metabolism. 2004 Apr;53(4):405-13.PMID: 15045684 [PubMed - indexed for MEDLINE]Related articles

Fenofibrate prevents Rosiglitazone-induced body weight gain in ob/ob mice.

Carmona MC, Louche K, Nibbelink M, Prunet B, Bross A, Desbazeille M, Dacquet C, Renard P, Casteilla L, Pénicaud L.

Int J Obes (Lond). 2005 Jul;29(7):864-71.PMID: 15917863 [PubMed - indexed for MEDLINE]Related articles

Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the liver of obese diabetic mice.

Memon RA, Tecott LH, Nonogaki K, Beigneux A, Moser AH, Grunfeld C, Feingold KR.

Endocrinology. 2000 Nov;141(11):4021-31.PMID: 11089532 [PubMed - indexed for MEDLINE]Related articlesFree article

A peroxisome proliferator-activated receptor alpha/gamma dual agonist with a unique in vitro profile and potent glucose and lipid effects in rodent models of type 2 diabetes and dyslipidemia.

Reifel-Miller A, Otto K, Hawkins E, Barr R, Bensch WR, Bull C, Dana S, Klausing K, Martin JA, Rafaeloff-Phail R, Rafizadeh-Montrose C, Rhodes G, Robey R, Rojo I, Rungta D, Snyder D, Wilbur K, Zhang T, Zink R, Warshawsky A, Brozinick JT.

Mol Endocrinol. 2005 Jun;19(6):1593-605. Epub 2005 Apr 14.PMID: 15831517 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor (PPAR)-alpha activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR-gamma activation.

Ye JM, Doyle PJ, Iglesias MA, Watson DG, Cooney GJ, Kraegen EW.

Diabetes. 2001 Feb;50(2):411-7.PMID: 11272155 [PubMed - indexed for MEDLINE]Related articlesFree article