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    Results: 1 to 20 of 187

    2.

    Selection of insulinoma cell lines with resistance to interleukin-1beta- and gamma-interferon-induced cytotoxicity.

    Chen G, Hohmeier HE, Gasa R, Tran VV, Newgard CB.

    Diabetes. 2000 Apr;49(4):562-70.PMID: 10871193 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Expression of the transcription factor STAT-1 alpha in insulinoma cells protects against cytotoxic effects of multiple cytokines.

    Chen G, Hohmeier HE, Newgard CB.

    J Biol Chem. 2001 Jan 5;276(1):766-72.PMID: 11024034 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction.

    Rabinovitch A, Suarez-Pinzon W, Strynadka K, Ju Q, Edelstein D, Brownlee M, Korbutt GS, Rajotte RV.

    Diabetes. 1999 Jun;48(6):1223-9.PMID: 10342808 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Improvement of the mitochondrial antioxidant defense status prevents cytokine-induced nuclear factor-kappaB activation in insulin-producing cells.

    Azevedo-Martins AK, Lortz S, Lenzen S, Curi R, Eizirik DL, Tiedge M.

    Diabetes. 2003 Jan;52(1):93-101.PMID: 12502498 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Inflammatory mechanisms in diabetes: lessons from the beta-cell.

    Hohmeier HE, Tran VV, Chen G, Gasa R, Newgard CB.

    Int J Obes Relat Metab Disord. 2003 Dec;27 Suppl 3:S12-6. Review.PMID: 14704737 [PubMed - indexed for MEDLINE]Related articles

    8.

    Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicity.

    Karlsen AE, Rønn SG, Lindberg K, Johannesen J, Galsgaard ED, Pociot F, Nielsen JH, Mandrup-Poulsen T, Nerup J, Billestrup N.

    Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12191-6. Epub 2001 Oct 2.PMID: 11593036 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays.

    Cardozo AK, Kruhøffer M, Leeman R, Orntoft T, Eizirik DL.

    Diabetes. 2001 May;50(5):909-20.PMID: 11334433 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production.

    Hohmeier HE, Thigpen A, Tran VV, Davis R, Newgard CB.

    J Clin Invest. 1998 May 1;101(9):1811-20.PMID: 9576743 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells.

    Han X, Sun Y, Scott S, Bleich D.

    Diabetes. 2001 May;50(5):1047-55.PMID: 11334407 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress.

    Kharroubi I, Ladrière L, Cardozo AK, Dogusan Z, Cnop M, Eizirik DL.

    Endocrinology. 2004 Nov;145(11):5087-96. Epub 2004 Aug 5.PMID: 15297438 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production.

    Thomas HE, Darwiche R, Corbett JA, Kay TW.

    Diabetes. 2002 Feb;51(2):311-6.PMID: 11812737 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.
    15.

    MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity.

    Chen H, Li X, Epstein PN.

    Diabetes. 2005 May;54(5):1437-46.PMID: 15855331 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Adenoviral-induced islet cell cytotoxicity is not counteracted by Bcl-2 overexpression.

    Barbu AR, Akusjärvi G, Welsh N.

    Mol Med. 2002 Nov;8(11):733-41.PMID: 12520090 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    The role of oxygen-derived free radicals and nitric oxide in cytokine-induced antiproliferation of pancreatic cancer cells.

    Thomas WJ, Thomas DL, Knezetic JA, Adrian TE.

    Pancreas. 2002 Mar;24(2):161-8.PMID: 11854621 [PubMed - indexed for MEDLINE]Related articles

    18.

    Expression of a dominant negative inhibitor of NF-kappaB protects MIN6 beta-cells from cytokine-induced apoptosis.

    Baker MS, Chen X, Cao XC, Kaufman DB.

    J Surg Res. 2001 May 15;97(2):117-22.PMID: 11341786 [PubMed - indexed for MEDLINE]Related articles

    19.

    High glucose potentiates cytokine- and streptozotocin-induced apoptosis of rat islet cells: effect on apoptosis-related genes.

    Mellado-Gil JM, Aguilar-Diosdado M.

    J Endocrinol. 2004 Oct;183(1):155-62.PMID: 15525583 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Cytokine-induced apoptotic cell death in a mouse pancreatic beta-cell line: inhibition by Bcl-2.

    Iwahashi H, Hanafusa T, Eguchi Y, Nakajima H, Miyagawa J, Itoh N, Tomita K, Namba M, Kuwajima M, Noguchi T, Tsujimoto Y, Matsuzawa Y.

    Diabetologia. 1996 May;39(5):530-6.PMID: 8739912 [PubMed - indexed for MEDLINE]Related articles

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