PubMed

Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity.

Stefan N, Kovacs P, Stumvoll M, Hanson RL, Lehn-Stefan A, Permana PA, Baier LJ, Tataranni PA, Silver K, Bogardus C.

Diabetes. 2003 Jun;52(6):1544-50.PMID: 12765968 [PubMed - indexed for MEDLINE]Related articlesFree article

Endogenous glucose production, insulin sensitivity, and insulin secretion in normal glucose-tolerant Pima Indians with low birth weight.

Stefan N, Weyer C, Levy-Marchal C, Stumvoll M, Knowler WC, Tataranni PA, Bogardus C, Pratley RE.

Metabolism. 2004 Jul;53(7):904-11.PMID: 15254885 [PubMed - indexed for MEDLINE]Related articles

Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Mexican Americans with Type 2 diabetes mellitus.

Celi FS, Negri C, Tanner K, Raben N, De Pablo F, Rovira A, Pallardo LF, Martin-Vaquero P, Stern MP, Mitchell BD, Shuldiner AR.

Diabetes Metab Res Rev. 2000 Sep-Oct;16(5):370-7.PMID: 11025561 [PubMed - indexed for MEDLINE]Related articles

Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome.

Ehrmann DA, Tang X, Yoshiuchi I, Cox NJ, Bell GI.

J Clin Endocrinol Metab. 2002 Sep;87(9):4297-300.PMID: 12213887 [PubMed - indexed for MEDLINE]Related articlesFree article

The G972R variant of the insulin receptor substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance.

Baroni MG, Arca M, Sentinelli F, Buzzetti R, Capici F, Lovari S, Vitale M, Romeo S, Di Mario U.

Diabetologia. 2001 Mar;44(3):367-72.PMID: 11317670 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms of the insulin receptor substrate-2 in patients with type 2 diabetes.

D'Alfonso R, Marini MA, Frittitta L, Sorge R, Frontoni S, Porzio O, Mariani LM, Lauro D, Gambardella S, Trischitta V, Federici M, Lauro R, Sesti G.

J Clin Endocrinol Metab. 2003 Jan;88(1):317-22.PMID: 12519871 [PubMed - indexed for MEDLINE]Related articlesFree article

Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity.

Almind K, Frederiksen SK, Bernal D, Hansen T, Ambye L, Urhammer S, Ekstrøm CT, Berglund L, Reneland R, Lithell H, White MF, Van Obberghen E, Pedersen O.

Diabetologia. 1999 Oct;42(10):1244-9.PMID: 10525667 [PubMed - indexed for MEDLINE]Related articles

Relationship of hepatic and peripheral insulin resistance with plasminogen activator inhibitor-1 in Pima Indians.

Nagi DK, Tracy R, Pratley R.

Metabolism. 1996 Oct;45(10):1243-7.PMID: 8843179 [PubMed - indexed for MEDLINE]Related articles

Amino acid polymorphism Gly 972 Arg in IRS-1 is not associated to lower clamp-derived insulin sensitivity in young healthy first degree relatives of patients with type 2 diabetes.

Koch M, Rett K, Volk A, Maerker E, Haist K, Deninger M, Renn W, Häring HU.

Exp Clin Endocrinol Diabetes. 1999;107(5):318-22.PMID: 10482045 [PubMed - indexed for MEDLINE]Related articles

Insulin action and insulinemia are closely related to the fasting complement C3, but not acylation stimulating protein concentration.

Weyer C, Tataranni PA, Pratley RE.

Diabetes Care. 2000 Jun;23(6):779-85.PMID: 10840996 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the insulin receptor substrate-1 (IRS-1) gene and the insulin receptor substrate-2 (IRS-2) gene influence glucose homeostasis and body mass index in women with polycystic ovary syndrome and non-hyperandrogenic controls.

Villuendas G, Botella-Carretero JI, Roldán B, Sancho J, Escobar-Morreale HF, San Millán JL.

Hum Reprod. 2005 Nov;20(11):3184-91. Epub 2005 Jul 21.PMID: 16037106 [PubMed - indexed for MEDLINE]Related articlesFree article

New amino acid substitutions in the IRS-2 gene in Finnish and Chinese subjects with late-onset type 2 diabetes.

Wang H, Rissanen J, Miettinen R, Kärkkäinen P, Kekäläinen P, Kuusisto J, Mykkänen L, Karhapää P, Laakso M.

Diabetes. 2001 Aug;50(8):1949-51.PMID: 11473060 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated plasma nonesterified fatty acids are associated with deterioration of acute insulin response in IGT but not NGT.

Stefan N, Stumvoll M, Bogardus C, Tataranni PA.

Am J Physiol Endocrinol Metab. 2003 Jun;284(6):E1156-61. Epub 2003 Feb 11.PMID: 12582008 [PubMed - indexed for MEDLINE]Related articlesFree article

High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes.

Vozarova B, Stefan N, Lindsay RS, Saremi A, Pratley RE, Bogardus C, Tataranni PA.

Diabetes. 2002 Jun;51(6):1889-95.PMID: 12031978 [PubMed - indexed for MEDLINE]Related articlesFree article

High serum resistin is associated with an increase in adiposity but not a worsening of insulin resistance in Pima Indians.

Vozarova de Courten B, Degawa-Yamauchi M, Considine RV, Tataranni PA.

Diabetes. 2004 May;53(5):1279-84. Erratum in: Diabetes. 2004 Sep;53(9):2518. Volarova de Courten, B [corrected to Vozarova de Courten, B]. PMID: 15111497 [PubMed - indexed for MEDLINE]Related articlesFree article

The G1057D polymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian Indians.

Bodhini D, Radha V, Deepa R, Ghosh S, Majumder PP, Rao MR, Mohan V.

Int J Obes (Lond). 2007 Jan;31(1):97-102. Epub 2006 Apr 25.PMID: 16652127 [PubMed - indexed for MEDLINE]Related articles

Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts type II diabetes independent of insulin resistance.

Weyer C, Foley JE, Bogardus C, Tataranni PA, Pratley RE.

Diabetologia. 2000 Dec;43(12):1498-506.PMID: 11151758 [PubMed - indexed for MEDLINE]Related articles

The role of insulin receptor substrate-1 gene (IRS1) in type 2 diabetes in Pima Indians.

Kovacs P, Hanson RL, Lee YH, Yang X, Kobes S, Permana PA, Bogardus C, Baier LJ.

Diabetes. 2003 Dec;52(12):3005-9.PMID: 14633864 [PubMed - indexed for MEDLINE]Related articlesFree article

A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians.

Muller YL, Bogardus C, Pedersen O, Baier L.

Diabetes. 2003 Mar;52(3):895-8.PMID: 12606537 [PubMed - indexed for MEDLINE]Related articlesFree article

The G1057D polymorphism of IRS-2 gene is not associated with type 2 diabetes and obese patients among ethnic groups in Tunisian population.

Ouederni TB, Sanchez-Corona J, Flores Martinez SE, Ben Maiz H, Skhiri HA, Abid HK, Benammar-Elgaaied A.

Clin Biochem. 2009 Jul;42(10-11):1169-73. Epub 2009 Mar 28.PMID: 19332049 [PubMed - indexed for MEDLINE]Related articles