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Poly (ADP-ribose) polymerase inhibition prevents spontaneous and recurrent autoimmune diabetes in NOD mice by inducing apoptosis of islet-infiltrating leukocytes.
Suarez-Pinzon WL, Mabley JG, Power R, Szabó C, Rabinovitch A.
Diabetes. 2003 Jul;52(7):1683-8.PMID: 12829633 [PubMed - indexed for MEDLINE]Related articlesFree article
Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice.
Rabinovitch A, Suarez-Pinzon WL, Shapiro AM, Rajotte RV, Power R.
Diabetes. 2002 Mar;51(3):638-45.PMID: 11872661 [PubMed - indexed for MEDLINE]Related articlesFree article
Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction.
Suarez-Pinzon W, Rajotte RV, Mosmann TR, Rabinovitch A.
Diabetes. 1996 Oct;45(10):1350-7.PMID: 8826970 [PubMed - indexed for MEDLINE]Related articles
Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets.
Suarez-Pinzon W, Sorensen O, Bleackley RC, Elliott JF, Rajotte RV, Rabinovitch A.
Diabetes. 1999 Jan;48(1):21-8.PMID: 9892218 [PubMed - indexed for MEDLINE]Related articlesFree article
IFN-gamma gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice.
Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Bleackley RC, Power RF.
J Immunol. 1995 May 1;154(9):4874-82.PMID: 7722337 [PubMed - indexed for MEDLINE]Related articles
Combined therapy with interleukin-4 and interleukin-10 inhibits autoimmune diabetes recurrence in syngeneic islet-transplanted nonobese diabetic mice. Analysis of cytokine mRNA expression in the graft.
Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Bleackley RC, Power RF, Rajotte RV.
Transplantation. 1995 Aug 27;60(4):368-74.PMID: 7652767 [PubMed - indexed for MEDLINE]Related articles
Interleukin 12 mRNA expression in islets correlates with beta-cell destruction in NOD mice.
Rabinovitch A, Suarez-Pinzon WL, Sorensen O.
J Autoimmun. 1996 Oct;9(5):645-51.PMID: 8933280 [PubMed - indexed for MEDLINE]Related articles
Gene transfection and expression of transforming growth factor-beta1 in nonobese diabetic mouse islets protects beta-cells in syngeneic islet grafts from autoimmune destruction.
Suarez-Pinzon WL, Marcoux Y, Ghahary A, Rabinovitch A.
Cell Transplant. 2002;11(6):519-28.PMID: 12428741 [PubMed - indexed for MEDLINE]Related articles
Analysis of cytokine mRNA expression in syngeneic islet grafts of NOD mice: interleukin 2 and interferon gamma mRNA expression correlate with graft rejection and interleukin 10 with graft survival.
Rabinovitch A, Sorensen O, Suarez-Pinzon WL, Power RF, Rajotte RV, Bleackley RC.
Diabetologia. 1994 Aug;37(8):833-7.PMID: 7988786 [PubMed - indexed for MEDLINE]Related articles
Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice.
Shapiro AM, Suarez-Pinzon WL, Power R, Rabinovitch A.
Diabetologia. 2002 Feb;45(2):224-30.PMID: 11935154 [PubMed - indexed for MEDLINE]Related articles
Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes.
Mabley JG, Suarez-Pinzon WL, Haskó G, Salzman AL, Rabinovitch A, Kun E, Szabó C.
Br J Pharmacol. 2001 Jul;133(6):909-19.PMID: 11454665 [PubMed - indexed for MEDLINE]Related articlesFree article
TNF-alpha down-regulates type 1 cytokines and prolongs survival of syngeneic islet grafts in nonobese diabetic mice.
Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Rajotte RV, Power RF.
J Immunol. 1997 Dec 15;159(12):6298-303.PMID: 9550435 [PubMed - indexed for MEDLINE]Related articles
Fas ligand-mediated mechanisms are involved in autoimmune destruction of islet beta cells in non-obese diabetic mice.
Suarez-Pinzon WL, Power RF, Rabinovitch A.
Diabetologia. 2000 Sep;43(9):1149-56.PMID: 11043861 [PubMed - indexed for MEDLINE]Related articles
Combination therapy with cyclosporine and interleukin-4 or interleukin-10 prolongs survival of synergeneic pancreatic islet grafts in nonobese diabetic mice: islet graft survival does not correlate with mRNA levels of type 1 or type 2 cytokines, or transforming growth factor-beta in the islet grafts.
Transplantation. 1997 Dec 15;64(11):1525-31.PMID: 9415551 [PubMed - indexed for MEDLINE]Related articles
The novel anti-inflammatory agent lisofylline prevents autoimmune diabetic recurrence after islet transplantation.
Yang Z, Chen M, Ellett JD, Fialkow LB, Carter JD, Nadler JL.
Transplantation. 2004 Jan 15;77(1):55-60.PMID: 14724435 [PubMed - indexed for MEDLINE]Related articles
Intrathymic islet cell transplantation reduces beta-cell autoimmunity and prevents diabetes in NOD/Lt mice.
Gerling IC, Serreze DV, Christianson SW, Leiter EH.
Diabetes. 1992 Dec;41(12):1672-6.PMID: 1446808 [PubMed - indexed for MEDLINE]Related articles
IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death.
Suk K, Kim S, Kim YH, Kim KA, Chang I, Yagita H, Shong M, Lee MS.
J Immunol. 2001 Apr 1;166(7):4481-9.PMID: 11254704 [PubMed - indexed for MEDLINE]Related articlesFree article
[Inhibition of islet beta cell apoptosis and prevention diabetes by subcutaneous administration of insulin in NOD mice]
Jiang TJ, Zhou ZG, Su H.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2006 Aug;31(4):499-504. Chinese. PMID: 16951506 [PubMed - indexed for MEDLINE]Related articlesFree article
A new type of CD4+ suppressor T cell completely prevents spontaneous autoimmune diabetes and recurrent diabetes in syngeneic islet-transplanted NOD mice.
Han HS, Jun HS, Utsugi T, Yoon JW.
J Autoimmun. 1996 Jun;9(3):331-9.PMID: 8816968 [PubMed - indexed for MEDLINE]Related articles
Apoptosis and beta-cell destruction in pancreatic islets of NOD mice with spontaneous and cyclophosphamide-accelerated diabetes.
Augstein P, Elefanty AG, Allison J, Harrison LC.
Diabetologia. 1998 Nov;41(11):1381-8.PMID: 9833948 [PubMed - indexed for MEDLINE]Related articles
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