PubMed

Adipose tissue is a major source of interleukin-1 receptor antagonist: upregulation in obesity and inflammation.

Juge-Aubry CE, Somm E, Giusti V, Pernin A, Chicheportiche R, Verdumo C, Rohner-Jeanrenaud F, Burger D, Dayer JM, Meier CA.

Diabetes. 2003 May;52(5):1104-10.PMID: 12716739 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-1 receptor antagonist is upregulated during diet-induced obesity and regulates insulin sensitivity in rodents.

Somm E, Cettour-Rose P, Asensio C, Charollais A, Klein M, Theander-Carrillo C, Juge-Aubry CE, Dayer JM, Nicklin MJ, Meda P, Rohner-Jeanrenaud F, Meier CA.

Diabetologia. 2006 Feb;49(2):387-93. Epub 2005 Dec 30.PMID: 16385385 [PubMed - indexed for MEDLINE]Related articles

Regulatory effects of interleukin (IL)-1, interferon-beta, and IL-4 on the production of IL-1 receptor antagonist by human adipose tissue.

Juge-Aubry CE, Somm E, Chicheportiche R, Burger D, Pernin A, Cuénod-Pittet B, Quinodoz P, Giusti V, Dayer JM, Meier CA.

J Clin Endocrinol Metab. 2004 Jun;89(6):2652-8.PMID: 15181037 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose tissue is a regulated source of interleukin-10.

Juge-Aubry CE, Somm E, Pernin A, Alizadeh N, Giusti V, Dayer JM, Meier CA.

Cytokine. 2005 Mar 21;29(6):270-4.PMID: 15749027 [PubMed - indexed for MEDLINE]Related articles

Adipose tissue has anti-inflammatory properties: focus on IL-1 receptor antagonist (IL-1Ra).

Dayer JM, Chicheportiche R, Juge-Aubry C, Meier C.

Ann N Y Acad Sci. 2006 Jun;1069:444-53.PMID: 16855172 [PubMed - indexed for MEDLINE]Related articles

Recent advances in the relationship between obesity, inflammation, and insulin resistance.

Bastard JP, Maachi M, Lagathu C, Kim MJ, Caron M, Vidal H, Capeau J, Feve B.

Eur Cytokine Netw. 2006 Mar;17(1):4-12. Review.PMID: 16613757 [PubMed - indexed for MEDLINE]Related articles

Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFalpha.

Chiellini C, Bertacca A, Novelli SE, Görgün CZ, Ciccarone A, Giordano A, Xu H, Soukas A, Costa M, Gandini D, Dimitri R, Bottone P, Cecchetti P, Pardini E, Perego L, Navalesi R, Folli F, Benzi L, Cinti S, Friedman JM, Hotamisligil GS, Maffei M.

J Cell Physiol. 2002 Feb;190(2):251-8.PMID: 11807829 [PubMed - indexed for MEDLINE]Related articles

Accelerated recovery from acute hypoxia in obese mice is due to obesity-associated up-regulation of interleukin-1 receptor antagonist.

Sherry CL, Kim SS, Freund GG.

Endocrinology. 2009 Jun;150(6):2660-7. Epub 2009 Feb 12.PMID: 19213834 [PubMed - indexed for MEDLINE]Related articles

Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells.

Fain JN.

Vitam Horm. 2006;74:443-77. Review.PMID: 17027526 [PubMed - indexed for MEDLINE]Related articles

Decreased fat mass in interleukin-1 receptor antagonist-deficient mice: impact on adipogenesis, food intake, and energy expenditure.

Somm E, Henrichot E, Pernin A, Juge-Aubry CE, Muzzin P, Dayer JM, Nicklin MJ, Meier CA.

Diabetes. 2005 Dec;54(12):3503-9.PMID: 16306368 [PubMed - indexed for MEDLINE]Related articlesFree article

Most of the interleukin 1 receptor antagonist, cathepsin S, macrophage migration inhibitory factor, nerve growth factor, and interleukin 18 release by explants of human adipose tissue is by the non-fat cells, not by the adipocytes.

Fain JN, Tichansky DS, Madan AK.

Metabolism. 2006 Aug;55(8):1113-21.PMID: 16839849 [PubMed - indexed for MEDLINE]Related articles

IL-1 receptor antagonist serum levels are increased in human obesity: a possible link to the resistance to leptin?

Meier CA, Bobbioni E, Gabay C, Assimacopoulos-Jeannet F, Golay A, Dayer JM.

J Clin Endocrinol Metab. 2002 Mar;87(3):1184-8.PMID: 11889184 [PubMed - indexed for MEDLINE]Related articlesFree article

Mouse IL-1 receptor antagonist isoforms: complementary DNA cloning and protein expression of intracellular isoform and tissue distribution of secreted and intracellular IL-1 receptor antagonist in vivo.

Gabay C, Porter B, Fantuzzi G, Arend WP.

J Immunol. 1997 Dec 15;159(12):5905-13.PMID: 9550387 [PubMed - indexed for MEDLINE]Related articles

Interleukin-1 receptor antagonist gene polymorphism and traditional classification in obese women.

Um JY, Kim HM, Mun SW, Song YS, Hong SH.

Int J Neurosci. 2006 Jan;116(1):39-53.PMID: 16318998 [PubMed - indexed for MEDLINE]Related articles

Protective effects of IL-1Ra or vIL-10 gene transfer on a murine model of wear debris-induced osteolysis.

Yang SY, Wu B, Mayton L, Mukherjee P, Robbins PD, Evans CH, Wooley PH.

Gene Ther. 2004 Mar;11(5):483-91.PMID: 14724688 [PubMed - indexed for MEDLINE]Related articles

Beta-(1-->3)-D-glucan modulates DNA binding of nuclear factors kappaB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1beta/IL-1 receptor antagonist ratio.

Luhm J, Langenkamp U, Hensel J, Frohn C, Brand JM, Hennig H, Rink L, Koritke P, Wittkopf N, Williams DL, Mueller A.

BMC Immunol. 2006 Mar 22;7:5.PMID: 16553947 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of interleukin-15 (IL-15) on adipose tissue mass in rodent obesity models: evidence for direct IL-15 action on adipose tissue.

Alvarez B, Carbó N, López-Soriano J, Drivdahl RH, Busquets S, López-Soriano FJ, Argilés JM, Quinn LS.

Biochim Biophys Acta. 2002 Feb 15;1570(1):33-7.PMID: 11960686 [PubMed - indexed for MEDLINE]Related articles

Production of IL-1 receptor antagonist by hepatocytes is regulated as an acute-phase protein in vivo.

Gabay C, Gigley J, Sipe J, Arend WP, Fantuzzi G.

Eur J Immunol. 2001 Feb;31(2):490-9.PMID: 11180114 [PubMed - indexed for MEDLINE]Related articles

Effects of chronic exercise on cytokine production in white adipose tissue and skeletal muscle of rats.

Gomez-Merino D, Drogou C, Guezennec CY, Chennaoui M.

Cytokine. 2007 Oct;40(1):23-9. Epub 2007 Sep 7.PMID: 17826174 [PubMed - indexed for MEDLINE]Related articles

Interleukin 1 receptor antagonist gene expression in rat pituitary in the systemic inflammatory response syndrome: pathophysiological implications.

Licinio J, Wong ML.

Mol Psychiatry. 1997 Mar;2(2):99-103.PMID: 9106226 [PubMed - indexed for MEDLINE]Related articles