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    Results: 1 to 20 of 151

    1.

    Free radicals and the pathogenesis of type 1 diabetes: beta-cell cytokine-mediated free radical generation via cyclooxygenase-2.

    Tabatabaie T, Vasquez-Weldon A, Moore DR, Kotake Y.

    Diabetes. 2003 Aug;52(8):1994-9.PMID: 12882915 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Role of cyclooxygenase-2 in cytokine-induced beta-cell dysfunction and damage by isolated rat and human islets.

    Heitmeier MR, Kelly CB, Ensor NJ, Gibson KA, Mullis KG, Corbett JA, Maziasz TJ.

    J Biol Chem. 2004 Dec 17;279(51):53145-51. Epub 2004 Oct 7.PMID: 15471850 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress.

    Kharroubi I, Ladrière L, Cardozo AK, Dogusan Z, Cnop M, Eizirik DL.

    Endocrinology. 2004 Nov;145(11):5087-96. Epub 2004 Aug 5.PMID: 15297438 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Direct administration of interleukin-1 and interferon-gamma to rat pancreas leads to the in vivo production of nitric oxide and expression of inducible nitric oxide synthase and inducible cyclooxygenase.

    Tabatabaie T, Vasquez AM, Moore DR, Floyd RA, Kotake Y.

    Pancreas. 2001 Oct;23(3):316-22.PMID: 11590329 [PubMed - indexed for MEDLINE]Related articles

    5.

    Inhibition of interleukin-1beta-induced COX-2 and EP3 gene expression by sodium salicylate enhances pancreatic islet beta-cell function.

    Tran PO, Gleason CE, Robertson RP.

    Diabetes. 2002 Jun;51(6):1772-8.PMID: 12031964 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Synergistic anti-inflammatory activity of omega-3 lipid and rofecoxib pretreatment on macrophage proinflammatory cytokine production occurs via divergent NF-kappaB activation.

    Babcock TA, Helton WS, Anwar KN, Zhao YY, Espat NJ.

    JPEN J Parenter Enteral Nutr. 2004 Jul-Aug;28(4):232-9; discussion 239-40.PMID: 15291404 [PubMed - indexed for MEDLINE]Related articles

    7.

    Nf-kappab activation is associated with free radical generation and endotoxemia and precedes pathological liver injury in experimental alcoholic liver disease.

    Jokelainen K, Reinke LA, Nanji AA.

    Cytokine. 2001 Oct 7;16(1):36-9.PMID: 11669585 [PubMed - indexed for MEDLINE]Related articles

    8.

    Arachidonic acid-induced carbon-centered radicals and phospholipid peroxidation in cyclo-oxygenase-2-transfected PC12 cells.

    Jiang J, Borisenko GG, Osipov A, Martin I, Chen R, Shvedova AA, Sorokin A, Tyurina YY, Potapovich A, Tyurin VA, Graham SH, Kagan VE.

    J Neurochem. 2004 Sep;90(5):1036-49.PMID: 15312159 [PubMed - indexed for MEDLINE]Related articles

    9.

    Destruction of rat pancreatic islet beta-cells by cytokines involves the production of cytotoxic aldehydes.

    Suarez-Pinzon WL, Strynadka K, Rabinovitch A.

    Endocrinology. 1996 Dec;137(12):5290-6.PMID: 8940348 [PubMed - indexed for MEDLINE]Related articles

    10.

    Mechanisms underlying resistance of pancreatic islets from ALR/Lt mice to cytokine-induced destruction.

    Mathews CE, Suarez-Pinzon WL, Baust JJ, Strynadka K, Leiter EH, Rabinovitch A.

    J Immunol. 2005 Jul 15;175(2):1248-56.PMID: 16002729 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Free radical-triggered hepatic injury of experimental obstructive jaundice of rats involves overproduction of proinflammatory cytokines and enhanced activation of nuclear factor kappaB.

    Liu TZ, Lee KT, Chern CL, Cheng JT, Stern A, Tsai LY.

    Ann Clin Lab Sci. 2001 Oct;31(4):383-90.PMID: 11688850 [PubMed - indexed for MEDLINE]Related articles

    12.

    Lipid a radiosensitizes hypoxic EMT-6 tumor cells: role of the NF-kappaB signaling pathway.

    de Ridder M, Verovski VN, Van den Berge DL, Sermeus AB, Monsaert C, Wauters N, Storme GA.

    Int J Radiat Oncol Biol Phys. 2003 Nov 1;57(3):779-86.PMID: 14529784 [PubMed - indexed for MEDLINE]Related articles

    13.

    Tumor necrosis factor alpha and interleukin-1beta stimulate the expression of cyclooxygenase II but do not alter prostaglandin E2 receptor mRNA levels in cultured dorsal root ganglia cells.

    Fehrenbacher JC, Burkey TH, Nicol GD, Vasko MR.

    Pain. 2005 Jan;113(1-2):113-22.PMID: 15621371 [PubMed - indexed for MEDLINE]Related articles

    14.

    An in vitro screening assay for inhibitors of proinflammatory mediators in herbal extracts using human synoviocyte cultures.

    Frondoza CG, Sohrabi A, Polotsky A, Phan PV, Hungerford DS, Lindmark L.

    In Vitro Cell Dev Biol Anim. 2004 Mar-Apr;40(3-4):95-101.PMID: 15311968 [PubMed - indexed for MEDLINE]Related articles

    15.

    Inhibitory effects of epicatechin on interleukin-1beta-induced inducible nitric oxide synthase expression in RINm5F cells and rat pancreatic islets by down-regulation of NF-kappaB activation.

    Kim MJ, Ryu GR, Kang JH, Sim SS, Min DS, Rhie DJ, Yoon SH, Hahn SJ, Jeong IK, Hong KJ, Kim MS, Jo YH.

    Biochem Pharmacol. 2004 Nov 1;68(9):1775-85.PMID: 15450943 [PubMed - indexed for MEDLINE]Related articles

    16.

    Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition.

    Totzke G, Schulze-Osthoff K, Jänicke RU.

    Oncogene. 2003 Sep 11;22(39):8021-30.PMID: 12970750 [PubMed - indexed for MEDLINE]Related articles

    17.

    Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity.

    Biswas SK, McClure D, Jimenez LA, Megson IL, Rahman I.

    Antioxid Redox Signal. 2005 Jan-Feb;7(1-2):32-41.PMID: 15650394 [PubMed - indexed for MEDLINE]Related articles

    18.

    Activation of peroxisome proliferator-activated receptor-gamma protects pancreatic beta-cells from cytokine-induced cytotoxicity via NF kappaB pathway.

    Kim EK, Kwon KB, Koo BS, Han MJ, Song MY, Song EK, Han MK, Park JW, Ryu DG, Park BH.

    Int J Biochem Cell Biol. 2007;39(6):1260-75. Epub 2007 Apr 19.PMID: 17521952 [PubMed - indexed for MEDLINE]Related articles

    19.

    Oxygen free radical scavengers protect rat islet cells from damage by cytokines.

    Sumoski W, Baquerizo H, Rabinovitch A.

    Diabetologia. 1989 Nov;32(11):792-6.PMID: 2480259 [PubMed - indexed for MEDLINE]Related articles

    20.

    Cytotoxic effects of cytokines on rat islets: evidence for involvement of free radicals and lipid peroxidation.

    Rabinovitch A, Suarez WL, Thomas PD, Strynadka K, Simpson I.

    Diabetologia. 1992 May;35(5):409-13.PMID: 1521720 [PubMed - indexed for MEDLINE]Related articles

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