PubMed

Adenovirus early region 3 antiapoptotic 10.4K, 14.5K, and 14.7K genes decrease the incidence of autoimmune diabetes in NOD mice.

Pierce MA, Chapman HD, Post CM, Svetlanov A, Efrat S, Horwitz M, Serreze DV.

Diabetes. 2003 May;52(5):1119-27.PMID: 12716741 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenovirus early region 3(E3) immunomodulatory genes decrease the incidence of autoimmune diabetes in NOD mice.

Efrat S, Serreze D, Svetlanov A, Post CM, Johnson EA, Herold K, Horwitz M.

Diabetes. 2001 May;50(5):980-4.PMID: 11334441 [PubMed - indexed for MEDLINE]Related articlesFree article

The adenovirus E3-14.7K protein and the E3-10.4K/14.5K complex of proteins, which independently inhibit tumor necrosis factor (TNF)-induced apoptosis, also independently inhibit TNF-induced release of arachidonic acid.

Krajcsi P, Dimitrov T, Hermiston TW, Tollefson AE, Ranheim TS, Vande Pol SB, Stephenson AH, Wold WS.

J Virol. 1996 Aug;70(8):4904-13.PMID: 8763993 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of human adenovirus early region 3 proteins (gp19K, 10.4K, 14.5K, and 14.7K) in a murine pneumonia model.

Sparer TE, Tripp RA, Dillehay DL, Hermiston TW, Wold WS, Gooding LR.

J Virol. 1996 Apr;70(4):2431-9.PMID: 8642671 [PubMed - indexed for MEDLINE]Related articlesFree article

The 10,400- and 14,500-dalton proteins encoded by region E3 of adenovirus function together to protect many but not all mouse cell lines against lysis by tumor necrosis factor.

Gooding LR, Ranheim TS, Tollefson AE, Aquino L, Duerksen-Hughes P, Horton TM, Wold WS.

J Virol. 1991 Aug;65(8):4114-23.PMID: 1830111 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of adenoviral E3 transgenes in beta cells prevents autoimmune diabetes.

von Herrath MG, Efrat S, Oldstone MB, Horwitz MS.

Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9808-13.PMID: 9275207 [PubMed - indexed for MEDLINE]Related articlesFree article

A 20-Mb region of chromosome 4 controls TNF-alpha-mediated CD8+ T cell aggression toward beta cells in type 1 diabetes.

Chamberlain G, Wållberg M, Rainbow D, Hunter K, Wicker LS, Green EA.

J Immunol. 2006 Oct 15;177(8):5105-14.PMID: 17015694 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.

Chong MM, Chen Y, Darwiche R, Dudek NL, Irawaty W, Santamaria P, Allison J, Kay TW, Thomas HE.

J Immunol. 2004 May 1;172(9):5714-21.PMID: 15100317 [PubMed - indexed for MEDLINE]Related articlesFree article

Construction and characterization of E1-minus replication-defective adenovirus vectors that express E3 proteins from the E1 region.

Toth K, Kuppuswamy M, Doronin K, Doronina O, Lichtenstein D, Tollefson A, Wold W.

Virology. 2002 Sep 15;301(1):99-108.PMID: 12359450 [PubMed - indexed for MEDLINE]Related articles

The adenovirus E3/10.4K-14.5K proteins down-modulate the apoptosis receptor Fas/Apo-1 by inducing its internalization.

Elsing A, Burgert HG.

Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10072-7.PMID: 9707602 [PubMed - indexed for MEDLINE]Related articlesFree article

MHC class I-mediated antigen presentation and induction of CD8+ cytotoxic T-cell responses in autoimmune diabetes-prone NOD mice.

Serreze DV, Gallichan WS, Snider DP, Croitoru K, Rosenthal KL, Leiter EH, Christianson GJ, Dudley ME, Roopenian DC.

Diabetes. 1996 Jul;45(7):902-8.PMID: 8666141 [PubMed - indexed for MEDLINE]Related articles

Adenovirus E3-10.4K/14.5K protein complex inhibits tumor necrosis factor-induced translocation of cytosolic phospholipase A2 to membranes.

Dimitrov T, Krajcsi P, Hermiston TW, Tollefson AE, Hannink M, Wold WS.

J Virol. 1997 Apr;71(4):2830-7.PMID: 9060638 [PubMed - indexed for MEDLINE]Related articlesFree article

Accelerated diabetes in rat insulin promoter-tumor necrosis factor-alpha transgenic nonobese diabetic mice lacking major histocompatibility class II molecules.

Rajagopalan G, Kudva YC, Flavell RA, David CS.

Diabetes. 2003 Feb;52(2):342-7.PMID: 12540606 [PubMed - indexed for MEDLINE]Related articlesFree article

Mouse anti-adenovirus cytotoxic T lymphocytes. Inhibition of lysis by E3 gp19K but not E3 14.7K.

Rawle FC, Tollefson AE, Wold WS, Gooding LR.

J Immunol. 1989 Sep 15;143(6):2031-7.PMID: 2789254 [PubMed - indexed for MEDLINE]Related articles

Diabetes resistance/susceptibility in T cells of nonobese diabetic mice conferred by MHC and MHC-linked genes.

Ueno A, Cho S, Cheng L, Wang Z, Wang B, Yang Y.

J Immunol. 2005 Oct 15;175(8):5240-7.PMID: 16210629 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice.

Marron MP, Graser RT, Chapman HD, Serreze DV.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13753-8. Epub 2002 Oct 2.PMID: 12361980 [PubMed - indexed for MEDLINE]Related articlesFree article

Deletion of the E3-6.7K/gp19K region reduces the persistence of wild-type adenovirus in a permissive tumor model in Syrian hamsters.

Bortolanza S, Bunuales M, Alzuguren P, Lamas O, Aldabe R, Prieto J, Hernandez-Alcoceba R.

Cancer Gene Ther. 2009 Sep;16(9):703-12. Epub 2009 Feb 20.PMID: 19229289 [PubMed - indexed for MEDLINE]Related articles

Adenovirus E3 14.7K protein functions in the absence of other adenovirus proteins to protect transfected cells from tumor necrosis factor cytolysis.

Horton TM, Ranheim TS, Aquino L, Kusher DI, Saha SK, Ware CF, Wold WS, Gooding LR.

J Virol. 1991 May;65(5):2629-39.PMID: 1850036 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenovirus early region 3 transgenes expressed in beta cells prevent autoimmune diabetes in nonobese diabetic mice: effects of deleting the adenovirus death protein 11.6K.

Pierce MA, Svetlanov A, Horwitz MS, Serreze DV.

J Virol. 2005 Jan;79(1):619-21.PMID: 15596856 [PubMed - indexed for MEDLINE]Related articlesFree article

Constitutive expression of the adenovirus E3-14.7K protein does not prolong adenovirus vector DNA persistence but protects mice against lipopolysaccharide-induced acute hepatitis.

Gantzer M, Spitz E, Accard N, Rooke R.

Hum Gene Ther. 2002 May 20;13(8):921-33.PMID: 12031125 [PubMed - indexed for MEDLINE]Related articles