PubMed

Identification of interactive loci linked to insulin and leptin in mice with genetic insulin resistance.

Almind K, Kulkarni RN, Lannon SM, Kahn CR.

Diabetes. 2003 Jun;52(6):1535-43.PMID: 12765967 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice.

Kulkarni RN, Almind K, Goren HJ, Winnay JN, Ueki K, Okada T, Kahn CR.

Diabetes. 2003 Jun;52(6):1528-34.PMID: 12765966 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic modifiers of the insulin resistance phenotype in mice.

Kido Y, Philippe N, Schäffer AA, Accili D.

Diabetes. 2000 Apr;49(4):589-96.PMID: 10871196 [PubMed - indexed for MEDLINE]Related articlesFree article

Allelic variation on chromosome 5 controls beta-cell mass expansion during hyperglycemia in leptin receptor-deficient diabetes mice.

Luo N, Liu SM, Liu H, Li Q, Xu Q, Sun X, Davis B, Li J, Chua S Jr.

Endocrinology. 2006 May;147(5):2287-95. Epub 2006 Feb 16.PMID: 16484328 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice.

Almind K, Kahn CR.

Diabetes. 2004 Dec;53(12):3274-85.PMID: 15561960 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model.

Mehrabian M, Wen PZ, Fisler J, Davis RC, Lusis AJ.

J Clin Invest. 1998 Jun 1;101(11):2485-96.PMID: 9616220 [PubMed - indexed for MEDLINE]Related articlesFree article

A major locus for fasting insulin concentrations and insulin resistance on chromosome 6q with strong pleiotropic effects on obesity-related phenotypes in nondiabetic Mexican Americans.

Duggirala R, Blangero J, Almasy L, Arya R, Dyer TD, Williams KL, Leach RJ, O'Connell P, Stern MP.

Am J Hum Genet. 2001 May;68(5):1149-64. Epub 2001 Mar 29.PMID: 11283790 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic analysis of obese diabetes in the TSOD mouse.

Hirayama I, Yi Z, Izumi S, Arai I, Suzuki W, Nagamachi Y, Kuwano H, Takeuchi T, Izumi T.

Diabetes. 1999 May;48(5):1183-91.PMID: 10331427 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic modifiers interact with Cpe(fat) to affect body weight, adiposity, and hyperglycemia.

Collin GB, Maddatu TP, Sen S, Naggert JK.

Physiol Genomics. 2005 Jul 14;22(2):182-90. Epub 2005 May 3.PMID: 15870393 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of genetic background and ablation of insulin receptor substrate (IRS)-3 on IRS-2 knock-out mice.

Terauchi Y, Matsui J, Suzuki R, Kubota N, Komeda K, Aizawa S, Eto K, Kimura S, Nagai R, Tobe K, Lienhard GE, Kadowaki T.

J Biol Chem. 2003 Apr 18;278(16):14284-90. Epub 2002 Dec 18.PMID: 12493745 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic linkage of hyperglycemia, body weight and serum amyloid-P in an intercross between C57BL/6 and C3H apolipoprotein E-deficient mice.

Su Z, Li Y, James JC, Matsumoto AH, Helm GA, Lusis AJ, Shi W.

Hum Mol Genet. 2006 May 15;15(10):1650-8. Epub 2006 Apr 4.PMID: 16595606 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of Nob3, a major quantitative trait locus for obesity and hyperglycemia on mouse chromosome 1.

Vogel H, Nestler M, Rüschendorf F, Block MD, Tischer S, Kluge R, Schürmann A, Joost HG, Scherneck S.

Physiol Genomics. 2009 Jul 9;38(2):226-32. Epub 2009 May 26.PMID: 19470805 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles.

Brüning JC, Winnay J, Bonner-Weir S, Taylor SI, Accili D, Kahn CR.

Cell. 1997 Feb 21;88(4):561-72.PMID: 9038347 [PubMed - indexed for MEDLINE]Related articles

Type 2 diabetes mouse model TallyHo carries an obesity gene on chromosome 6 that exaggerates dietary obesity.

Kim JH, Stewart TP, Zhang W, Kim HY, Nishina PM, Naggert JK.

Physiol Genomics. 2005 Jul 14;22(2):171-81. Epub 2005 May 3.PMID: 15870394 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci.

Stoehr JP, Nadler ST, Schueler KL, Rabaglia ME, Yandell BS, Metz SA, Attie AD.

Diabetes. 2000 Nov;49(11):1946-54.PMID: 11078464 [PubMed - indexed for MEDLINE]Related articlesFree article

Gender-influenced obesity QTLs identified in a cross involving the KK type II diabetes-prone mouse strain.

Taylor BA, Tarantino LM, Phillips SJ.

Mamm Genome. 1999 Oct;10(10):963-8.PMID: 10501964 [PubMed - indexed for MEDLINE]Related articles

Evidence for a circulating islet cell growth factor in insulin-resistant states.

Flier SN, Kulkarni RN, Kahn CR.

Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7475-80. Epub 2001 Jun 12.PMID: 11404474 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of compensatory beta-cell response in mice with combined mutations of Insr and Irs2.

Kim JJ, Kido Y, Scherer PE, White MF, Accili D.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1694-701. Epub 2007 Feb 13.PMID: 17299086 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait locus mapping of genetic modifiers of metabolic syndrome and atherosclerosis in low-density lipoprotein receptor-deficient mice: identification of a locus for metabolic syndrome and increased atherosclerosis on chromosome 4.

Seidelmann SB, De Luca C, Leibel RL, Breslow JL, Tall AR, Welch CL.

Arterioscler Thromb Vasc Biol. 2005 Jan;25(1):204-10. Epub 2004 Oct 28.PMID: 15514201 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein-tyrosine phosphatase 1B deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance.

Xue B, Kim YB, Lee A, Toschi E, Bonner-Weir S, Kahn CR, Neel BG, Kahn BB.

J Biol Chem. 2007 Aug 17;282(33):23829-40. Epub 2007 Jun 1.PMID: 17545163 [PubMed - indexed for MEDLINE]Related articlesFree article