PubMed

HIV protease inhibitors acutely impair glucose-stimulated insulin release.

Koster JC, Remedi MS, Qiu H, Nichols CG, Hruz PW.

Diabetes. 2003 Jul;52(7):1695-700.PMID: 12829635 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term effects of HIV-1 protease inhibitors on insulin secretion and insulin signaling in INS-1 beta cells.

Schütt M, Zhou J, Meier M, Klein HH.

J Endocrinol. 2004 Dec;183(3):445-54.PMID: 15590971 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct interference of HIV protease inhibitors with pancreatic beta-cell function.

Düfer M, Neye Y, Krippeit-Drews P, Drews G.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Jun;369(6):583-90. Epub 2004 May 7.PMID: 15197535 [PubMed - indexed for MEDLINE]Related articles

Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets.

Ishihara H, Asano T, Tsukuda K, Katagiri H, Inukai K, Anai M, Kikuchi M, Yazaki Y, Miyazaki JI, Oka Y.

Diabetologia. 1993 Nov;36(11):1139-45.PMID: 8270128 [PubMed - indexed for MEDLINE]Related articles

[Effects of various HIV protease inhibitors on function of rat insulinoma cells]

Zhou JQ, Li WP, Xiang Z, Schutt M.

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2006 May;35(3):251-4. Chinese. PMID: 16764025 [PubMed - indexed for MEDLINE]Related articles

Indinavir induces acute and reversible peripheral insulin resistance in rats.

Hruz PW, Murata H, Qiu H, Mueckler M.

Diabetes. 2002 Apr;51(4):937-42.PMID: 11916910 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.

Johnson D, Shepherd RM, Gill D, Gorman T, Smith DM, Dunne MJ.

Diabetes. 2007 Jun;56(6):1694-702. Epub 2007 Mar 14.PMID: 17360975 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effect of HIV protease inhibitors on adipogenesis: intracellular ritonavir is not sufficient to inhibit differentiation.

Vernochet C, Azoulay S, Duval D, Guedj R, Ailhaud G, Dani C.

AIDS. 2003 Oct 17;17(15):2177-80.PMID: 14523274 [PubMed - indexed for MEDLINE]Related articles

A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity.

Hertel J, Struthers H, Horj CB, Hruz PW.

J Biol Chem. 2004 Dec 31;279(53):55147-52. Epub 2004 Oct 20.PMID: 15496402 [PubMed - indexed for MEDLINE]Related articlesFree article

HIV protease inhibitors: suppression of insulin secretion by inhibition of voltage-dependent K+ currents and anion currents.

Neye Y, Düfer M, Drews G, Krippeit-Drews P.

J Pharmacol Exp Ther. 2006 Jan;316(1):106-12. Epub 2005 Sep 14.PMID: 16162820 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct comparison of the acute in vivo effects of HIV protease inhibitors on peripheral glucose disposal.

Yan Q, Hruz PW.

J Acquir Immune Defic Syndr. 2005 Dec 1;40(4):398-403.PMID: 16280693 [PubMed - indexed for MEDLINE]Related articlesFree article

HIV protease inhibitors block adipogenesis and increase lipolysis in vitro.

Lenhard JM, Furfine ES, Jain RG, Ittoop O, Orband-Miller LA, Blanchard SG, Paulik MA, Weiel JE.

Antiviral Res. 2000 Aug;47(2):121-9.PMID: 10996400 [PubMed - indexed for MEDLINE]Related articles

Indinavir acutely inhibits insulin-stimulated glucose disposal in humans: a randomized, placebo-controlled study.

Noor MA, Seneviratne T, Aweeka FT, Lo JC, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C.

AIDS. 2002 Mar 29;16(5):F1-8.PMID: 11964551 [PubMed - indexed for MEDLINE]Related articles

Inhibition of glucose-stimulated insulin release from beta TC3 cells and rodent islets by an analog of FK506.

Herold KC, Nagamatsu S, Buse JB, Kulsakdinun P, Steiner DF.

Transplantation. 1993 Jan;55(1):186-92.PMID: 7678356 [PubMed - indexed for MEDLINE]Related articles

The long-term effects of anti-retroviral protease inhibitors on sugar transport in L6 cells.

Germinario RJ, Colby-Germinario SP, Cammalleri C, Wainberg MA.

J Endocrinol. 2003 Sep;178(3):449-56.PMID: 12967347 [PubMed - indexed for MEDLINE]Related articlesFree article

ACTH stimulates insulin secretion from MIN6 cells and primary mouse and human islets of Langerhans.

Al-Majed HT, Jones PM, Persaud SJ, Sugden D, Huang GC, Amiel S, Whitehouse BJ.

J Endocrinol. 2004 Jan;180(1):155-66.PMID: 14709154 [PubMed - indexed for MEDLINE]Related articlesFree article

Synergistic antiadipogenic effects of HIV type 1 protease inhibitors with tumor necrosis factor alpha: suppression of extracellular insulin action mediated by extracellular matrix-degrading proteases.

Mondal D, Larussa VF, Agrawal KC.

AIDS Res Hum Retroviruses. 2001 Nov 20;17(17):1569-84.PMID: 11779345 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance in HIV protease inhibitor-associated diabetes.

Yarasheski KE, Tebas P, Sigmund C, Dagogo-Jack S, Bohrer A, Turk J, Halban PA, Cryer PE, Powderly WG.

J Acquir Immune Defic Syndr. 1999 Jul 1;21(3):209-16.PMID: 10421244 [PubMed - indexed for MEDLINE]Related articles

Glucose uptake, utilization, and signaling in GLUT2-null islets.

Guillam MT, Dupraz P, Thorens B.

Diabetes. 2000 Sep;49(9):1485-91.PMID: 10969832 [PubMed - indexed for MEDLINE]Related articlesFree article

Interactions of HIV protease inhibitors with a human organic cation transporter in a mammalian expression system.

Zhang L, Gorset W, Washington CB, Blaschke TF, Kroetz DL, Giacomini KM.

Drug Metab Dispos. 2000 Mar;28(3):329-34.PMID: 10681378 [PubMed - indexed for MEDLINE]Related articlesFree article