PubMed

The degree of phylogenetic disparity of islet grafts dictates the reliance on indirect CD4 T-cell antigen recognition for rejection.

Rayat GR, Johnson ZA, Beilke JN, Korbutt GS, Rajotte RV, Gill RG.

Diabetes. 2003 Jun;52(6):1433-40.PMID: 12765954 [PubMed - indexed for MEDLINE]Related articlesFree article

Rejection of porcine islet xenografts mediated by CD4+ T cells activated through the indirect antigen recognition pathway.

Olack BJ, Jaramillo A, Benshoff ND, Kaleem Z, Swanson CJ, Lowell JA, Mohanakumar T.

Xenotransplantation. 2002 Nov;9(6):393-401.PMID: 12371935 [PubMed - indexed for MEDLINE]Related articles

MHC-mismatched islet allografts are vulnerable to autoimmune recognition in vivo.

Kupfer TM, Crawford ML, Pham K, Gill RG.

J Immunol. 2005 Aug 15;175(4):2309-16.PMID: 16081800 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute rejection of orthotopic corneal xenografts in mice depends on CD4(+) T cells and self-antigen-presenting cells.

Tanaka K, Sonoda K, Streilein JW.

Invest Ophthalmol Vis Sci. 2001 Nov;42(12):2878-84.PMID: 11687532 [PubMed - indexed for MEDLINE]Related articlesFree article

Prolonged survival of fetal pig islet xenografts in mice lacking the capacity for an indirect response.

Koulmanda M, Laufer TM, Auchincloss H Jr, Smith RN.

Xenotransplantation. 2004 Nov;11(6):525-30.PMID: 15479462 [PubMed - indexed for MEDLINE]Related articles

CD4 T cell-mediated cardiac allograft rejection requires donor but not host MHC class II.

Pietra BA, Wiseman A, Bolwerk A, Rizeq M, Gill RG.

J Clin Invest. 2000 Oct;106(8):1003-10.PMID: 11032860 [PubMed - indexed for MEDLINE]Related articlesFree article

Differences in the contribution of CD4+ T cells to proislet and islet allograft rejection correlate with constitutive class II MHC alloantigen expression.

Simeonovic CJ, Brown DJ, Townsend MJ, Wilson JD.

Cell Transplant. 1996 Sep-Oct;5(5):525-41.PMID: 8889212 [PubMed - indexed for MEDLINE]Related articles

Natural killer T cell facilitated engraftment of rat skin but not islet xenografts in mice.

Gordon EJ, Kelkar V.

Xenotransplantation. 2009 May;16(3):135-44.PMID: 19566653 [PubMed - indexed for MEDLINE]Related articles

Genetically engineered grafts to study xenoimmunity: a role for indirect antigen presentation in the destruction of major histocompatibility complex antigen deficient xenografts.

Markmann JF, Campos L, Bhandoola A, Kim JI, Desai NM, Bassiri H, Claytor BR, Barker CF.

Surgery. 1994 Aug;116(2):242-8; discussion 248-9.PMID: 8047991 [PubMed - indexed for MEDLINE]Related articles

Intrathymic inoculation of donor antigen: an ineffective strategy for prolonging xenograft survival.

Tran HM, Patel A, Allen RD, O'Connell PJ.

Xenotransplantation. 1999 May;6(2):147-54.PMID: 10431792 [PubMed - indexed for MEDLINE]Related articles

Rat pancreatic islet and skin xenograft survival in CD4 and CD8 knockout mice.

Krieger NR, Ito H, Fathman CG.

J Autoimmun. 1997 Jun;10(3):309-15.PMID: 9218759 [PubMed - indexed for MEDLINE]Related articles

Regulatory T cells maintain peripheral tolerance to islet allografts induced by intrathymic injection of MHC class I allopeptides.

Saborio DV, Chowdhury NC, Jin MX, Chandraker A, Sayegh MH, Oluwole SF.

Cell Transplant. 1999 Jul-Aug;8(4):375-81.PMID: 10478717 [PubMed - indexed for MEDLINE]Related articles

A major role for host MHC class I antigen presentation for promoting islet allograft survival.

Beilke J, Johnson Z, Kuhl N, Gill RG.

Transplant Proc. 2004 May;36(4):1173-4.PMID: 15194406 [PubMed - indexed for MEDLINE]Related articles

In vitro xenorecognition of adult pig pancreatic islet cells by splenocytes from nonobese diabetic or non-diabetes-prone mice.

Rivereau AS, You S, Lalain S, Gouin E, Saï P.

Transplantation. 1998 Sep 15;66(5):633-8.PMID: 9753345 [PubMed - indexed for MEDLINE]Related articles

Roles of CD4+ and CD8+ cells in islet allo- and xeno-graft rejection.

Gotoh M, Monden M, Yamamoto H, Kawai M, Ichikawa T, Mori T, Uenaka A, Nakayama E.

Horm Metab Res Suppl. 1990;25:173-6.PMID: 1982441 [PubMed - indexed for MEDLINE]Related articles

The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice.

Auchincloss H Jr, Lee R, Shea S, Markowitz JS, Grusby MJ, Glimcher LH.

Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3373-7.PMID: 8475083 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct requirements for host CD80/CD86 costimulatory molecules in cardiac versus islet rejection.

Johnson Z, Beilke J, Pietra B, Kelly B, Gill RG.

Transplant Proc. 2004 May;36(4):1171-2.PMID: 15194405 [PubMed - indexed for MEDLINE]Related articles

Immunotherapy with nondepleting anti-CD4 monoclonal antibodies but not CD28 antagonists protects islet graft in spontaneously diabetic nod mice from autoimmune destruction and allogeneic and xenogeneic graft rejection.

Guo Z, Wu T, Kirchhof N, Mital D, Williams JW, Azuma M, Sutherland DE, Hering BJ.

Transplantation. 2001 Jun 15;71(11):1656-65.PMID: 11435979 [PubMed - indexed for MEDLINE]Related articles

Delayed rejection of fetal pig pancreas in CD4 cell deficient mice was correlated with residual helper activity.

Zhan Y, Corbett AJ, Brady JL, Sutherland RM, Lew AM.

Xenotransplantation. 2000 Nov;7(4):267-74.PMID: 11081761 [PubMed - indexed for MEDLINE]Related articles

The critical role of mouse CD4+ cells in the rejection of highly disparate xenogeneic pig thymus grafts.

Zhao Y, Swenson K, Wekerle T, Rodriguez-Barbosa JI, Arn JS, Sykes M.

Xenotransplantation. 2000 May;7(2):129-37.PMID: 10961297 [PubMed - indexed for MEDLINE]Related articles