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Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine.

Babaei-Jadidi R, Karachalias N, Ahmed N, Battah S, Thornalley PJ.

Diabetes. 2003 Aug;52(8):2110-20.PMID: 12882930 [PubMed - indexed for MEDLINE]Related articlesFree article

The potential role of thiamine (vitamin B1) in diabetic complications.

Thornalley PJ.

Curr Diabetes Rev. 2005 Aug;1(3):287-98. Review.PMID: 18220605 [PubMed - indexed for MEDLINE]Related articles

Regulation of intracellular glucose and polyol pathway by thiamine and benfotiamine in vascular cells cultured in high glucose.

Berrone E, Beltramo E, Solimine C, Ape AU, Porta M.

J Biol Chem. 2006 Apr 7;281(14):9307-13. Epub 2006 Feb 1.PMID: 16452468 [PubMed - indexed for MEDLINE]Related articlesFree article

Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy.

Hammes HP, Du X, Edelstein D, Taguchi T, Matsumura T, Ju Q, Lin J, Bierhaus A, Nawroth P, Hannak D, Neumaier M, Bergfeld R, Giardino I, Brownlee M.

Nat Med. 2003 Mar;9(3):294-9. Epub 2003 Feb 18.PMID: 12592403 [PubMed - indexed for MEDLINE]Related articles

High-dose thiamine therapy counters dyslipidemia and advanced glycation of plasma protein in streptozotocin-induced diabetic rats.

Karachalias N, Babaei-Jadidi R, Kupich C, Ahmed N, Thornalley PJ.

Ann N Y Acad Sci. 2005 Jun;1043:777-83.PMID: 16037305 [PubMed - indexed for MEDLINE]Related articles

High-dose thiamine therapy counters dyslipidaemia in streptozotocin-induced diabetic rats.

Babaei-Jadidi R, Karachalias N, Kupich C, Ahmed N, Thornalley PJ.

Diabetologia. 2004 Dec;47(12):2235-46. Epub 2004 Dec 11.PMID: 15662560 [PubMed - indexed for MEDLINE]Related articles

Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.

Thornalley PJ, Jahan I, Ng R.

J Biochem. 2001 Apr;129(4):543-9.PMID: 11275553 [PubMed - indexed for MEDLINE]Related articles

High-dose benfotiamine rescues cardiomyocyte contractile dysfunction in streptozotocin-induced diabetes mellitus.

Ceylan-Isik AF, Wu S, Li Q, Li SY, Ren J.

J Appl Physiol. 2006 Jan;100(1):150-6. Epub 2005 Sep 15.PMID: 16166234 [PubMed - indexed for MEDLINE]Related articlesFree article

Benfotiamine accelerates the healing of ischaemic diabetic limbs in mice through protein kinase B/Akt-mediated potentiation of angiogenesis and inhibition of apoptosis.

Gadau S, Emanueli C, Van Linthout S, Graiani G, Todaro M, Meloni M, Campesi I, Invernici G, Spillmann F, Ward K, Madeddu P.

Diabetologia. 2006 Feb;49(2):405-20. Epub 2006 Jan 17.PMID: 16416271 [PubMed - indexed for MEDLINE]Related articles

Benfotiamine exhibits direct antioxidative capacity and prevents induction of DNA damage in vitro.

Schmid U, Stopper H, Heidland A, Schupp N.

Diabetes Metab Res Rev. 2008 Jul-Aug;24(5):371-7.PMID: 18384109 [PubMed - indexed for MEDLINE]Related articles

Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats.

Stracke H, Hammes HP, Werkmann D, Mavrakis K, Bitsch I, Netzel M, Geyer J, Köpcke W, Sauerland C, Bretzel RG, Federlin KF.

Exp Clin Endocrinol Diabetes. 2001;109(6):330-6.PMID: 11571671 [PubMed - indexed for MEDLINE]Related articles

Benfotiamine alleviates diabetes-induced cerebral oxidative damage independent of advanced glycation end-product, tissue factor and TNF-alpha.

Wu S, Ren J.

Neurosci Lett. 2006 Feb 13;394(2):158-62. Epub 2005 Oct 28.PMID: 16260089 [PubMed - indexed for MEDLINE]Related articles

High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine.

Frank T, Bitsch R, Maiwald J, Stein G.

Eur J Clin Pharmacol. 2000 Jun;56(3):251-7.PMID: 10952481 [PubMed - indexed for MEDLINE]Related articles

Thiamine and benfotiamine prevent increased apoptosis in endothelial cells and pericytes cultured in high glucose.

Beltramo E, Berrone E, Buttiglieri S, Porta M.

Diabetes Metab Res Rev. 2004 Jul-Aug;20(4):330-6.PMID: 15250036 [PubMed - indexed for MEDLINE]Related articles

Vitamin B1 blocks damage caused by hyperglycemia.

Obrenovich ME, Monnier VM.

Sci Aging Knowledge Environ. 2003 Mar 12;2003(10):PE6.PMID: 12844520 [PubMed - indexed for MEDLINE]Related articles

Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a type 1 diabetic nephropathy model.

Ichinose K, Maeshima Y, Yamamoto Y, Kitayama H, Takazawa Y, Hirokoshi K, Sugiyama H, Yamasaki Y, Eguchi K, Makino H.

Diabetes. 2005 Oct;54(10):2891-903. Erratum in: Diabetes. 2006 Sep;55(9):2665. PMID: 16186390 [PubMed - indexed for MEDLINE]Related articlesFree article

Renal p38 MAP kinase activity in experimental diabetes.

Komers R, Lindsley JN, Oyama TT, Cohen DM, Anderson S.

Lab Invest. 2007 Jun;87(6):548-58. Epub 2007 Apr 2.PMID: 17401436 [PubMed - indexed for MEDLINE]Related articlesFree article

Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose.

Pomero F, Molinar Min A, La Selva M, Allione A, Molinatti GM, Porta M.

Acta Diabetol. 2001;38(3):135-8.PMID: 11827434 [PubMed - indexed for MEDLINE]Related articles

Effects of thiamine and benfotiamine on intracellular glucose metabolism and relevance in the prevention of diabetic complications.

Beltramo E, Berrone E, Tarallo S, Porta M.

Acta Diabetol. 2008 Sep;45(3):131-41. Epub 2008 Jun 26. Review.PMID: 18581039 [PubMed - indexed for MEDLINE]Related articles

Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats.

Karachalias N, Babaei-Jadidi R, Ahmed N, Thornalley PJ.

Biochem Soc Trans. 2003 Dec;31(Pt 6):1423-5. Review.PMID: 14641079 [PubMed - indexed for MEDLINE]Related articles