PubMed

Glucose 6-phosphate regulates hepatic glycogenolysis through inactivation of phosphorylase.

Aiston S, Andersen B, Agius L.

Diabetes. 2003 Jun;52(6):1333-9.PMID: 12765941 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular mode of inhibition of glycogenolysis in rat liver by the dihydropyridine derivative, BAY R3401: inhibition and inactivation of glycogen phosphorylase by an activated metabolite.

Bergans N, Stalmans W, Goldmann S, Vanstapel F.

Diabetes. 2000 Sep;49(9):1419-26.PMID: 10969824 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased potency and efficacy of combined phosphorylase inactivation and glucokinase activation in control of hepatocyte glycogen metabolism.

Hampson LJ, Agius L.

Diabetes. 2005 Mar;54(3):617-23.PMID: 15734835 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose 6-phosphate causes translocation of phosphorylase in hepatocytes and inactivates the enzyme synergistically with glucose.

Aiston S, Green A, Mukhtar M, Agius L.

Biochem J. 2004 Jan 1;377(Pt 1):195-204.PMID: 13678417 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucokinase and molecular aspects of liver glycogen metabolism.

Agius L.

Biochem J. 2008 Aug 15;414(1):1-18. Review.PMID: 18651836 [PubMed - indexed for MEDLINE]Related articles

Involvement of glucokinase translocation in the mechanism by which resorcinol inhibits glycolysis in hepatocytes.

Agius L.

Biochem J. 1997 Aug 1;325 ( Pt 3):667-73.PMID: 9271087 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid and amino acid modulation of glucose cycling in isolated rat hepatocytes.

Gustafson LA, Neeft M, Reijngoud DJ, Kuipers F, Sauerwein HP, Romijn JA, Herling AW, Burger HJ, Meijer AJ.

Biochem J. 2001 Sep 15;358(Pt 3):665-71.PMID: 11535127 [PubMed - indexed for MEDLINE]Related articlesFree article

The glycogenic action of protein targeting to glycogen in hepatocytes involves multiple mechanisms including phosphorylase inactivation and glycogen synthase translocation.

Green AR, Aiston S, Greenberg CC, Freeman S, Poucher SM, Brady MJ, Agius L.

J Biol Chem. 2004 Nov 5;279(45):46474-82. Epub 2004 Aug 18.PMID: 15322104 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-induced glycogenesis in the liver involves the glucose-6-phosphate-dependent dephosphorylation of glycogen synthase.

Cadefau J, Bollen M, Stalmans W.

Biochem J. 1997 Mar 15;322 ( Pt 3):745-50.PMID: 9148744 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose 6-phosphate produced by gluconeogenesis and by glucokinase is equally effective in activating hepatic glycogen synthase.

Gomis RR, Favre C, García-Rocha M, Fernández-Novell JM, Ferrer JC, Guinovart JJ.

J Biol Chem. 2003 Mar 14;278(11):9740-6. Epub 2003 Jan 7.PMID: 12519761 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of growth hormone deficiency on hormonal control of hepatic glycogenolysis in hypophysectomized rat.

Vidal H, Géloën A, Minaire Y, Riou JP.

Metabolism. 1993 May;42(5):631-7.PMID: 8492719 [PubMed - indexed for MEDLINE]Related articles

The physiological role of glucokinase binding and translocation in hepatocytes.

Agius L.

Adv Enzyme Regul. 1998;38:303-31.PMID: 9762360 [PubMed - indexed for MEDLINE]Related articles

Hepatic glycogen synthesis is highly sensitive to phosphorylase activity: evidence from metabolic control analysis.

Aiston S, Hampson L, Gómez-Foix AM, Guinovart JJ, Agius L.

J Biol Chem. 2001 Jun 29;276(26):23858-66. Epub 2001 Apr 17.PMID: 11309391 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation. Evidence against feedback inhibition of glucokinase.

Aiston S, Trinh KY, Lange AJ, Newgard CB, Agius L.

J Biol Chem. 1999 Aug 27;274(35):24559-66.PMID: 10455119 [PubMed - indexed for MEDLINE]Related articlesFree article

Inactivation of phosphorylase is a major component of the mechanism by which insulin stimulates hepatic glycogen synthesis.

Aiston S, Coghlan MP, Agius L.

Eur J Biochem. 2003 Jul;270(13):2773-81.PMID: 12823547 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycogen concentration and regulation of synthase activity in rat liver in vivo.

Niewoehner CB, Nuttall FQ.

Arch Biochem Biophys. 1995 Apr 20;318(2):271-8.PMID: 7733654 [PubMed - indexed for MEDLINE]Related articles

Allosteric regulation of liver phosphorylase a: revisited under approximated physiological conditions.

Ercan N, Gannon MC, Nuttall FQ.

Arch Biochem Biophys. 1996 Apr 15;328(2):255-64.PMID: 8645002 [PubMed - indexed for MEDLINE]Related articles

Diverse effects of two allosteric inhibitors on the phosphorylation state of glycogen phosphorylase in hepatocytes.

Latsis T, Andersen B, Agius L.

Biochem J. 2002 Nov 15;368(Pt 1):309-16.PMID: 12186629 [PubMed - indexed for MEDLINE]Related articlesFree article

On the inhibition of hepatic glycogenolysis by fructose. A 31P-NMR study in perfused rat liver using the fructose analogue 2,5-anhydro-D-mannitol.

Bruynseels K, Bergans N, Gillis N, van Dorpen F, Van Hecke P, Stalmans W, Vanstapel F.

NMR Biomed. 1999 May;12(3):145-56.PMID: 10414949 [PubMed - indexed for MEDLINE]Related articles

The control of hepatic glycogen metabolism in an in vitro model of sepsis.

Wallington J, Ning J, Titheradge MA.

Mol Cell Biochem. 2008 Jan;308(1-2):183-92. Epub 2007 Oct 13.PMID: 17934698 [PubMed - indexed for MEDLINE]Related articles