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    Results: 1 to 20 of 266

    1.

    Pancreatic-derived factor (FAM3B), a novel islet cytokine, induces apoptosis of insulin-secreting beta-cells.

    Cao X, Gao Z, Robert CE, Greene S, Xu G, Xu W, Bell E, Campbell D, Zhu Y, Young R, Trucco M, Markmann JF, Naji A, Wolf BA.

    Diabetes. 2003 Sep;52(9):2296-303.PMID: 12941769 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Structure-function studies of PANDER, an islet specific cytokine inducing cell death of insulin-secreting beta cells.

    Yang J, Gao Z, Robert CE, Burkhardt BR, Gaweska H, Wagner A, Wu J, Greene SR, Young RA, Wolf BA.

    Biochemistry. 2005 Aug 30;44(34):11342-52.PMID: 16114871 [PubMed - indexed for MEDLINE]Related articles

    3.

    Effects of overexpression of pancreatic derived factor (FAM3B) in isolated mouse islets and insulin-secreting betaTC3 cells.

    Cao X, Yang J, Burkhardt BR, Gao Z, Wong RK, Greene SR, Wu J, Wolf BA.

    Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E543-50. Epub 2005 May 31.PMID: 15928025 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Mechanisms of glucose-induced secretion of pancreatic-derived factor (PANDER or FAM3B) in pancreatic beta-cells.

    Yang J, Robert CE, Burkhardt BR, Young RA, Wu J, Gao Z, Wolf BA.

    Diabetes. 2005 Nov;54(11):3217-28.PMID: 16249448 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Tissue-specific and glucose-responsive expression of the pancreatic derived factor (PANDER) promoter.

    Burkhardt BR, Yang MC, Robert CE, Greene SR, McFadden KK, Yang J, Wu J, Gao Z, Wolf BA.

    Biochim Biophys Acta. 2005 Sep 25;1730(3):215-25.PMID: 16102856 [PubMed - indexed for MEDLINE]Related articles

    6.

    Interferon-gamma-induced regulation of the pancreatic derived cytokine FAM3B in islets and insulin-secreting betaTC3 cells.

    Xu W, Gao Z, Wu J, Wolf BA.

    Mol Cell Endocrinol. 2005 Aug 30;240(1-2):74-81.PMID: 16006032 [PubMed - indexed for MEDLINE]Related articles

    7.

    Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress.

    Piro S, Anello M, Di Pietro C, Lizzio MN, Patanè G, Rabuazzo AM, Vigneri R, Purrello M, Purrello F.

    Metabolism. 2002 Oct;51(10):1340-7.PMID: 12370856 [PubMed - indexed for MEDLINE]Related articles

    8.

    PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21).

    Burkhardt BR, Greene SR, White P, Wong RK, Brestelli JE, Yang J, Robert CE, Brusko TM, Wasserfall CH, Wu J, Atkinson MA, Gao Z, Kaestner KH, Wolf BA.

    Gene. 2006 Mar 15;369:134-41. Epub 2006 Jan 18.PMID: 16412588 [PubMed - indexed for MEDLINE]Related articles

    9.

    Mechanisms of glucose-induced expression of pancreatic-derived factor in pancreatic beta-cells.

    Wang O, Cai K, Pang S, Wang T, Qi D, Zhu Q, Ni Z, Le Y.

    Endocrinology. 2008 Feb;149(2):672-80. Epub 2007 Oct 25.PMID: 17962352 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Expression of calbindin-D(28k) in a pancreatic islet beta-cell line protects against cytokine-induced apoptosis and necrosis.

    Rabinovitch A, Suarez-Pinzon WL, Sooy K, Strynadka K, Christakos S.

    Endocrinology. 2001 Aug;142(8):3649-55.PMID: 11459814 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Insulin secretion, DNA damage, and apoptosis in human and rat islets of Langerhans following exposure to nitric oxide, peroxynitrite, and cytokines.

    Hadjivassiliou V, Green MH, James RF, Swift SM, Clayton HA, Green IC.

    Nitric Oxide. 1998;2(6):429-41.PMID: 10342486 [PubMed - indexed for MEDLINE]Related articles

    12.

    Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress.

    Kharroubi I, Ladrière L, Cardozo AK, Dogusan Z, Cnop M, Eizirik DL.

    Endocrinology. 2004 Nov;145(11):5087-96. Epub 2004 Aug 5.PMID: 15297438 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    The c-Jun N-terminal kinase JNK participates in cytokine- and isolation stress-induced rat pancreatic islet apoptosis.

    Abdelli S, Abderrahmani A, Hering BJ, Beckmann JS, Bonny C.

    Diabetologia. 2007 Aug;50(8):1660-9. Epub 2007 Jun 9.PMID: 17558486 [PubMed - indexed for MEDLINE]Related articles

    14.

    Heat shock protein 27 overexpression mitigates cytokine-induced islet apoptosis and streptozotocin-induced diabetes.

    Dai T, Patel-Chamberlin M, Natarajan R, Todorov I, Ma J, LaPage J, Phillips L, Nast CC, Becerra D, Chuang P, Tong L, de Belleroche J, Wells DJ, Wang Y, Adler SG.

    Endocrinology. 2009 Jul;150(7):3031-9. Epub 2009 Mar 26.PMID: 19325007 [PubMed - indexed for MEDLINE]Related articles

    15.

    Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity.

    Chen M, Yang ZD, Smith KM, Carter JD, Nadler JL.

    Diabetologia. 2005 Mar;48(3):486-95. Epub 2005 Feb 24.PMID: 15729574 [PubMed - indexed for MEDLINE]Related articles

    16.

    Lisofylline, a novel antiinflammatory agent, protects pancreatic beta-cells from proinflammatory cytokine damage by promoting mitochondrial metabolism.

    Chen M, Yang Z, Wu R, Nadler JL.

    Endocrinology. 2002 Jun;143(6):2341-8.PMID: 12021199 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    The acquisition of an insulin-secreting phenotype by HGF-treated rat pancreatic ductal cells (ARIP) is associated with the development of susceptibility to cytokine-induced apoptosis.

    Anastasi E, Santangelo C, Bulotta A, Dotta F, Argenti B, Mincione C, Gulino A, Maroder M, Perfetti R, Di Mario U.

    J Mol Endocrinol. 2005 Apr;34(2):367-76.PMID: 15821103 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells.

    Haefliger JA, Tawadros T, Meylan L, Gurun SL, Roehrich ME, Martin D, Thorens B, Waeber G.

    J Cell Sci. 2003 Apr 15;116(Pt 8):1463-9.PMID: 12640031 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet beta-cells.

    Laychock SG, Sessanna SM, Lin MH, Mastrandrea LD.

    Endocrinology. 2006 Oct;147(10):4705-12. Epub 2006 Jun 22.PMID: 16794003 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Role of cyclooxygenase-2 in cytokine-induced beta-cell dysfunction and damage by isolated rat and human islets.

    Heitmeier MR, Kelly CB, Ensor NJ, Gibson KA, Mullis KG, Corbett JA, Maziasz TJ.

    J Biol Chem. 2004 Dec 17;279(51):53145-51. Epub 2004 Oct 7.PMID: 15471850 [PubMed - indexed for MEDLINE]Related articlesFree article

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