PubMed

Insulin does not mediate glucose stimulation of proinsulin biosynthesis.

Leibowitz G, Oprescu AI, Uçkaya G, Gross DJ, Cerasi E, Kaiser N.

Diabetes. 2003 Apr;52(4):998-1003.PMID: 12663472 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-regulated proinsulin gene expression is required for adequate insulin production during chronic glucose exposure.

Leibowitz G, Uçkaya G, Oprescu AI, Cerasi E, Gross DJ, Kaiser N.

Endocrinology. 2002 Sep;143(9):3214-20.PMID: 12193532 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin.

Wicksteed B, Alarcon C, Briaud I, Lingohr MK, Rhodes CJ.

J Biol Chem. 2003 Oct 24;278(43):42080-90. Epub 2003 Aug 18.PMID: 12928442 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line.

Skelly RH, Schuppin GT, Ishihara H, Oka Y, Rhodes CJ.

Diabetes. 1996 Jan;45(1):37-43.PMID: 8522057 [PubMed - indexed for MEDLINE]Related articles

Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level.

Alarcon C, Wicksteed B, Rhodes CJ.

Diabetologia. 2006 Dec;49(12):2920-9. Epub 2006 Oct 20.PMID: 17053883 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial regulation of insulin production in rat pancreatic islets.

Leibowitz G, Khaldi MZ, Shauer A, Parnes M, Oprescu AI, Cerasi E, Jonas JC, Kaiser N.

Diabetologia. 2005 Aug;48(8):1549-59. Epub 2005 Jun 29.PMID: 15986240 [PubMed - indexed for MEDLINE]Related articles

Syntaxin, but not soluble NSF attachment protein (SNAP), biosynthesis by rat pancreatic islets is regulated by glucose in parallel with proinsulin biosynthesis.

Nagamatsu S, Nakamichi Y, Katahira H.

Diabetologia. 1997 Dec;40(12):1396-402.PMID: 9447946 [PubMed - indexed for MEDLINE]Related articles

Glucose regulated insulin biosynthesis in isolated rat pancreatic islets is accompanied by changes in proinsulin mRNA.

Giddings SJ, Chirgwin JM, Permutt MA.

Diabetes Res. 1985 Mar;2(2):71-5.PMID: 3899462 [PubMed - indexed for MEDLINE]Related articles

Effects of galanin on proinsulin mRNA and insulin biosynthesis in normal islets.

Lindskog S, Gregersen S, Hermansen K, Ahrén B.

Regul Pept. 1995 Aug 22;58(3):135-9.PMID: 8577925 [PubMed - indexed for MEDLINE]Related articles

Acute inhibition of proinsulin biosynthesis at the translational level by palmitic acid.

Katahira H, Nagamatsu S, Ozawa S, Nakamichi Y, Yamaguchi S, Furukawa H, Takizawa M, Yoshimoto K, Itagaki E, Ishida H.

Biochem Biophys Res Commun. 2001 Mar 30;282(2):507-10.PMID: 11401488 [PubMed - indexed for MEDLINE]Related articles

Effects of aging on insulin synthesis and secretion. Differential effects on preproinsulin messenger RNA levels, proinsulin biosynthesis, and secretion of newly made and preformed insulin in the rat.

Wang SY, Halban PA, Rowe JW.

J Clin Invest. 1988 Jan;81(1):176-84.PMID: 3275693 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycerol-stimulated proinsulin biosynthesis in isolated pancreatic rat islets via adenoviral-induced expression of glycerol kinase is mediated via mitochondrial metabolism.

Skelly RH, Wicksteed B, Antinozzi PA, Rhodes CJ.

Diabetes. 2001 Aug;50(8):1791-8.PMID: 11473040 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of islet amyloid polypeptide (IAPP) on insulin biosynthesis or secretion in rat islets and mouse beta TC3 cells. Biosynthesis of IAPP in mouse beta TC3 cells.

Nagamatsu S, Nishi M, Steiner DF.

Diabetes Res Clin Pract. 1992 Jan;15(1):49-55.PMID: 1541235 [PubMed - indexed for MEDLINE]Related articles

Age-related impairment in the short term regulation of insulin biosynthesis by glucose in rat pancreatic islets.

Wang SY, Rowe JW.

Endocrinology. 1988 Aug;123(2):1008-13.PMID: 2456199 [PubMed - indexed for MEDLINE]Related articles

Lack of islet amyloid polypeptide regulation of insulin biosynthesis or secretion in normal rat islets.

Nagamatsu S, Carroll RJ, Grodsky GM, Steiner DF.

Diabetes. 1990 Jul;39(7):871-4.PMID: 2191889 [PubMed - indexed for MEDLINE]Related articles

Differential expression of rat pancreatic islet beta-cell glucose transporter (GLUT 2), proinsulin and islet amyloid polypeptide genes after prolonged fasting, insulin-induced hypoglycaemia and dexamethasone treatment.

Koranyi L, Bourey R, Turk J, Mueckler M, Permutt MA.

Diabetologia. 1992 Dec;35(12):1125-32.PMID: 1282477 [PubMed - indexed for MEDLINE]Related articles

Transcriptional and translational control of glucose-stimulated (pro)insulin biosynthesis.

Jahr H, Schröder D, Ziegler B, Ziegler M, Zühlke H.

Eur J Biochem. 1980 Sep;110(2):499-505.PMID: 6160039 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells.

Schuppin GT, Rhodes CJ.

Biochem J. 1996 Jan 1;313 ( Pt 1):259-68.PMID: 8546693 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of insulin secretion and proinsulin biosynthesis by succinate.

Attali V, Parnes M, Ariav Y, Cerasi E, Kaiser N, Leibowitz G.

Endocrinology. 2006 Nov;147(11):5110-8. Epub 2006 Aug 17.PMID: 16916949 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-stimulated insulin biosynthesis depends on insulin-stimulated insulin gene transcription.

Leibiger B, Wahlander K, Berggren PO, Leibiger IB.

J Biol Chem. 2000 Sep 29;275(39):30153-6.PMID: 10913151 [PubMed - indexed for MEDLINE]Related articlesFree article