PubMed

Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics.

Kurzrock R, Kantarjian HM, Druker BJ, Talpaz M.

Ann Intern Med. 2003 May 20;138(10):819-30. Review.PMID: 12755554 [PubMed - indexed for MEDLINE]Related articlesFree article

[Bcr-Abl inhibition as molecular therapy approach in chronic myeloid leukemia]

Buchdunger E.

Med Klin (Munich). 2002 Jan 15;97 Suppl 1:2-6. German. PMID: 11831067 [PubMed - indexed for MEDLINE]Related articles

Dasatinib: a tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia and philadelphia chromosome-positive acute lymphoblastic leukemia.

Steinberg M.

Clin Ther. 2007 Nov;29(11):2289-308. Review.PMID: 18158072 [PubMed - indexed for MEDLINE]Related articles

Tyrosine kinase inhibitor as a therapeutic drug for chronic myelogenous leukemia and gastrointestinal stromal tumor.

Nakajima M, Toga W.

Nippon Yakurigaku Zasshi. 2003 Dec;122(6):482-90. Review.PMID: 14639002 [PubMed - indexed for MEDLINE]Related articles

In vitro effects of STI 571-containing drug combinations on the growth of Philadelphia-positive chronic myelogenous leukemia cells.

Scappini B, Onida F, Kantarjian HM, Dong L, Verstovsek S, Keating MJ, Beran M.

Cancer. 2002 May 15;94(10):2653-62.PMID: 12173333 [PubMed - indexed for MEDLINE]Related articles

The Bcr-Abl tyrosine kinase inhibitor imatinib and promising new agents against Philadelphia chromosome-positive leukemias.

Maekawa T, Ashihara E, Kimura S.

Int J Clin Oncol. 2007 Oct;12(5):327-40. Epub 2007 Oct 22. Review.PMID: 17929114 [PubMed - indexed for MEDLINE]Related articles

Imatinib mesylate: clinical results in Philadelphia chromosome-positive leukemias.

Kantarjian HM, Talpaz M.

Semin Oncol. 2001 Oct;28(5 Suppl 17):9-18. Review.PMID: 11740802 [PubMed - indexed for MEDLINE]Related articles

Molecular studies in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors.

Sawyers CL.

Semin Hematol. 2001 Jul;38(3 Suppl 8):15-21. Review.PMID: 11526597 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of resistance to imatinib mesylate in Bcr-Abl-positive leukemias.

Nimmanapalli R, Bhalla K.

Curr Opin Oncol. 2002 Nov;14(6):616-20. Review.PMID: 12409651 [PubMed - indexed for MEDLINE]Related articles

[Molecular targeted treatment--new treatment strategy for patients with chronic myeloid leukemia]

Usui N.

Rinsho Byori. 2004 Feb;52(2):136-44. Review. Japanese. PMID: 15027317 [PubMed - indexed for MEDLINE]Related articles

New tyrosine kinase inhibitors in chronic myeloid leukemia.

Martinelli G, Soverini S, Rosti G, Cilloni D, Baccarani M.

Haematologica. 2005 Apr;90(4):534-41.PMID: 15820950 [PubMed - indexed for MEDLINE]Related articlesFree article

The biology of signal transduction inhibition: basic science to novel therapies.

Griffin J.

Semin Oncol. 2001 Oct;28(5 Suppl 17):3-8. Review.PMID: 11740801 [PubMed - indexed for MEDLINE]Related articles

Important therapeutic targets in chronic myelogenous leukemia.

Kantarjian HM, Giles F, Quintás-Cardama A, Cortes J.

Clin Cancer Res. 2007 Feb 15;13(4):1089-97. Review.PMID: 17317816 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection of BCR-ABL gene mutations in Philadelphia chromosome positive leukemia patients resistant to STI-571 cancer therapy.

Chien JH, Tang JL, Chen RL, Li CC, Lee CP.

Leuk Res. 2008 Nov;32(11):1724-34. Epub 2008 Jul 7.PMID: 18603297 [PubMed - indexed for MEDLINE]Related articles

Beyond chronic myelogenous leukemia: potential role for imatinib in Philadelphia-negative myeloproliferative disorders.

Cortes J, Kantarjian H.

Cancer. 2004 May 15;100(10):2064-78. Review.PMID: 15139047 [PubMed - indexed for MEDLINE]Related articlesFree article

Current treatment approaches for chronic myelogenous leukemia.

Druker BJ.

Cancer J. 2001 Jul-Aug;7 Suppl 1:S14-8. Review.PMID: 11504279 [PubMed - indexed for MEDLINE]Related articles

Imatinib mesylate (Gleevec/Glivec) a molecular-targeted therapy for chronic myeloid leukaemia and other malignancies.

Nadal E, Olavarria E.

Int J Clin Pract. 2004 May;58(5):511-6. Review.PMID: 15206509 [PubMed - indexed for MEDLINE]Related articles

STI571: an inhibitor of the BCR-ABL tyrosine kinase for the treatment of chronic myelogenous leukaemia.

O'Dwyer ME, Druker BJ.

Lancet Oncol. 2000 Dec;1:207-11. Review.PMID: 11905636 [PubMed - indexed for MEDLINE]Related articles

Multifaceted approach to the treatment of bcr-abl-positive leukemias.

O'Dwyer M.

Oncologist. 2002;7 Suppl 1:30-8. Review.PMID: 11961207 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel targeted therapies to overcome imatinib mesylate resistance in chronic myeloid leukemia (CML).

Walz C, Sattler M.

Crit Rev Oncol Hematol. 2006 Feb;57(2):145-64. Epub 2005 Oct 5. Review.PMID: 16213151 [PubMed - indexed for MEDLINE]Related articles