PubMed

Insulin resistance and lipodystrophy in mice lacking ribosomal S6 kinase 2.

El-Haschimi K, Dufresne SD, Hirshman MF, Flier JS, Goodyear LJ, Bjørbaek C.

Diabetes. 2003 Jun;52(6):1340-6.PMID: 12765942 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout mice.

Dufresne SD, Bjørbaek C, El-Haschimi K, Zhao Y, Aschenbach WG, Moller DE, Goodyear LJ.

Mol Cell Biol. 2001 Jan;21(1):81-7.PMID: 11113183 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased serum leptin protects from adiposity despite the increased glucose uptake in white adipose tissue in mice lacking p85alpha phosphoinositide 3-kinase.

Terauchi Y, Matsui J, Kamon J, Yamauchi T, Kubota N, Komeda K, Aizawa S, Akanuma Y, Tomita M, Kadowaki T.

Diabetes. 2004 Sep;53(9):2261-70.PMID: 15331535 [PubMed - indexed for MEDLINE]Related articlesFree article

Induced adiposity and adipocyte hypertrophy in mice lacking the AMP-activated protein kinase-alpha2 subunit.

Villena JA, Viollet B, Andreelli F, Kahn A, Vaulont S, Sul HS.

Diabetes. 2004 Sep;53(9):2242-9.PMID: 15331533 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle.

Carvalho E, Kotani K, Peroni OD, Kahn BB.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E551-61. Epub 2005 May 31.PMID: 15928024 [PubMed - indexed for MEDLINE]Related articlesFree article

The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits.

Cawley NX, Zhou J, Hill JM, Abebe D, Romboz S, Yanik T, Rodriguiz RM, Wetsel WC, Loh YP.

Endocrinology. 2004 Dec;145(12):5807-19. Epub 2004 Sep 9.PMID: 15358678 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance.

Hazel M, Cooksey RC, Jones D, Parker G, Neidigh JL, Witherbee B, Gulve EA, McClain DA.

Endocrinology. 2004 May;145(5):2118-28. Epub 2003 Dec 18.PMID: 14684615 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocyte retinoid X receptor-alpha-deficient mice have reduced food intake, increased body weight, and improved glucose tolerance.

Wan YJ, Han G, Cai Y, Dai T, Konishi T, Leng AS.

Endocrinology. 2003 Feb;144(2):605-11.PMID: 12538623 [PubMed - indexed for MEDLINE]Related articlesFree article

p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling.

Sheffler DJ, Kroeze WK, Garcia BG, Deutch AY, Hufeisen SJ, Leahy P, Brüning JC, Roth BL.

Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4717-22. Epub 2006 Mar 10.PMID: 16537434 [PubMed - indexed for MEDLINE]Related articlesFree article

Markedly reduced white adipose tissue and increased insulin sensitivity in adcyap1-deficient mice.

Tomimoto S, Ojika T, Shintani N, Hashimoto H, Hamagami K, Ikeda K, Nakata M, Yada T, Sakurai Y, Shimada T, Morita Y, Ishida C, Baba A.

J Pharmacol Sci. 2008 May;107(1):41-8. Epub 2008 Apr 29.PMID: 18446003 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin and leptin resistance with hyperleptinemia in mice lacking androgen receptor.

Lin HY, Xu Q, Yeh S, Wang RS, Sparks JD, Chang C.

Diabetes. 2005 Jun;54(6):1717-25.PMID: 15919793 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of PYK2 in the development of obesity and insulin resistance.

Yu Y, Ross SA, Halseth AE, Hollenbach PW, Hill RJ, Gulve EA, Bond BR.

Biochem Biophys Res Commun. 2005 Sep 9;334(4):1085-91.PMID: 16039993 [PubMed - indexed for MEDLINE]Related articles

Effects of high-fat diet, angiotensinogen (agt) gene inactivation, and targeted expression to adipose tissue on lipid metabolism and renal gene expression.

Kim S, Urs S, Massiera F, Wortmann P, Joshi R, Heo YR, Andersen B, Kobayashi H, Teboul M, Ailhaud G, Quignard-Boulangé A, Fukamizu A, Jones BH, Kim JH, Moustaid-Moussa N.

Horm Metab Res. 2002 Nov-Dec;34(11-12):721-5.PMID: 12660889 [PubMed - indexed for MEDLINE]Related articles

Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.

Kubota N, Terauchi Y, Tobe K, Yano W, Suzuki R, Ueki K, Takamoto I, Satoh H, Maki T, Kubota T, Moroi M, Okada-Iwabu M, Ezaki O, Nagai R, Ueta Y, Kadowaki T, Noda T.

J Clin Invest. 2004 Oct;114(7):917-27.PMID: 15467830 [PubMed - indexed for MEDLINE]Related articlesFree article

K(ATP) channel knockout mice crossbred with transgenic mice expressing a dominant-negative form of human insulin receptor have glucose intolerance but not diabetes.

Kanezaki Y, Obata T, Matsushima R, Minami A, Yuasa T, Kishi K, Bando Y, Uehara H, Izumi K, Mitani T, Matsumoto M, Takeshita Y, Nakaya Y, Matsumoto T, Ebina Y.

Endocr J. 2004 Apr;51(2):133-44.PMID: 15118262 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice.

Yamauchi T, Oike Y, Kamon J, Waki H, Komeda K, Tsuchida A, Date Y, Li MX, Miki H, Akanuma Y, Nagai R, Kimura S, Saheki T, Nakazato M, Naitoh T, Yamamura K, Kadowaki T.

Nat Genet. 2002 Feb;30(2):221-6. Epub 2002 Jan 30.PMID: 11818964 [PubMed - indexed for MEDLINE]Related articles

Changes in glycemia by leptin administration or high- fat feeding in rodent models of obesity/type 2 diabetes suggest a link between resistin expression and control of glucose homeostasis.

Asensio C, Cettour-Rose P, Theander-Carrillo C, Rohner-Jeanrenaud F, Muzzin P.

Endocrinology. 2004 May;145(5):2206-13. Epub 2004 Feb 12.PMID: 14962997 [PubMed - indexed for MEDLINE]Related articlesFree article

The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.

Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk TH, Grefhorst A, Abdelkarim M, Caron S, Torpier G, Fruchart JC, Gonzalez FJ, Kuipers F, Staels B.

J Biol Chem. 2006 Apr 21;281(16):11039-49. Epub 2006 Jan 30.PMID: 16446356 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in adiponectin and inflammatory genes in response to hormonal imbalances in female mice and exacerbation of depot selective visceral adiposity by high-fat diet: implications for insulin resistance.

Zhang H, Chen X, Aravindakshan J, Sairam MR.

Endocrinology. 2007 Dec;148(12):5667-79. Epub 2007 Aug 23.PMID: 17717050 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity.

Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, Sticker M, Fumagalli S, Allegrini PR, Kozma SC, Auwerx J, Thomas G.

Nature. 2004 Sep 9;431(7005):200-5. Epub 2004 Aug 11. Erratum in: Nature. 2004 Sep 23;431(7007):485. PMID: 15306821 [PubMed - indexed for MEDLINE]Related articles