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Diabetogenic potential of human pathogens uncovered in experimentally permissive beta-cells.
Flodström M, Tsai D, Fine C, Maday A, Sarvetnick N.
Diabetes. 2003 Aug;52(8):2025-34.PMID: 12882919 [PubMed - indexed for MEDLINE]Related articlesFree article
Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse.
Flodström-Tullberg M, Yadav D, Hägerkvist R, Tsai D, Secrest P, Stotland A, Sarvetnick N.
Diabetes. 2003 Nov;52(11):2696-700.PMID: 14578288 [PubMed - indexed for MEDLINE]Related articlesFree article
Target cell defense prevents the development of diabetes after viral infection.
Flodström M, Maday A, Balakrishna D, Cleary MM, Yoshimura A, Sarvetnick N.
Nat Immunol. 2002 Apr;3(4):373-82. Epub 2002 Mar 4.PMID: 11919579 [PubMed - indexed for MEDLINE]Related articles
Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.
Chong MM, Chen Y, Darwiche R, Dudek NL, Irawaty W, Santamaria P, Allison J, Kay TW, Thomas HE.
J Immunol. 2004 May 1;172(9):5714-21.PMID: 15100317 [PubMed - indexed for MEDLINE]Related articlesFree article
Differences in suppressor of cytokine signaling-1 (SOCS-1) expressing islet allograft destruction in normal BALB/c and spontaneously-diabetic NOD recipient mice.
Solomon M, Flodström-Tullberg M, Sarvetnick N.
Transplantation. 2005 May 15;79(9):1104-9.PMID: 15880051 [PubMed - indexed for MEDLINE]Related articles
Pathological changes in the islet milieu precede infiltration of islets and destruction of beta-cells by autoreactive lymphocytes in a transgenic model of virus-induced IDDM.
von Herrath M, Holz A.
J Autoimmun. 1997 Jun;10(3):231-8.PMID: 9218748 [PubMed - indexed for MEDLINE]Related articles
SOCS-1 protects from virally-induced CD8 T cell mediated type 1 diabetes.
Barral AM, Thomas HE, Ling EM, Darwiche R, Rodrigo E, Christen U, Ejrnaes M, Wolfe T, Kay TW, von Herrath MG.
J Autoimmun. 2006 Nov;27(3):166-73. Epub 2006 Oct 10.PMID: 17045460 [PubMed - indexed for MEDLINE]Related articles
Neither B lymphocytes nor antibodies directed against self antigens of the islets of Langerhans are required for development of virus-induced autoimmune diabetes.
Holz A, Dyrberg T, Hagopian W, Homann D, von Herrath M, Oldstone MB.
J Immunol. 2000 Nov 15;165(10):5945-53.PMID: 11067957 [PubMed - indexed for MEDLINE]Related articlesFree article
Regulatory T-cells protect from type 1 diabetes after induction by coxsackievirus infection in the context of transforming growth factor-beta.
Richer MJ, Straka N, Fang D, Shanina I, Horwitz MS.
Diabetes. 2008 May;57(5):1302-11. Epub 2008 Feb 11.PMID: 18268045 [PubMed - indexed for MEDLINE]Related articlesFree article
Absence of TNFRp55 influences virus-induced autoimmunity despite efficient lymphocytic infiltration.
McKall-Faienza KJ, Kawai K, Kündig TM, Odermatt B, Bachmann MF, Zakarian A, Mak TW, Ohashi PS.
Int Immunol. 1998 Apr;10(4):405-12.PMID: 9620596 [PubMed - indexed for MEDLINE]Related articlesFree article
Coxsackievirus B3 infection and type 1 diabetes development in NOD mice: insulitis determines susceptibility of pancreatic islets to virus infection.
Drescher KM, Kono K, Bopegamage S, Carson SD, Tracy S.
Virology. 2004 Nov 24;329(2):381-94.PMID: 15518817 [PubMed - indexed for MEDLINE]Related articles
Fas is detectable on beta cells in accelerated, but not spontaneous, diabetes in nonobese diabetic mice.
Darwiche R, Chong MM, Santamaria P, Thomas HE, Kay TW.
J Immunol. 2003 Jun 15;170(12):6292-7.PMID: 12794162 [PubMed - indexed for MEDLINE]Related articlesFree article
RNase L and double-stranded RNA-dependent protein kinase exert complementary roles in islet cell defense during coxsackievirus infection.
Flodström-Tullberg M, Hultcrantz M, Stotland A, Maday A, Tsai D, Fine C, Williams B, Silverman R, Sarvetnick N.
J Immunol. 2005 Feb 1;174(3):1171-7.PMID: 15661870 [PubMed - indexed for MEDLINE]Related articlesFree article
Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus.
von Herrath MG, Oldstone MB.
J Exp Med. 1997 Feb 3;185(3):531-9.PMID: 9053453 [PubMed - indexed for MEDLINE]Related articlesFree article
Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.
Serreze DV, Johnson EA, Chapman HD, Graser RT, Marron MP, DiLorenzo TP, Silveira P, Yoshimura Y, Nathenson SG, Joyce S.
Diabetes. 2001 Sep;50(9):1992-2000.PMID: 11522664 [PubMed - indexed for MEDLINE]Related articlesFree article
Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice.
von Herrath MG, Dyrberg T, Oldstone MB.
J Clin Invest. 1996 Sep 15;98(6):1324-31.PMID: 8823297 [PubMed - indexed for MEDLINE]Related articlesFree article
Type 1 diabetes: virus infection or autoimmune disease?
Fairweather D, Rose NR.
Nat Immunol. 2002 Apr;3(4):338-40. No abstract available. PMID: 11919574 [PubMed - indexed for MEDLINE]Related articles
Diabetes acceleration or prevention by a coxsackievirus B4 infection: critical requirements for both interleukin-4 and gamma interferon.
Serreze DV, Wasserfall C, Ottendorfer EW, Stalvey M, Pierce MA, Gauntt C, O'Donnell B, Flanagan JB, Campbell-Thompson M, Ellis TM, Atkinson MA.
J Virol. 2005 Jan;79(2):1045-52.PMID: 15613333 [PubMed - indexed for MEDLINE]Related articlesFree article
Protection from type 1 diabetes in the face of high levels of activated autoaggressive lymphocytes in a viral transgenic mouse model crossed to the SV129 strain.
von Herrath MG, Wolfe T, Möhrle U, Coon B, Hughes A.
Diabetes. 2001 Dec;50(12):2700-8.PMID: 11723052 [PubMed - indexed for MEDLINE]Related articlesFree article
Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence.
Tracy S, Drescher KM, Chapman NM, Kim KS, Carson SD, Pirruccello S, Lane PH, Romero JR, Leser JS.
J Virol. 2002 Dec;76(23):12097-111.PMID: 12414951 [PubMed - indexed for MEDLINE]Related articlesFree article
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